• 42 Hits
  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins c-akt)
Species Resource Title
Human and Animal Cells HL60(RCB0041) , U937 , Jurkat Hypoxia-inducible factor 1α inhibitor induces cell death via suppression of BCR-ABL1 and Met expression in BCR-ABL1 tyrosine kinase inhibitor sensitive and resistant chronic myeloid leukemia cells.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) , HMMME(RCB0819) Immunostimulatory oncolytic activity of coxsackievirus A11 in human malignant pleural mesothelioma.
Human and Animal Cells GCIY(RCB0555) , GSU(RCB2278) , HGC-27(RCB0500) , KE-39(RCB1434) , MKN-7(RCB3687) , SH-10-TC(RCB1940) p70S6K/Akt dual inhibitor DIACC3010 is efficacious in preclinical models of gastric cancer alone and in combination with trastuzumab.
Human and Animal Cells SSP-25(RCB1293) Mucin 4 Confers Gemcitabine Resistance and an Unfavorable Prognosis in Patients with Cholangiocarcinoma via AKT Activation.
Human and Animal Cells OS-RC-2(RCB0735) ELOVL5-mediated fatty acid elongation promotes cellular proliferation and invasion in renal cell carcinoma.
Human and Animal Cells MDCK(RCB0995) Down-regulation of Mcl-1 by inhibition of the PI3-K/Akt pathway is required for cell shrinkage-dependent cell death.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Human and Animal Cells MH7A(RCB1512) A Novel Drug Combination of Mangiferin and Cinnamic Acid Alleviates Rheumatoid Arthritis by Inhibiting TLR4/NFκB/NLRP3 Activation-Induced Pyroptosis.
Drosophila DGRC#106635 , DGRC#107532 Heat shock cognate 70 genes contribute to Drosophila spermatocyte growth progression possibly through the insulin signaling pathway.
Human and Animal Cells MKN74(RCB1002) , Kato III(RCB2088) , SH-10-TC(RCB1940) FOXO3 is a latent tumor suppressor for FOXO3-positive and cytoplasmic-type gastric cancer cells.
Human and Animal Cells U-937 DE-4(RCB0435) Involvement of Ras/extracellular signal-regulated kinase, but not Akt pathway in risedronate-induced apoptosis of U937 cells and its suppression by cytochalasin B.
Human and Animal Cells KGN(RCB1154) Novel regulation of PKC-induced inflammation by Akt and protein phosphatase 2A in ovarian granulosa cells.
Human and Animal Cells ATDC5(RCB0565) Involvement of the phosphoinositide 3-kinase/protein kinase B signaling pathway in insulin/IGF-I-induced chondrogenesis of the mouse embryonal carcinoma-derived cell line ATDC5.
Human and Animal Cells Hepa 1-6(RCB1638) , YAC-1 Everolimus enhances TRAIL-mediated anti-tumor activity of liver resident natural killer cells in mice.
Human and Animal Cells MG6(RCB2403) Infection of microglia with Porphyromonas gingivalis promotes cell migration and an inflammatory response through the gingipain-mediated activation of protease-activated receptor-2 in mice.
Human and Animal Cells GM95(RCB1026) Integrin-mediated signaling induced by simian virus 40 leads to transient uncoupling of cortical actin and the plasma membrane.
Human and Animal Cells Inhibition of the antigen-induced activation of rodent mast cells by putative Janus kinase 3 inhibitors WHI-P131 and WHI-P154 in a Janus kinase 3-independent manner.
Human and Animal Cells ATDC5(RCB0565) Insulin-like growth factor-I signaling is modified during chondrocyte differentiation.
Human and Animal Cells Dexamethasone inhibits insulin-induced chondrogenesis of ATDC5 cells by preventing PI3K-Akt signaling and DNA binding of Runx2.
Human and Animal Cells Epidermal growth factor and interleukin-1beta synergistically stimulate the production of nitric oxide in rat intestinal epithelial cells.