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  • 21 Hits
  • Search Condition : Filter (MeSH = Proto-Oncogene Proteins c-met / genetics)
Species Resource Title
Human and Animal Cells Ba/F3(RCB0805) , WEHI-3(RCB0035) Foretinib can overcome common on-target resistance mutations after capmatinib/tepotinib treatment in NSCLCs with MET exon 14 skipping mutation.
Human and Animal Cells EBC-1(RCB1965) Met-HER3 crosstalk supports proliferation via MPZL3 in MET-amplified cancer cells.
Zebrafish giraffe rw716 Retinoic Acid Organizes the Zebrafish Vagus Motor Topographic Map via Spatiotemporal Coordination of Hgf/Met Signaling.
Human and Animal Cells MKN45(RCB1001) Combined drug action of 2-phenylimidazo[2,1-b]benzothiazole derivatives on cancer cells according to their oncogenic molecular signatures.
Human and Animal Cells PC-9(RCB4455) Activation of KRAS Mediates Resistance to Targeted Therapy in MET Exon 14-mutant Non-small Cell Lung Cancer.
Human and Animal Cells PC-3(RCB2145) Altered miRNA expression in high-fat diet-induced prostate cancer progression.
Human and Animal Cells HS-SY-II(RCB2231) Functional and therapeutic relevance of hepatocyte growth factor/c-MET signaling in synovial sarcoma.
Human and Animal Cells MKN45(RCB1001) In Vitro and In Vivo Activity of AMG 337, a Potent and Selective MET Kinase Inhibitor, in MET-Dependent Cancer Models.
Human and Animal Cells HuCCT1(RCB1960) , TFK-1(RCB2537) Targeting c-MET by Tivantinib through synergistic activation of JNK/c-jun pathway in cholangiocarcinoma.
Human and Animal Cells MRC-5 Ability of the Met kinase inhibitor crizotinib and new generation EGFR inhibitors to overcome resistance to EGFR inhibitors.
Human and Animal Cells KP4(RCB1005) Bispecific antibodies with natural architecture produced by co-culture of bacteria expressing two distinct half-antibodies.
Human and Animal Cells A preclinical algorithm of soluble surrogate biomarkers that correlate with therapeutic inhibition of the MET oncogene in gastric tumors.
Human and Animal Cells COLO 679(RCB0989) , 293(RCB1637) A ubiquitin ligase, skeletrophin, is a negative regulator of melanoma invasion.
Human and Animal Cells LoVo(RCB1639) Activation of hepatocyte growth factor/scatter factor in colorectal carcinoma.
Human and Animal Cells Hepatocyte growth factor suppresses the anticancer effect of irinotecan by decreasing the level of active metabolite in HepG2 cells.
Human and Animal Cells Co-activation of epidermal growth factor receptor and c-MET defines a distinct subset of lung adenocarcinomas.
Human and Animal Cells Molecular predictors of sensitivity to the MET inhibitor PHA665752 in lung carcinoma cells.
Human and Animal Cells ACC-MESO-1(RCB2292) , ACC-MESO-4(RCB2293) Inhibition of Met/HGF receptor and angiogenesis by NK4 leads to suppression of tumor growth and migration in malignant pleural mesothelioma.
Human and Animal Cells MKN45(RCB1001) Inhibition of Src impairs the growth of met-addicted gastric tumors.
Human and Animal Cells MKN45(RCB1001) HER kinase activation confers resistance to MET tyrosine kinase inhibition in MET oncogene-addicted gastric cancer cells.