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  • Search Condition : Filter (MeSH = Pyrrolidines / pharmacology*)
Species Resource Title
Human and Animal Cells HSC-2(RCB1945) , HSC-4(RCB1902) Efficacy of a Novel Oral Chemotherapeutic Agent, TAS-102, Against Human Oral Squamous Cell Carcinoma Cells.
Human and Animal Cells TE-1(RCB1894) , TE-10(RCB2099) , TE-11(RCB2100) Synthetic Lethality with Trifluridine/Tipiracil and Checkpoint Kinase 1 Inhibitor for Esophageal Squamous Cell Carcinoma.
Human and Animal Cells PC-9(RCB4455) Discovery of N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidine-3-yl)acrylamide (PF-06747775) through Structure-Based Drug Design: A High Affinity Irreversible Inhibitor Targeting Oncogenic EGFR Mutants with Selectivity over Wild-Type EGFR.
Human and Animal Cells Ba/F3(RCB0805) , II-18(RCB2093) , A431(RCB1872) Mutant-Selective Irreversible EGFR Inhibitor, Naquotinib, Inhibits Tumor Growth in NSCLC Models with EGFR-Activating Mutations, T790M Mutation, and AXL Overexpression.
Human and Animal Cells JHOS-2(RCB1521) , JHOS-3(RCB1546) , JHOS-4(RCB1678) Histone methyltransferase SMYD2 selective inhibitor LLY-507 in combination with poly ADP ribose polymerase inhibitor has therapeutic potential against high-grade serous ovarian carcinomas.
Mice , Human and Animal Cells RBRC00806 , Atg5^(-/-)MEF(RCB2711) , Atg5^(+/+)MEF(RCB2710) Novel Ridaifen-B Structure Analog Induces Apoptosis and Autophagy Depending on Pyrrolidine Side Chain.
Human and Animal Cells SK-N-SH(RCB0426) α-Pyrrolidinononanophenone provokes apoptosis of neuronal cells through alterations in antioxidant properties.
Human and Animal Cells U251(RCB0461) Molecular basis of anti-apoptotic effect of immunophilin ligands on hydrogen peroxide-induced apoptosis in human glioma cells.
Human and Animal Cells MEB4(RCB1027) , GM95(RCB1026) Influence of cellular ganglioside depletion on tumor formation.