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  • 検索条件 : 絞込み (MeSH = TOR Serine-Threonine Kinases)
生物種 リソース名 タイトル
遺伝子材料 p3xFLAG-CMV10-hTel2 (RDB19795) , p3xFLAG-CMV10-hTti1 (RDB19800) Tti1 and Tel2 are critical factors in mammalian target of rapamycin complex assembly.
遺伝子材料 pMXs-IP-EGFP-hATG13 (RDB19625) , pME18s-HA-hFIP200 (RDB19769) , pEGFP-C1-hAtg13 (RDB19770) , p3xFLAG-CMV10-hAtg13 (RDB19771) , p3xFLAG-CMV14-mULK1 (RDB19772) Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy.
遺伝子材料 pMXs-IP-EGFP-hFIP200 (RDB19623) , pMXs-IP-EGFP-mAtg5 (RDB19634) , p3xFLAG-CMV10-hFIP200 (RDB19762) , pMXs-IP-EGFP-ULK1(K46N) (RDB19780) , pMXs-IP-EGFP-LC3 (RDB19798) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
ヒト・動物細胞 A549(RCB0098) The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets.
ヒト・動物細胞 PC-3(RCB2145) Asteltoxin inhibits extracellular vesicle production through AMPK/mTOR-mediated activation of lysosome function.
ヒト・動物細胞 ST2(RCB0224) Peptide drugs accelerate BMP-2-induced calvarial bone regeneration and stimulate osteoblast differentiation through mTORC1 signaling.
ヒト・動物細胞 CACO-2(RCB0988) , COLO205(RCB2127) Rebamipide suppresses 5-fluorouracil-induced cell death via the activation of Akt/mTOR pathway and regulates the expression of Bcl-2 family proteins.
ヒト・動物細胞 PC-12(RCB0009) Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
ヒト・動物細胞 ATDC5(RCB0565) mTOR signaling contributes to chondrocyte differentiation.
ヒト・動物細胞 MC3T3-E1(RCB1126) Ultrasound induces hypoxia-inducible factor-1 activation and inducible nitric-oxide synthase expression through the integrin/integrin-linked kinase/Akt/mammalian target of rapamycin pathway in osteoblasts.
ヒト・動物細胞 Amino acid limitation induces expression of ATF5 mRNA at the post-transcriptional level.
ヒト・動物細胞 B16 melanoma Negative regulation of melanogenesis by phospholipase D1 through mTOR/p70 S6 kinase 1 signaling in mouse B16 melanoma cells.
ヒト・動物細胞 Cyclin D1 expression mediated by phosphatidylinositol 3-kinase through mTOR-p70(S6K)-independent signaling in growth factor-stimulated NIH 3T3 fibroblasts.
ヒト・動物細胞 Inhibition of MEK/ERK signaling induces apoptosis of acute myelogenous leukemia cells via inhibition of eukaryotic initiation factor 4E-binding protein 1 and down-regulation of Mcl-1.
ヒト・動物細胞 Leucine restriction inhibits chondrocyte proliferation and differentiation through mechanisms both dependent and independent of mTOR signaling.
ショウジョウバエ 6975R-2 , 6975R-8 AKT and TOR signaling set the pace of the circadian pacemaker.
ショウジョウバエ 16908R-1 Modularity and hormone sensitivity of the Drosophila melanogaster insulin receptor/target of rapamycin interaction proteome.
ショウジョウバエ Multifaceted roles of PTEN and TSC orchestrate growth and differentiation of Drosophila blood progenitors.
ヒト・動物細胞 ST2(RCB0224) Down-regulation of mTOR leads to up-regulation of osteoprotegerin in bone marrow cells.
ショウジョウバエ 5092R-2 , 4320R-2 , 10539R-3 MAP4K3 is a component of the TORC1 signalling complex that modulates cell growth and viability in Drosophila melanogaster.