1. Home
  2. List
Reference Patent

Reference - List

  • 17 Hits
  • Search Condition : Filter (MeSH = alpha-Synuclein / genetics)
Species Resource Title
Human and Animal Cells KG-1-C(RCB0270) Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation.
Mice RBRC02370 Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
C.elegans tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
Drosophila MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
Mice RBRC06342 Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
Yeast High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast.
Drosophila Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
Human and Animal Cells 201B7(HPS0063) , 409B2(HPS0076) Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
Drosophila Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
C.elegans tm1898 , tm2058 LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
C.elegans tm5447 Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.
Mice RBRC00806 AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
C.elegans tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
C.elegans tm1779 , tm918 , tm598 The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.
C.elegans tm4634 Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
Drosophila 1009R-2 , 1009R-3 Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
C.elegans tm598 , tm395 A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress.