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  • 検索条件 : 絞込み (MeSH = alpha-Synuclein / genetics)
生物種 リソース名 タイトル
一般微生物 JCM12987 , JCM8349 , JCM16131 , JCM8353 , JCM15918 Actinomyces viscosus promotes neuroprotection in C. elegans models of Parkinson's disease.
ショウジョウバエ DGRC#113956 Altered reactivity to threatening stimuli in Drosophila models of Parkinson's disease, revealed by a trial-based assay.
ゼブラフィッシュ UAS:BoTxBLCGFP, UAS:GCaMP7a Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration.
ヒト・動物細胞 KG-1-C(RCB0270) Epsin2, a novel target for multiple system atrophy therapy via α-synuclein/FABP7 propagation.
実験動物マウス RBRC02370 Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
線虫 tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
ショウジョウバエ MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
実験動物マウス RBRC06342 Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
酵母 High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast.
ショウジョウバエ Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
ヒト・動物細胞 201B7(HPS0063) , 409B2(HPS0076) Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
ショウジョウバエ Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
線虫 Loss of glutathione redox homeostasis impairs proteostasis by inhibiting autophagy-dependent protein degradation.
線虫 tm1898 , tm2058 LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
線虫 tm5447 Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.
実験動物マウス RBRC00806 AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
線虫 tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
線虫 tm1779 , tm918 , tm598 The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.
線虫 tm4634 Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
ショウジョウバエ 1009R-2 , 1009R-3 Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.