生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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実験動物マウス
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RBRC02370
|
78262
|
Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
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Nat Commun |
2024-2-16 |
Pubmed
Full text
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線虫
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tm4909
|
76035
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The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
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EMBO J |
2021-11-2 |
Pubmed
Full text
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ショウジョウバエ
|
|
74704
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MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
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Cell Rep |
2022-12-20 |
Pubmed
Full text
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実験動物マウス
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RBRC06342
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73527
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Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
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FASEB J |
2023-2-1 |
Pubmed
Full text
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酵母
|
|
73056
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High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast.
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Elife |
2022-4-19 |
Pubmed
Full text
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ショウジョウバエ
|
|
70793
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Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
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Gene |
2021-10-5 |
Pubmed
Full text
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ヒト・動物細胞
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201B7(HPS0063)
,
409B2(HPS0076)
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63219
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Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
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FEBS Open Bio |
2021-2-1 |
Pubmed
Full text
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ショウジョウバエ
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|
59152
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Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
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Proc Natl Acad Sci U S A |
2019-10-8 |
Pubmed
Full text
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線虫
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tm1898
,
tm2058
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55859
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LRRK2 kinase regulates α-synuclein propagation via RAB35 phosphorylation.
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Nat Commun |
2018-8-27 |
Pubmed
Full text
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線虫
|
tm5447
|
51462
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Novel animal model defines genetic contributions for neuron-to-neuron transfer of α-synuclein.
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Sci Rep |
2017-8-8 |
Pubmed
Full text
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実験動物マウス
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RBRC00806
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47304
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AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
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Brain Pathol |
2018-1-1 |
Pubmed
Full text
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線虫
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tm1961
,
tm474
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46038
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Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
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Invert Neurosci |
2011-12-1 |
Pubmed
Full text
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線虫
|
tm1779
,
tm918
,
tm598
|
45930
|
The effects of pdr1, djr1.1 and pink1 loss in manganese-induced toxicity and the role of α-synuclein in C. elegans.
|
Metallomics |
2014-3-1 |
Pubmed
Full text
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線虫
|
tm4634
|
31380
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Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
|
Hum Mol Genet |
2015-3-1 |
Pubmed
Full text
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ショウジョウバエ
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1009R-2
,
1009R-3
|
22705
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Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
|
Hum Mol Genet |
2010-12-1 |
Pubmed
Full text
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線虫
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tm598
,
tm395
|
3400
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A Caenorhabditis elegans Parkin mutant with altered solubility couples alpha-synuclein aggregation to proteotoxic stress.
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Hum Mol Genet |
2005-11-15 |
Pubmed
Full text
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