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  • 検索条件 : 絞込み (MeSH = alpha-Synuclein / metabolism)
生物種 リソース名 タイトル
実験動物マウス RBRC02370 Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
線虫 tm4909 The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
ヒト・動物細胞 293(RCB1637) Sortilin acts as an endocytic receptor for α-synuclein fibril.
ショウジョウバエ MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
実験動物マウス RBRC06342 Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
酵母 High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast.
ショウジョウバエ DGRC#118739 , DGRC#118740 Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson's disease.
ショウジョウバエ Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
ヒト・動物細胞 201B7(HPS0063) , 409B2(HPS0076) Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
実験動物マウス RBRC02830 Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease.
ショウジョウバエ Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
線虫 tm4909 Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
線虫 tm1779 , tm598 A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans.
実験動物マウス RBRC00806 AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
線虫 tm1961 , tm474 Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
線虫 tm4634 Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
ショウジョウバエ 1009R-2 , 1009R-3 Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
線虫 tm2912 A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.