生物種
|
リソース名
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RRC ID
|
タイトル
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ジャーナル
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公開日
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外部リンク
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実験動物マウス
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RBRC02370
|
78262
|
Reduced progranulin increases tau and α-synuclein inclusions and alters mouse tauopathy phenotypes via glucocerebrosidase.
|
Nat Commun |
2024-2-16 |
Pubmed
Full text
|
線虫
|
tm4909
|
76035
|
The cellular modifier MOAG-4/SERF drives amyloid formation through charge complementation.
|
EMBO J |
2021-11-2 |
Pubmed
Full text
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ヒト・動物細胞
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293(RCB1637)
|
75807
|
Sortilin acts as an endocytic receptor for α-synuclein fibril.
|
FASEB J |
2023-7-1 |
Pubmed
Full text
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ショウジョウバエ
|
|
74704
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MED13 and glycolysis are conserved modifiers of α-synuclein-associated neurodegeneration.
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Cell Rep |
2022-12-20 |
Pubmed
Full text
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実験動物マウス
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RBRC06342
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73527
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Distinct effects of SDC3 and FGFRL1 on selective neurodegeneration in AD and PD.
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FASEB J |
2023-2-1 |
Pubmed
Full text
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酵母
|
|
73056
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High and stable ATP levels prevent aberrant intracellular protein aggregation in yeast.
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Elife |
2022-4-19 |
Pubmed
Full text
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ショウジョウバエ
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DGRC#118739
,
DGRC#118740
|
71789
|
Light-driven activation of mitochondrial proton-motive force improves motor behaviors in a Drosophila model of Parkinson's disease.
|
Commun Biol |
2019-1-1 |
Pubmed
Full text
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ショウジョウバエ
|
|
70793
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Saffron ameliorated motor symptoms, short life span and retinal degeneration in Parkinson's disease fly models.
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Gene |
2021-10-5 |
Pubmed
Full text
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ヒト・動物細胞
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201B7(HPS0063)
,
409B2(HPS0076)
|
63219
|
Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication.
|
FEBS Open Bio |
2021-2-1 |
Pubmed
Full text
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実験動物マウス
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RBRC02830
|
60828
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Amido-bridged nucleic acid (AmNA)-modified antisense oligonucleotides targeting α-synuclein as a novel therapy for Parkinson's disease.
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Sci Rep |
2019-5-21 |
Pubmed
Full text
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ショウジョウバエ
|
|
59152
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Parkinson's disease-associated iPLA2-VIA/PLA2G6 regulates neuronal functions and α-synuclein stability through membrane remodeling.
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Proc Natl Acad Sci U S A |
2019-10-8 |
Pubmed
Full text
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線虫
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tm4909
|
54285
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Identification of MOAG-4/SERF as a regulator of age-related proteotoxicity.
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Cell |
2010-8-20 |
Pubmed
Full text
|
線虫
|
tm1779
,
tm598
|
53495
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A bacterial metabolite induces glutathione-tractable proteostatic damage, proteasomal disturbances, and PINK1-dependent autophagy in C. elegans.
|
Cell Death Dis |
2015-10-15 |
Pubmed
Full text
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実験動物マウス
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RBRC00806
|
47304
|
AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
|
Brain Pathol |
2018-1-1 |
Pubmed
Full text
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線虫
|
tm1961
,
tm474
|
46038
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Caenorhabditis elegans as an experimental tool for the study of complex neurological diseases: Parkinson's disease, Alzheimer's disease and autism spectrum disorder.
|
Invert Neurosci |
2011-12-1 |
Pubmed
Full text
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線虫
|
tm4634
|
31380
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Glutaredoxin deficiency exacerbates neurodegeneration in C. elegans models of Parkinson's disease.
|
Hum Mol Genet |
2015-3-1 |
Pubmed
Full text
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ショウジョウバエ
|
1009R-2
,
1009R-3
|
22705
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Puromycin-sensitive aminopeptidase protects against aggregation-prone proteins via autophagy.
|
Hum Mol Genet |
2010-12-1 |
Pubmed
Full text
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線虫
|
tm2912
|
4331
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A systematic RNAi screen reveals involvement of endocytic pathway in neuronal dysfunction in alpha-synuclein transgenic C. elegans.
|
Hum Mol Genet |
2008-10-1 |
Pubmed
Full text
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