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  • Search Condition : Filter (MeSH = eIF-2 Kinase / metabolism)
Species Resource Title
C.elegans , Human and Animal Cells tm4397 , tm1340 , tm1944 , 293T(RCB2202) ER proteostasis regulators cell-non-autonomously control sleep.
Human and Animal Cells RLC-16 The endoplasmic reticulum is a target organelle for trivalent dimethylarsinic acid (DMAIII)-induced cytotoxicity.
Human and Animal Cells ATDC5(RCB0565) Inhibiting the integrated stress response pathway prevents aberrant chondrocyte differentiation thereby alleviating chondrodysplasia.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Translational control during endoplasmic reticulum stress beyond phosphorylation of the translation initiation factor eIF2α.
C.elegans tm1153 Constitutive XBP-1s-mediated activation of the endoplasmic reticulum unfolded protein response protects against pathological tau.
DNA material rat LAP* (RDB17915) , rat active STAT5B (RDB17922) , rat LAP*T189A (RDB17933) , rat Xbp1-Luc (RDB17934) Growth hormone activates X-box binding protein 1 in a sexually dimorphic manner through the extracellular signal-regulated protein kinase and CCAAT/enhancer-binding protein β pathway in rat liver.
Human and Animal Cells HL-60(RCB3683) Mitochondrial Activity and Unfolded Protein Response are Required for Neutrophil Differentiation.
C.elegans tm794 RNF-121 is an endoplasmic reticulum-membrane E3 ubiquitin ligase involved in the regulation of beta-integrin.
C.elegans tm1153 , tm849 , tm5409 RNA surveillance is required for endoplasmic reticulum homeostasis.
C.elegans tm4525 Protective coupling of mitochondrial function and protein synthesis via the eIF2α kinase GCN-2.
Human and Animal Cells MKN45(RCB1001) , NUGC-4(RCB1939) , Kato III(RCB2088) , MRC-5 Antitumor effects of a sirtuin inhibitor, tenovin-6, against gastric cancer cells via death receptor 5 up-regulation.
Human and Animal Cells RAW 264(RCB0535) Activating transcription factor 4 links metabolic stress to interleukin-6 expression in macrophages.
Human and Animal Cells HeLaS3 The 5'-untranslated region regulates ATF5 mRNA stability via nonsense-mediated mRNA decay in response to environmental stress.
Human and Animal Cells KGN(RCB1154) , HeLa(RCB0007) Short RNA duplexes elicit RIG-I-mediated apoptosis in a cell type- and length-dependent manner.
Mice RBRC00806 Paneth cells as a site of origin for intestinal inflammation.
Yeast FY10303 , FY9930 Cellular stress induces cytoplasmic RNA granules in fission yeast.
C.elegans tm1267 , tm629 Semaphorin controls epidermal morphogenesis by stimulating mRNA translation via eIF2alpha in Caenorhabditis elegans.