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  • Search Condition : Filter (MeSH = rab GTP-Binding Proteins / genetics)
Species Resource
Yeast HM123 Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast.
Drosophila 10844R-3 , 1630R-1 , 7134R-6 , 4032R-2 , 4726R-3 , 15438R-2 , 4019R-3 , 1718R-3 , 15221R-1 , 12290R-3 , ... Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.
Yeast FY7507(L972) , FY7251(TN4) , FY7816(TN29) Two fission yeast rab7 homologs, ypt7 and ypt71, play antagonistic roles in the regulation of vacuolar morphology.
Arabidopsis / Cultured plant cells, genes pda14224 The Arabidopsis ABA-activated kinase OST1 phosphorylates the bZIP transcription factor ABF3 and creates a 14-3-3 binding site involved in its turnover.
Yeast BYP1804 The nutrient stress-induced small GTPase Rab5 contributes to the activation of vesicle trafficking and vacuolar activity.
Drosophila Rab6 Is Required for Multiple Apical Transport Pathways but Not the Basolateral Transport Pathway in Drosophila Photoreceptors.
Human and Animal Cells Impact of autophagy inhibition at different stages on cytotoxic effect of autophagy inducer in glioblastoma cells.
Yeast TN8 , TN29 The small GTPase Rab5 homologue Ypt5 regulates cell morphology, sexual development, ion-stress response and vacuolar formation in fission yeast.
Yeast genomic DNA clones Functional link between Rab GTPase-mediated membrane trafficking and PI4,5P2 signaling.
Drosophila Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells.
DNA material Slp4-a (RDB03421) , pEF-T7-mouse Slac2-b (RDB15095) , pEF-FLAG-mouse Munc18-1 (RDB15177). Slp4-a/granuphilin-a inhibits dense-core vesicle exocytosis through interaction with the GDP-bound form of Rab27A in PC12 cells.
DNA material pYO773 (RDB08752) , pNMV3 (RDB08753) , pNMV4 (RDB08754) , pGPR3 (RDB08755) , pGPR3C (RDB08756) , pGPR334 (RDB08757) , pGPR352 (RDB08758) , pGPR379 (RDB08759) , pGPR3133 (RDB08760) , pGGR3D (RDB08761) , ... Overexpression of PRA2, a Rab/Ypt-family small GTPase from Pea Pisum sativum, aggravates the growth defect of yeast ypt mutants.
C.elegans LRRK2 and RAB7L1 coordinately regulate axonal morphology and lysosome integrity in diverse cellular contexts.
C.elegans Whole-Organism Developmental Expression Profiling Identifies RAB-28 as a Novel Ciliary GTPase Associated with the BBSome and Intraflagellar Transport.
Human and Animal Cells C6(RCB2854) Characterization of Heparan Sulfate Proteoglycan-positive Recycling Endosomes Isolated from Glioma Cells.
C.elegans The small GTPase RAB-35 defines a third pathway that is required for the recognition and degradation of apoptotic cells.
Human and Animal Cells Hela SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
Drosophila Yif1 associates with Yip1 on Golgi and regulates dendrite pruning in sensory neurons during Drosophila metamorphosis.
C.elegans tm2523 EHBP-1 functions with RAB-10 during endocytic recycling in Caenorhabditis elegans.
C.elegans tm2241 TBC-2 regulates RAB-5/RAB-7-mediated endosomal trafficking in Caenorhabditis elegans.