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  • Search Condition : Filter (MeSH = rab GTP-Binding Proteins / metabolism)
Species Resource Title
C.elegans tm2241 The Rab GTPase activating protein TBC-2 regulates endosomal localization of DAF-16 FOXO and lifespan.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) , Atg7 +/+ MEFs(RCB3706) , Atg7 -/- MEFs(RCB3707) Autophagy gene ATG7 regulates albumin transcytosis in renal tubule epithelial cells.
DNA material pEGFP-C1-hUVRAG (RDB19632) , pMXs-puro-VPS34-GFP (RDB19633) , p3xFLAG-CMV10-hUVRAG (RDB19776) , pEGFP-C1-hAtg14 (RDB19785) , pMXs-IP-GFP-Atg14 (RDB19790) , pCI-neo-HA-hAtg14 (RDB19797) , pCI-neo-HA-hUVRAG (RDB19803) Beclin 1 forms two distinct phosphatidylinositol 3-kinase complexes with mammalian Atg14 and UVRAG.
DNA material pMRX-puro-3×FLAG-UACA (RDB19594) , pMRX-puro-3×FLAG-UACA-ΔANKR (RDB19595) , pMRX-puro-3×FLAG-UACA-ΔCC1 (RDB19596) , pMRX-puro-3×FLAG-UACA-ΔCC2 (RDB19597) , pMRX-puro-3×FLAG-UACA-ΔCC3 (RDB19598) , pMRX-puro-3×FLAG-UACA-ΔCC4 (RDB19599) , pMRX-puro-3×Myc-Lyspersin (RDB19600) Rab39 and its effector UACA regulate basolateral exosome release from polarized epithelial cells.
Mice RBRC04421 The lysosomal V-ATPase a3 subunit is involved in localization of Mon1-Ccz1, the GEF for Rab7, to secretory lysosomes in osteoclasts.
DNA material pMK106 (RDB08469) , pMRX-bsr-Flag-AID-Rab1B (RDB19429) , pMRX-bsr-Flag-AID-Rab5A (RDB19430) , pMRX-bsr-FLAG-OsTIR1 (RDB19431) Establishment and analysis of conditional Rab1- and Rab5-knockout cells using the auxin-inducible degron system.
C.elegans tm2526 , tm2663 An EHBP-1-SID-3-DYN-1 axis promotes membranous tubule fission during endocytic recycling.
Human and Animal Cells MDA-MB-453(RCB1192) , MCF7(RCB1904) Epigenetic regulation of ZEB1-RAB25/ESRP1 axis plays a critical role in phenylbutyrate treatment-resistant breast cancer.
Human and Animal Cells 293T(RCB2202) Functional complementation of V-ATPase a subunit isoforms in osteoclasts.
Drosophila 31935R-3 The Warburg Micro Syndrome-associated Rab3GAP-Rab18 module promotes autolysosome maturation through the Vps34 Complex I.
Arabidopsis / Cultured plant cells, genes pda Interactions between Transport Protein Particle (TRAPP) complexes and Rab GTPases in Arabidopsis.
C.elegans tm2790 , tm2907 Epidermal control of axonal attachment via β-spectrin and the GTPase-activating protein TBC-10 prevents axonal degeneration.
Drosophila DGRC#109128 Peroxisome Elevation Induces Stem Cell Differentiation and Intestinal Epithelial Repair.
Drosophila GFP-IR-1 Multiple Requirements for Rab GTPases in the Development of Drosophila Tracheal Dorsal Branches and Terminal Cells.
Drosophila DGRC#104055 , DGRC#111536 , DGRC#115285 Shot and Patronin polarise microtubules to direct membrane traffic and biogenesis of microvilli in epithelia.
Drosophila A postsynaptic PI3K-cII dependent signaling controller for presynaptic homeostatic plasticity.
DNA material pMRX-bsr-Myc-Rab2A (RDB17357) , pMRX-bsr-Myc-Rab5A (RDB17359) , pMRX-puro-EGFP-Rab6A (RDB17361) , pMRX-puro-EGFP-Rab11A (RDB17362) , pMRX-bsr-Myc-Rab2B (RDB17358) , pMRX-puro-EGFP-Rab1B (RDB17360) , pMRX-bsr-ss-EGFP-FM4 (RDB17364) , pMRX-bsr-ss-EGFP-FM4-TMD (RDB17365) , pMRX-bsr-ss-EGFP (RDB17363) Comprehensive knockout analysis of the Rab family GTPases in epithelial cells.
DNA material pEF-T7-HPS4 (RDB17366) , pEF-T7-GST-RBD32/38 (RDB17371) RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes.
Human and Animal Cells HeLa SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
Drosophila 8056R-3 , 1395R-1 An SH3PX1-Dependent Endocytosis-Autophagy Network Restrains Intestinal Stem Cell Proliferation by Counteracting EGFR-ERK Signaling.