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  • Search Condition : Filter (MeSH = rab GTP-Binding Proteins / metabolism)
Species Resource
Drosophila Drosophila Tempura, a novel protein prenyltransferase α subunit, regulates notch signaling via Rab1 and Rab11.
Drosophila Exocyst-mediated membrane trafficking is required for branch outgrowth in Drosophila tracheal terminal cells.
Drosophila tj-Gal4 (NP1624 , DGRC#104055) A Rab10-dependent mechanism for polarized basement membrane secretion during organ morphogenesis.
Yeast HM123 Loss of Apm1, the micro1 subunit of the clathrin-associated adaptor-protein-1 complex, causes distinct phenotypes and synthetic lethality with calcineurin deletion in fission yeast.
C.elegans dma-1(tm5159) , rab-8 (tm2526) , sec-5 (tm1413) , sec-10 (tm3437) , sec-5 (tm1443) RAB-10-Dependent Membrane Transport Is Required for Dendrite Arborization.
Drosophila IKKε regulates cell elongation through recycling endosome shuttling.
Drosophila 10844R-3 , 1630R-1 , 7134R-6 , 4032R-2 , 4726R-3 , 15438R-2 , 4019R-3 , 1718R-3 , 15221R-1 , 12290R-3 , ... Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes.
Yeast ? Rab-family GTPase regulates TOR complex 2 signaling in fission yeast.
Yeast MKW5 , KJ100-7B(Y) , YN68 ? A role for fission yeast Rab GTPase Ypt7p in sporulation.
DNA material pEGFP-C1-mouse Rab35 (RDB14197) , pEGFP-C1-mouse Rab35(TS/TA) (RDB14198) , pEGFP-C1-mouse Rab35(S5A) (RDB14199). Regulation of podocalyxin trafficking by Rab small GTPases in 2D and 3D epithelial cell cultures.
DNA material Slp4-a (RDB034219 , Rab27A (RDB03423). Slp4-a/granuphilin-a regulates dense-core vesicle exocytosis in PC12 cells.
Human and Animal Cells Hela SIMPLE binds specifically to PI4P through SIMPLE-like domain and participates in protein trafficking in the trans-Golgi network and/or recycling endosomes.
C.elegans tm2241 C. elegans Rab GTPase activating protein TBC-2 promotes cell corpse degradation by regulating the small GTPase RAB-5.
C.elegans tm1320 The retromer coat complex coordinates endosomal sorting and dynein-mediated transport, with carrier recognition by the trans-Golgi network.
Yeast TN8 , TN29 The small GTPase Rab5 homologue Ypt5 regulates cell morphology, sexual development, ion-stress response and vacuolar formation in fission yeast.
DNA material pYO773 (RDB08752) , pNMV3 (RDB08753) , pNMV4 (RDB08754) , pGPR3 (RDB08755) , pGPR3C (RDB08756) , pGPR334 (RDB08757) , pGPR352 (RDB08758) , pGPR379 (RDB08759) , pGPR3133 (RDB08760) , pGGR3D (RDB08761) , ... Overexpression of PRA2, a Rab/Ypt-family small GTPase from Pea Pisum sativum, aggravates the growth defect of yeast ypt mutants.
C.elegans Negative regulation of phosphatidylinositol 3-phosphate levels in early-to-late endosome conversion.
C.elegans RAB-6.1 and RAB-6.2 Promote Retrograde Transport in C. elegans.
DNA material pEF-T7-mouse Vps39 (RDB14679) , pEF-T7-mouse Vps41 (RDB14680). Genetic screen in Drosophila muscle identifies autophagy-mediated T-tubule remodeling and a Rab2 role in autophagy.
DNA material pEGFP-C1-human TBC1D1 (RDB14982) , pEGFP-C1-human TBC1D2A (RDB14983) , pEGFP-C1-human TBC1D3 (RDB14985) , pEGFP-C1-human TBC1D4 (RDB14986) , pEGFP-C1-human TBC1D5 (RDB14987) , pEGFP-C1-human TBC1D6 (RDB14988) , pEGFP-C1-human TBC1D8A (RDB14990) , pEGFP-C1-human TBC1D8B (RDB14991) , pEGFP-C1-human TBC1D9A (RDB14992) , pEGFP-C1-human TBC1D9B (RDB14993) , ... Identification of EPI64 as a GTPase-activating protein specific for Rab27A.