RRC ID 51883
Author Wu WJ, Jia WW, Liu XH, Pan LL, Zhang QY, Yang D, Shen XY, Liu L, Zhu YZ.
Title S-propargyl-cysteine attenuates inflammatory response in rheumatoid arthritis by modulating the Nrf2-ARE signaling pathway.
Journal Redox Biol
Abstract S modulator, exerted anti-inflammatory properties in RA by upregulating the Nrf2-antioxidant response element (ARE) signaling pathway.
Volume 10
Pages 157-167
Published 2016-12
DOI 10.1016/j.redox.2016.08.011
PII S2213-2317(16)30122-7
PMID 27744121
PMC PMC5066299
MeSH Animals Anti-Inflammatory Agents / administration & dosage* Anti-Inflammatory Agents / pharmacology Antioxidant Response Elements / drug effects* Arthritis, Rheumatoid / drug therapy* Arthritis, Rheumatoid / genetics Cell Line Cell Movement / drug effects Cell Survival Cysteine / administration & dosage Cysteine / analogs & derivatives* Cysteine / pharmacology Disease Models, Animal Dose-Response Relationship, Drug Humans Male NF-E2-Related Factor 2 / genetics* Rats Rats, Sprague-Dawley Reactive Oxygen Species / metabolism Signal Transduction / drug effects Up-Regulation
IF 7.126
Resource
Human and Animal Cells MH7A(RCB1512)