論文 - 詳細
| RRC ID | 61368 |
|---|---|
| 著者 | Lianbao Ye, Yuanxin Tian, Zhonghuang Li, Hong Jin, Zhengguang Zhu, Shanhe Wan, Junyan Zhang, Pengjiu Yu, Jiajie Zhang, Shuguang Wu |
| タイトル | Design, synthesis and molecular docking studies of some novel spiro[indoline-3, 4′-piperidine]-2-ones as potential c-Met inhibitors |
| ジャーナル | European Journal of Medicinal Chemistry |
| 巻・号 | 50 |
| ページ | 370-375 |
| 公開日 | 2012-4-1 |
| DOI | 10.1016/j.ejmech.2012.02.016 |
| PMID | 22381355 |
| MeSH | Binding Sites Blotting, Western Cell Proliferation / drug effects Drug Design* Drug Discovery Fluorescence Resonance Energy Transfer Humans Inhibitory Concentration 50 Models, Molecular Molecular Structure Piperidines / chemistry* Protein Kinase Inhibitors / chemical synthesis* Protein Kinase Inhibitors / pharmacology* Proto-Oncogene Proteins c-met / antagonists & inhibitors* Stomach Neoplasms / drug therapy* Stomach Neoplasms / metabolism Structure-Activity Relationship Tumor Cells, Cultured |
| IF | 5.573 |
| リソース情報 | |
| ヒト・動物細胞 | MKN45(RCB1001) |