RRC ID |
6309
|
Author |
Nakase Y, Hirata A, Shimoda C, Nakamura T.
|
Title |
Ectopic overproduction of a sporulation-specific transcription factor induces assembly of prespore-like membranous compartments in vegetative cells of fission yeast.
|
Journal |
Genetics
|
Abstract |
Mei4 is a key sporulation-specific transcription factor in fission yeast. Ectopic expression of Mei4 in vegetative cells caused formation of nucleated membranous compartments, which shared common features with normal forespore membranes, thereby perturbing nuclear division. These results suggest why expression of development-specific transcription factors must be strictly controlled.
|
Volume |
183(3)
|
Pages |
1195-9
|
Published |
2009-11-1
|
DOI |
10.1534/genetics.109.106906
|
PII |
genetics.109.106906
|
PMID |
19737749
|
PMC |
PMC2778971
|
MeSH |
Blotting, Western
Cell Compartmentation
Cell Division
Cell Membrane / metabolism*
Cell Membrane / ultrastructure
Gene Expression Regulation, Fungal
Green Fluorescent Proteins / genetics
Green Fluorescent Proteins / metabolism
Microscopy, Electron
Microscopy, Fluorescence
Mutation
Schizosaccharomyces / cytology
Schizosaccharomyces / genetics*
Schizosaccharomyces / metabolism
Schizosaccharomyces pombe Proteins / genetics*
Schizosaccharomyces pombe Proteins / metabolism
Spores, Fungal / cytology
Spores, Fungal / genetics*
Spores, Fungal / metabolism
|
IF |
4.015
|
Times Cited |
4
|
WOS Category
|
GENETICS & HEREDITY
|
Resource |
Yeast |
FY7456
FY6845
FY12104
FY12490 |