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  • Search Condition : Filter (MeSH = Adaptor Proteins, Signal Transducing / genetics)
Species Resource Title
C.elegans UNC-16 alters DLK-1 localization and negatively regulates actin and microtubule dynamics in Caenorhabditis elegans regenerating neurons.
C.elegans USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork.
Drosophila DGRC#109029 , HMS01352 , HMJ30245 , 5862R-1 A neuroprotective role of Ufmylation through Atg9 in the aging brain of Drosophila.
DNA material pEGFP-C1-hATG101 (RDB19626) , p3xFLAG-CMV10-hAtg101 (RDB19773) , pCI-neo-HA-hAtg13 (RDB19802) Atg101, a novel mammalian autophagy protein interacting with Atg13.
Human and Animal Cells ATDC5(RCB0565) Secreted frizzled-related protein 5 (SFRP5) protects ATDC5 cells against LPS-induced inflammation and apoptosis via inhibiting Wnt5a/JNK pathway.
Drosophila EGFRAP encodes a new negative regulator of the EGFR acting in both normal and oncogenic EGFR/Ras-driven tissue morphogenesis.
Human and Animal Cells 1231A3(HPS0381) Generation of NPHP1 knockout human pluripotent stem cells by a practical biallelic gene deletion strategy using CRISPR/Cas9 and ssODN.
Human and Animal Cells 293T(RCB2202) Combinations of deletion and missense variations of the dynein-2 DYNC2LI1 subunit found in skeletal ciliopathies cause ciliary defects.
Human and Animal Cells MCF7(RCB1904) , Hep G2 , 293(RCB1637) , NRK49F(RCB0112) , A549 , HeLa In Silico and In Cell Hybrid Selection of Nonrapalog Ligands to Allosterically Inhibit the Kinase Activity of mTORC1.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Human and Animal Cells RBE(RCB1292) Notch2 controls hepatocyte-derived cholangiocarcinoma formation in mice.
Human and Animal Cells NIH3T3 The Inhibitor of Apoptosis Protein Livin Confers Resistance to Fas-Mediated Immune Cytotoxicity in Refractory Lymphoma.
Zebrafish Tg(brn3a-hsp70:GFP)rw0110b Temporal control of Wnt signaling is required for habenular neuron diversity and brain asymmetry.
Arabidopsis / Cultured plant cells, genes pda14908 Structural features of the plant N-recognin ClpS1 and sequence determinants in its targets that govern substrate selection.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP)isi04 Hipk2 and PP1c cooperate to maintain Dvl protein levels required for Wnt signal transduction.
DNA material pCAGGS (RDB08938) Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF.
C.elegans tm3067 , tm7883 TALPID3 and ANKRD26 selectively orchestrate FBF1 localization and cilia gating.
C.elegans tm1416 YAP in epithelium senses gut barrier loss to deploy defenses against pathogens.
Human and Animal Cells 201B7(HPS0063) Decreased YAP activity reduces proliferative ability in human induced pluripotent stem cell of duchenne muscular dystrophy derived cardiomyocytes.
Drosophila DGRC#140400 Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis.