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  • Search Condition : Filter (MeSH = Adaptor Proteins, Signal Transducing / genetics)
Species Resource
C.elegans tm544 , tm659 , tm3515 ATX-3, CDC-48 and UBXN-5: a new trimolecular complex in Caenorhabditis elegans.
C.elegans tm1031 The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.
C.elegans tm1743 , tm544 , tm659 , tm1173 , tm1380 , tm1180 ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans.
DNA material pSVtsA58 ori (-) (RDB01126) Different initial steps of apoptosis induced by two types of antineoplastic drugs.
C.elegans tm1137 The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans.
Drosophila Elimination of oncogenic neighbors by JNK-mediated engulfment in Drosophila.
DNA material pCAhMCSF Human M-CSF (RDB01524) Physical and functional association of c-Src and adhesion and degranulation promoting adaptor protein (ADAP) in osteoclastogenesis in vitro.
C.elegans tm1060 AMPH-1/Amphiphysin/Bin1 functions with RME-1/Ehd1 in endocytic recycling.
Drosophila GS strains BTB protein, dKLHL18/CG3571, serves as an adaptor subunit for a dCul3 ubiquitin ligase complex.
Medaka HdrR-II1 (IB178) Ol4E-T, a eukaryotic translation initiation factor 4E-binding protein of medaka fish (Oryzias latipes), can interact with nanos3 and vasa in vitro.
Mice GFP-LC3#53 (RBRC00806) Phospholipase C-related catalytically inactive protein, a novel microtubule-associated protein 1 light chain 3-binding protein, negatively regulates autophagosome formation.
Arabidopsis / Cultured plant cells, genes pda08829 The Arabidopsis adaptor protein AP-3μ interacts with the G-protein β subunit AGB1 and is involved in abscisic acid regulation of germination and post-germination development.
Drosophila 11107R-2 The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses.
Drosophila The scaffolding protein Cnk binds to the receptor tyrosine kinase Alk to promote visceral founder cell specification in Drosophila.
DNA material pco12 EGFR (RDB01276) , CSII-EF-MCS (RDB04378). ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Drosophila 1462R-2 , 9968R-1 , 5562R-3 , 9148R-2 , 12918R-2 , 6223R-2 , 5862R-1 , 4164R-4 , 7225R-1 , 5112R-1 , ... A genetic screen in Drosophila for regulators of human prostate cancer progression.
Drosophila 6033R-2 , 1044R-3 DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris.
Yeast FY9899? Imp2, the PSTPIP homolog in fission yeast, affects sensitivity to the immunosuppressant FK506 and membrane trafficking in fission yeast.
Mice Emx1-Cre KI Δneo(RBRC01345) JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
Medaka MT374 (hirame) , MT364 (fukuwarai) , MT830 (OK-Cab) , WS339 (K-Kaga) YAP is essential for tissue tension to ensure vertebrate 3D body shape.