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  • Search Condition : Filter (MeSH = Adaptor Proteins, Signal Transducing / genetics)
Species Resource
Pathogenic microorganisms NA Shigella IpgB1 promotes bacterial entry through the ELMO-Dock180 machinery.
C.elegans tm1031 The adaptor-like protein ROG-1 is required for activation of the Ras-MAP kinase pathway and meiotic cell cycle progression in Caenorhabditis elegans.
C.elegans tm1743 , tm544 , tm659 , tm1173 , tm1380 , tm1180 ER E3 ubiquitin ligase HRD-1 and its specific partner chaperone BiP play important roles in ERAD and developmental growth in Caenorhabditis elegans.
DNA material pSVtsA58 ori (-) (RDB01126) Different initial steps of apoptosis induced by two types of antineoplastic drugs.
C.elegans tm1137 The ALP-Enigma protein ALP-1 functions in actin filament organization to promote muscle structural integrity in Caenorhabditis elegans.
Arabidopsis / Cultured plant cells, genes pda08829 The Arabidopsis adaptor protein AP-3μ interacts with the G-protein β subunit AGB1 and is involved in abscisic acid regulation of germination and post-germination development.
Drosophila 11107R-2 The DEAH-box RNA helicase DHX15 activates NF-κB and MAPK signaling downstream of MAVS during antiviral responses.
DNA material pco12 EGFR (RDB01276) , CSII-EF-MCS (RDB04378). ESCRT-0 protein hepatocyte growth factor-regulated tyrosine kinase substrate (Hrs) is targeted to endosomes independently of signal-transducing adaptor molecule (STAM) and the complex formation with STAM promotes its endosomal dissociation.
Drosophila 1462R-2 , 9968R-1 , 5562R-3 , 9148R-2 , 12918R-2 , 6223R-2 , 5862R-1 , 4164R-4 , 7225R-1 , 5112R-1 , ... A genetic screen in Drosophila for regulators of human prostate cancer progression.
Drosophila 6033R-2 , 1044R-3 DRK/DOS/SOS converge with Crk/Mbc/dCed-12 to activate Rac1 during glial engulfment of axonal debris.
Yeast FY9899? Imp2, the PSTPIP homolog in fission yeast, affects sensitivity to the immunosuppressant FK506 and membrane trafficking in fission yeast.
Mice Emx1-Cre KI Δneo(RBRC01345) JSAP1/JIP3 and JLP regulate kinesin-1-dependent axonal transport to prevent neuronal degeneration.
DNA material CS-CDF-CG-PRE (RDB04379) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Knockdown of synapse-associated protein Dlg1 reduces syncytium formation induced by human T-cell leukemia virus type 1.
Drosophila Ex vivo genome-wide RNAi screening of the Drosophila Toll signaling pathway elicited by a larva-derived tissue extract.
Human and Animal Cells The Keap1/Nrf2 protein axis plays a role in osteoclast differentiation by regulating intracellular reactive oxygen species signaling.
Human and Animal Cells Association of p62/SQSTM1 excess and oral carcinogenesis.
Human and Animal Cells Establishment of new intraperitoneal paclitaxel-resistant gastric cancer cell lines and comprehensive gene expression analysis.
Human and Animal Cells Identification of the 12q15 amplicon within the homogeneously staining regions in the embryonal rhabdomyosarcoma cell line RMS-YM.
Human and Animal Cells microRNA 31 functions as an endometrial cancer oncogene by suppressing Hippo tumor suppressor pathway.
Human and Animal Cells Phenylalanine sensitive K562-D cells for the analysis of the biochemical impact of excess amino acid.