Species
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Resource
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RRC ID
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Title
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Journal
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Published
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Link
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DNA material
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pET28/His6-mCherry-NT-Lys (RDB13499)
,
pET28/His6-EGFP-NT-Lys (RDB13498)
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76886
|
The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells.
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Nat Cell Biol |
2023-8-1 |
Pubmed
Full text
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C.elegans
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tm3425
|
76088
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Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans.
|
Nat Commun |
2021-8-20 |
Pubmed
Full text
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Drosophila
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|
70814
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Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress.
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Cell Rep |
2021-4-13 |
Pubmed
Full text
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Human and Animal Cells
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HCE-T(RCB2280)
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68569
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Lipidomic analysis of epithelial corneal cells following hyperosmolarity and benzalkonium chloride exposure: New insights in dry eye disease.
|
Biochim Biophys Acta Mol Cell Biol Lipids |
2020-9-1 |
Pubmed
Full text
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Human and Animal Cells
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THP-1(RCB1189)
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65765
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Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells.
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J Radiat Res |
2017-9-1 |
Pubmed
Full text
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Human and Animal Cells
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B16
,
SK-MEL-28(RCB1930)
|
65534
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WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
|
Biochem Biophys Res Commun |
2017-9-16 |
Pubmed
Full text
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Human and Animal Cells
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CACO-2(RCB0988)
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63864
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Structure-dependent absorption of atypical sphingoid long-chain bases from digestive tract into lymph.
|
Lipids Health Dis |
2021-3-1 |
Pubmed
Full text
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Human and Animal Cells
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MDCK(RCB0995)
|
61316
|
Cellular Uptake of Clostridium botulinum C2 Toxin Requires Acid Sphingomyelinase Activity.
|
Infect Immun |
2017-4-1 |
Pubmed
Full text
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Human and Animal Cells
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A549(RCB0098)
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58784
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Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
|
Biochim Biophys Acta Mol Cell Biol Lipids |
2020-6-1 |
Pubmed
Full text
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Human and Animal Cells
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ST2(RCB0224)
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54754
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Ceramide kinase regulates the migration of bone marrow-derived mesenchymal stem cells.
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Biochem Biophys Res Commun |
2019-1-8 |
Pubmed
Full text
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Drosophila
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DGRC#105467
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47654
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A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
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Neurobiol Dis |
2017-2-1 |
Pubmed
Full text
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Human and Animal Cells
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B16 melanoma
|
44339
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A small molecule inhibitor of Bcl-2, HA14-1, also inhibits ceramide glucosyltransferase.
|
Biochem Biophys Res Commun |
2013-4-5 |
Pubmed
Full text
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Human and Animal Cells
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PC-12(RCB0009)
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42042
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Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis.
|
Neurochem Int |
2004-4-1 |
Pubmed
Full text
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Human and Animal Cells
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MEB4(RCB1027)
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42014
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N-butyldeoxynojirimycin inhibits murine melanoma cell ganglioside metabolism and delays tumor onset.
|
Cancer Lett |
2003-11-10 |
Pubmed
Full text
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Human and Animal Cells
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COS-7(RCB0539)
,
CHO-K1(RCB0285)
|
41517
|
Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.
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J Biol Chem |
2002-5-17 |
Pubmed
Full text
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Human and Animal Cells
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MKN45(RCB1001)
,
J774.1(RCB0434)
|
39933
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Distinct mechanism of Helicobacter pylori-mediated NF-kappa B activation between gastric cancer cells and monocytic cells.
|
J Biol Chem |
2001-11-30 |
Pubmed
Full text
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Mice
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RBRC01828
|
22711
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Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
|
Mol Cell Biol |
2013-7-1 |
Pubmed
Full text
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Drosophila
|
|
15395
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A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration.
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PLoS One |
2011-11-1 |
Pubmed
Full text
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Cellular slime molds
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|
6744
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(Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1.
|
Mol Cancer Res |
2007-8-1 |
Pubmed
Full text
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C.elegans
|
tm1027
,
tm1097
,
tm1192
,
tm504
|
5850
|
Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells.
|
J Cell Sci |
2009-3-15 |
Pubmed
Full text
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