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  • Search Condition : Filter (MeSH = Ceramides / metabolism)
Species Resource Title
DNA material pET28/His6-mCherry-NT-Lys (RDB13499) , pET28/His6-EGFP-NT-Lys (RDB13498) The formation of migrasomes is initiated by the assembly of sphingomyelin synthase 2 foci at the leading edge of migrating cells.
C.elegans tm3425 Saturated very long chain fatty acid configures glycosphingolipid for lysosome homeostasis in long-lived C. elegans.
Drosophila Dihydroceramide desaturase regulates the compartmentalization of Rac1 for neuronal oxidative stress.
Human and Animal Cells HCE-T(RCB2280) Lipidomic analysis of epithelial corneal cells following hyperosmolarity and benzalkonium chloride exposure: New insights in dry eye disease.
Human and Animal Cells THP-1(RCB1189) Involvement of reactive oxygen species in ionizing radiation-induced upregulation of cell surface Toll-like receptor 2 and 4 expression in human monocytic cells.
Human and Animal Cells B16 , SK-MEL-28(RCB1930) WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
Human and Animal Cells CACO-2(RCB0988) Structure-dependent absorption of atypical sphingoid long-chain bases from digestive tract into lymph.
Human and Animal Cells MDCK(RCB0995) Cellular Uptake of Clostridium botulinum C2 Toxin Requires Acid Sphingomyelinase Activity.
Human and Animal Cells A549(RCB0098) Inhibitory effects of ceramide kinase on Rac1 activation, lamellipodium formation, cell migration, and metastasis of A549 lung cancer cells.
Human and Animal Cells ST2(RCB0224) Ceramide kinase regulates the migration of bone marrow-derived mesenchymal stem cells.
Drosophila DGRC#105467 A saposin deficiency model in Drosophila: Lysosomal storage, progressive neurodegeneration and sensory physiological decline.
Human and Animal Cells B16 melanoma A small molecule inhibitor of Bcl-2, HA14-1, also inhibits ceramide glucosyltransferase.
Human and Animal Cells PC-12(RCB0009) Crocin prevents the death of PC-12 cells through sphingomyelinase-ceramide signaling by increasing glutathione synthesis.
Human and Animal Cells MEB4(RCB1027) N-butyldeoxynojirimycin inhibits murine melanoma cell ganglioside metabolism and delays tumor onset.
Human and Animal Cells COS-7(RCB0539) , CHO-K1(RCB0285) Importance of C1B domain for lipid messenger-induced targeting of protein kinase C.
Human and Animal Cells MKN45(RCB1001) , J774.1(RCB0434) Distinct mechanism of Helicobacter pylori-mediated NF-kappa B activation between gastric cancer cells and monocytic cells.
Mice RBRC01828 Impaired epidermal permeability barrier in mice lacking elovl1, the gene responsible for very-long-chain fatty acid production.
Drosophila A suppressor/enhancer screen in Drosophila reveals a role for wnt-mediated lipid metabolism in primordial germ cell migration.
Cellular slime molds (Dihydro)ceramide synthase 1 regulated sensitivity to cisplatin is associated with the activation of p38 mitogen-activated protein kinase and is abrogated by sphingosine kinase 1.
C.elegans tm1027 , tm1097 , tm1192 , tm504 Expression of ceramide glucosyltransferases, which are essential for glycosphingolipid synthesis, is only required in a small subset of C. elegans cells.