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  • Search Condition : Filter (MeSH = DNA Damage / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 NB69(RCB0480) Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death.
ヒト・動物細胞 KP4(RCB1005) MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
原核生物(大腸菌) ME10048 , ME10052 , ME10053 , ME10054 Roles of replicative and specialized DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains lacking one or all of SOS-inducible DNA polymerases to 26 chemicals.
酵母 FY20991 Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.
線虫 tm3507 , tm370 THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans.
線虫 tm2176 , tm2181 Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.
線虫 tm764 , tm3724 , tm1203 , tm750 , tm1524 , tm2026 , tm3157 , tm5027 , tm3886 Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals.
酵母 Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
ヒト・動物細胞 HCT116(RCB2979) , CHO-K1(RCB0285) , HCT116-XRCC4(-/-)(RCB2981) , NIH3T3 Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
ヒト・動物細胞 K562(RCB0027) Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
原核生物(大腸菌) Cell Lysis Directed by SulA in Response to DNA Damage in Escherichia coli.
ヒト・動物細胞 201B7(HPS0063) DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
ヒト・動物細胞 JHOC-5(RCB1520) , JHOC-9(RCB2226) High Expression of p21 as a Potential Therapeutic Target in Ovarian Clear-cell Carcinoma.
ヒト・動物細胞 NB1RGB(RCB0222) Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase.
線虫 tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
線虫 tm3948 , tm3425 , tm1226 , tm10601 , tm6801 Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
ショウジョウバエ The role of DNA repair genes in radiation-induced adaptive response in Drosophila melanogaster is differential and conditional.
酵母 FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
ショウジョウバエ DGRC#109116 PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
線虫 tm6691 , tm4374 , tm2862 , tm2572 UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.