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  • Search Condition : Filter (MeSH = DNA Damage / genetics)
Species Resource Title
Human and Animal Cells NB69(RCB0480) Polycomb group protein BMI1 protects neuroblastoma cells against DNA damage-induced apoptotic cell death.
Human and Animal Cells KP4(RCB1005) MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
Prokaryotes E. coli ME10048 , ME10052 , ME10053 , ME10054 Roles of replicative and specialized DNA polymerases in frameshift mutagenesis: mutability of Salmonella typhimurium strains lacking one or all of SOS-inducible DNA polymerases to 26 chemicals.
Yeast FY20991 Comprehensive mutational analysis of the checkpoint signaling function of Rpa1/Ssb1 in fission yeast.
C.elegans tm3507 , tm370 THSC/TREX-2 deficiency causes replication stress and genome instability in Caenorhabditis elegans.
C.elegans tm2176 , tm2181 Histone demethylase AMX-1 is necessary for proper sensitivity to interstrand crosslink DNA damage.
C.elegans tm764 , tm3724 , tm1203 , tm750 , tm1524 , tm2026 , tm3157 , tm5027 , tm3886 Efficient collection of a large number of mutations by mutagenesis of DNA damage response defective animals.
Yeast Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
Human and Animal Cells HCT116(RCB2979) , CHO-K1(RCB0285) , HCT116-XRCC4(-/-)(RCB2981) , NIH3T3 Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
Human and Animal Cells K562(RCB0027) Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
Prokaryotes E. coli Cell Lysis Directed by SulA in Response to DNA Damage in Escherichia coli.
Human and Animal Cells 201B7(HPS0063) DNA damage in embryonic neural stem cell determines FTLDs' fate via early-stage neuronal necrosis.
Human and Animal Cells JHOC-5(RCB1520) , JHOC-9(RCB2226) High Expression of p21 as a Potential Therapeutic Target in Ovarian Clear-cell Carcinoma.
Human and Animal Cells NB1RGB(RCB0222) Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase.
C.elegans tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
C.elegans tm3948 , tm3425 , tm1226 , tm10601 , tm6801 Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
Drosophila The role of DNA repair genes in radiation-induced adaptive response in Drosophila melanogaster is differential and conditional.
Yeast FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
Drosophila DGRC#109116 PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
C.elegans tm6691 , tm4374 , tm2862 , tm2572 UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.