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  • 35 Hits
  • Search Condition : Filter (MeSH = DNA Damage / genetics)
Species Resource Title
Human and Animal Cells HCT116(RCB2979) Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
Human and Animal Cells K562(RCB0027) Telomerase overexpression in K562 leukemia cells protects against apoptosis by serum deprivation and double-stranded DNA break inducing agents, but not against DNA synthesis inhibitors.
Prokaryotes E. coli Cell Lysis Directed by SulA in Response to DNA Damage in Escherichia coli.
Human and Animal Cells JHOC-5(RCB1520) , JHOC-9(RCB2226) High Expression of p21 as a Potential Therapeutic Target in Ovarian Clear-cell Carcinoma.
Human and Animal Cells NB1RGB(RCB0222) Xeroderma pigmentosum variant: from a human genetic disorder to a novel DNA polymerase.
C.elegans tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
C.elegans tm3948 , tm3425 , tm1226 , tm10601 , tm6801 Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
Drosophila The role of DNA repair genes in radiation-induced adaptive response in Drosophila melanogaster is differential and conditional.
Yeast FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
Drosophila DGRC#109116 PARylation regulates stress granule dynamics, phase separation, and neurotoxicity of disease-related RNA-binding proteins.
C.elegans tm6691 , tm4374 , tm2862 , tm2572 UNG-1 and APN-1 are the major enzymes to efficiently repair 5-hydroxymethyluracil DNA lesions in C. elegans.
C.elegans tm5027 ATM Induces Cell Death with Autophagy in Response to H2O2 Specifically in Caenorhabditis elegans Nondividing Cells.
C.elegans tm1779 , tm1108 Nonselective autophagy reduces mitochondrial content during starvation in Caenorhabditis elegans.
Human and Animal Cells WI-38(RCB0702) d-amino acid oxidase promotes cellular senescence via the production of reactive oxygen species.
C.elegans tm1661 Intermittent Stem Cell Cycling Balances Self-Renewal and Senescence of the C. elegans Germ Line.
Human and Animal Cells Hep G2(RCB1886) Multiple-endpoints gene alteration-based (MEGA) assay: A toxicogenomics approach for water quality assessment of wastewater effluents.
C.elegans tm1145 , tm2026 , tm2842 , tm2940 Caenorhabditis elegans BUB-3 and SAN-1/MAD3 Spindle Assembly Checkpoint Components Are Required for Genome Stability in Response to Treatment with Ionizing Radiation.
Prokaryotes E. coli JW3622-KC Escherichia coli DNA ligase B may mitigate damage from oxidative stress.
C.elegans tm3735 JMJD-5/KDM8 regulates H3K36me2 and is required for late steps of homologous recombination and genome integrity.
DNA material S. pombe ORFeome clone SpYFH27F12 (SPW090932) , SpYFH45G09 (SPW098153). Phosphorylation-dependent interactions between Crb2 and Chk1 are essential for DNA damage checkpoint.