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  • 検索条件 : 絞込み (MeSH = DNA Helicases / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 NIH:OVCAR-3(RCB2135) Ovarian high-grade serous carcinoma cells with low SMARCA4 expression and high SMARCA2 expression contribute to platinum resistance.
遺伝子材料 CSIV-TRE-RfA-UbC-KT (RDB12878) The ribonuclease domain function is dispensable for SLFN11 to mediate cell fate decision during replication stress response.
線虫 tm1200 The conserved helicase ZNFX-1 memorializes silenced RNAs in perinuclear condensates.
線虫 tm4063 , tm6139 The CHARGE syndrome ortholog CHD-7 regulates TGF-β pathways in Caenorhabditis elegans.
酵母 FY23931 , FY16386 , FY25693 Smc5/6 Complex Promotes Rad3ATR Checkpoint Signaling at the Perturbed Replication Fork through Sumoylation of the RecQ Helicase Rqh1.
ヒト・動物細胞 KhES-1(HES0001) , 201B7(HPS0063) Improving the differentiation potential of pluripotent stem cells by optimizing culture conditions.
酵母 FY13012(TK7) RecQ DNA Helicase Rqh1 Promotes Rad3ATR Kinase Signaling in the DNA Replication Checkpoint Pathway of Fission Yeast.
酵母 FY11064(MY3141) , FY10067(MY2167) Expression of the cancer-associated DNA polymerase ε P286R in fission yeast leads to translesion synthesis polymerase dependent hypermutation and defective DNA replication.
ヒト・動物細胞 HEV0190 CDCA7 and HELLS suppress DNA:RNA hybrid-associated DNA damage at pericentromeric repeats.
原核生物(大腸菌) Insufficient levels of the nrdAB-encoded ribonucleotide reductase underlie the severe growth defect of the Δhda E. coli strain.
線虫 tm1489 C. elegans orthologs MUT-7/CeWRN-1 of Werner syndrome protein regulate neuronal plasticity.
線虫 tm1200 , tm1860 A Small-RNA-Mediated Feedback Loop Maintains Proper Levels of 22G-RNAs in C. elegans.
ヒト・動物細胞 HuH-7(RCB1366) , Hep G2(RCB1886) Decreased Expression of Fructose-1,6-bisphosphatase Associates with Glucose Metabolism and Tumor Progression in Hepatocellular Carcinoma.
ヒト・動物細胞 HSC-3(RCB1975) , HSC-4(RCB1902) , SAS(RCB1974) HEATR1, a novel interactor of Pontin/Reptin, stabilizes Pontin/Reptin and promotes cell proliferation of oral squamous cell carcinoma.
酵母 Yeast strain containing ADH1-osTIR1-2-9myc @ ura3, from Nishimura et al, Nat Methods 2009 The capacity of origins to load MCM establishes replication timing patterns.
酵母 FY20933 , FY8155 Bioinformatical dissection of fission yeast DNA replication origins.
線虫 tm5021 , tm892 A DNA repair protein and histone methyltransferase interact to promote genome stability in the Caenorhabditis elegans germ line.
遺伝子材料 , ヒト・動物細胞 CS-RfA-EVBsd (RDB06090) , pENTR4-H1 (RDB04395) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , ATN-1(RCB1440) Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.
遺伝子材料 , ヒト・動物細胞 p3XFLAG-CDCA7 WT (RDB17374) , p3XFLAG-CDCA7 R274C (RDB17375) , p3XFLAG-HELLS WT (RDB17376) , p3XFLAG-HELLS Q699R (RDB17377) , DNMT3B px330 (RDB17378) , ZBTB24 px330 (RDB17379) , CDCA7 px330 (RDB17380) , HELLS px330 (RDB17381) , Ku80 px330 (RDB17382) , HEV0190 CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome.
原核生物(大腸菌) MG1655 Genome-wide relationship between R-loop formation and antisense transcription in Escherichia coli.