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  • Search Condition : Filter (MeSH = Histone Deacetylases / genetics)
Species Resource Title
Human and Animal Cells MIA Paca2(RCB2094) , PANC-1(RCB2095) FOXO3a Activation by HDAC Class IIa Inhibition Induces Cell Cycle Arrest in Pancreatic Cancer Cells.
Drosophila DGRC#120052 , HMC03086 Schlank orchestrates insect developmental transition by switching H3K27 acetylation to trimethylation in the prothoracic gland.
Human and Animal Cells HS-SY-II(RCB2231) The fusion protein SS18-SSX1 employs core Wnt pathway transcription factors to induce a partial Wnt signature in synovial sarcoma.
C.elegans tm2807 , tm2927 Forward genetic screening identifies novel roles for N-terminal acetyltransferase C and histone deacetylase in C. elegans development.
Human and Animal Cells iPS-MEF-Fb/Ng-440A-3(APS0003) HDAC8 is implicated in embryoid body formation via canonical Hedgehog signaling and regulates neuronal differentiation.
Arabidopsis / Cultured plant cells, genes pda00244 , pda03349 , pda08977 , pda13390 Plant-specific HDT family histone deacetylases are nucleoplasmins.
Yeast BY4848 RPD3 and UME6 are involved in the activation of PDR5 transcription and pleiotropic drug resistance in ρ0 cells of Saccharomyces cerevisiae.
Human and Animal Cells KP4(RCB1005) SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy.
Human and Animal Cells HS-SY-II(RCB2231) Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma.
Human and Animal Cells HuH-7 Downregulation of AZGP1 by Ikaros and histone deacetylase promotes tumor progression through the PTEN/Akt and CD44s pathways in hepatocellular carcinoma.
Yeast Rbm10 facilitates heterochromatin assembly via the Clr6 HDAC complex.
Human and Animal Cells ATDC5(RCB0565) MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression.
DNA material , Mice CSII-EF-MCS (RDB04378) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , RBRC01830 Repression of Somatic Genes by Selective Recruitment of HDAC3 by BLIMP1 Is Essential for Mouse Primordial Germ Cell Fate Determination.
Human and Animal Cells NB-1(RCB1953) A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment.
Human and Animal Cells ATDC5(RCB0565) MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation.
C.elegans tm2322 , tm1703 The small GTPases ARL-13 and ARL-3 coordinate intraflagellar transport and ciliogenesis.
C.elegans tm2217 Invasive Cell Fate Requires G1 Cell-Cycle Arrest and Histone Deacetylase-Mediated Changes in Gene Expression.
Human and Animal Cells U937 HDAC4 mediates development of hypertension via vascular inflammation in spontaneous hypertensive rats.
DNA material CSIV-CMV-MCS-IRES2-Venus (RDB08257) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). MEF2D-BCL9 Fusion Gene Is Associated With High-Risk Acute B-Cell Precursor Lymphoblastic Leukemia in Adolescents.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) The novel orally active proteasome inhibitor K-7174 exerts anti-myeloma activity in vitro and in vivo by down-regulating the expression of class I histone deacetylases.