生物種
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リソース名
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RRC ID
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タイトル
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ジャーナル
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公開日
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外部リンク
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メダカ
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fli::GFP (TG1206)
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69688
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Effects of a novel selective PPARα modulator, statin, sodium-glucose cotransporter 2 inhibitor, and combinatorial therapy on the liver and vasculature of medaka nonalcoholic steatohepatitis model.
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Biochem Biophys Res Commun |
2022-3-12 |
Pubmed
Full text
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ヒト・動物細胞
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Hepa 1-6(RCB1638)
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68704
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γ-Tocotrienol attenuates triglyceride through effect on lipogenic gene expressions in mouse hepatocellular carcinoma Hepa 1-6.
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J Nutr Sci Vitaminol (Tokyo) |
2013-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB1886)
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67439
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Pravastatin Modulate Niemann-Pick C1-Like 1 and ATP-Binding Cassette G5 and G8 to Influence Intestinal Cholesterol Absorption.
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J Pharm Pharm Sci |
2015-1-1 |
Pubmed
Full text
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ヒト・動物細胞
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HL60(RCB0041)
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U937
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65834
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Statins induce apoptosis through inhibition of Ras signaling pathways and enhancement of Bim and p27 expression in human hematopoietic tumor cells.
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Tumour Biol |
2017-10-1 |
Pubmed
Full text
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ヒト・動物細胞
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HuCCT1(RCB1960)
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YSCCC(RCB1549)
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64023
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Statins induce apoptosis and inhibit proliferation in cholangiocarcinoma cells.
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Int J Oncol |
2011-9-1 |
Pubmed
Full text
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ヒト・動物細胞
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SSP-25(RCB1293)
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HuH-28(RCB1943)
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61794
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Lovastatin overcomes gefitinib resistance through TNF-α signaling in human cholangiocarcinomas with different LKB1 statuses in vitro and in vivo.
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Oncotarget |
2015-9-15 |
Pubmed
Full text
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ヒト・動物細胞
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MC3T3-E1(RCB1126)
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61790
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Lipophilic statins can be osteogenic by promoting osteoblastic calcification in a Cbfa1- and BMP-2-independent manner.
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Methods Find Exp Clin Pharmacol |
2001-9-1 |
Pubmed
Full text
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ヒト・動物細胞
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ST2(RCB0224)
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61400
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Bisphosphonate- and statin-induced enhancement of OPG expression and inhibition of CD9, M-CSF, and RANKL expressions via inhibition of the Ras/MEK/ERK pathway and activation of p38MAPK in mouse bone marrow stromal cell line ST2.
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Mol Cell Endocrinol |
2012-9-25 |
Pubmed
Full text
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ヒト・動物細胞
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Ca9-22(RCB1976)
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51919
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The sensitivity of head and neck carcinoma cells to statins is related to the expression of their Ras expression status, and statin-induced apoptosis is mediated via suppression of the Ras/ERK and Ras/mTOR pathways.
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Clin Exp Pharmacol Physiol |
2017-2-1 |
Pubmed
Full text
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ヒト・動物細胞
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43881
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Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance.
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J Appl Physiol (1985) |
2012-8-1 |
Pubmed
Full text
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ヒト・動物細胞
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43288
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The possibility of simvastatin as a chemotherapeutic agent for all-trans retinoic acid-resistant promyelocytic leukemia.
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Biol Pharm Bull |
2008-3-1 |
Pubmed
Full text
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ヒト・動物細胞
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Hep G2(RCB0459)
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42246
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Pitavastatin, a potent hydroxymethylglutaryl coenzyme a reductase inhibitor, increases cholesterol 7 alpha-hydroxylase gene expression in HepG2 cells.
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Circ J |
2004-11-1 |
Pubmed
Full text
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ヒト・動物細胞
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38564
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Hydrophobic statins induce autophagy and cell death in human rhabdomyosarcoma cells by depleting geranylgeranyl diphosphate.
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Eur J Pharmacol |
2012-1-15 |
Pubmed
Full text
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ヒト・動物細胞
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Jurkat(RCB0806)
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J774
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38475
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HMG-CoA reductase inhibitors enhance phagocytosis by upregulating ATP-binding cassette transporter A7.
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Atherosclerosis |
2011-8-1 |
Pubmed
Full text
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線虫
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tm4368
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36636
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The mitochondrial unfolded protein response activator ATFS-1 protects cells from inhibition of the mevalonate pathway.
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Proc Natl Acad Sci U S A |
2013-4-9 |
Pubmed
Full text
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ヒト・動物細胞
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MLC-6(RCB1536)
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19152
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Simvastatin inhibits osteoclast differentiation induced by bone morphogenetic protein-2 and RANKL through regulating MAPK, AKT and Src signaling.
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Regul Pept |
2010-6-8 |
Pubmed
Full text
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実験動物マウス
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RBRC01390
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6059
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Simvastatin lowers reactive oxygen species level by Nrf2 activation via PI3K/Akt pathway.
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Biochem Biophys Res Commun |
2010-5-28 |
Pubmed
Full text
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ヒト・動物細胞
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MC3T3-E1(RCB1126)
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1380
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Statins inhibit osteoblast migration by inhibiting Rac-Akt signaling.
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Biochem Biophys Res Commun |
2004-3-12 |
Pubmed
Full text
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