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  • Search Condition : Filter (MeSH = Jumonji Domain-Containing Histone Demethylases / genetics)
Species Resource Title
Human and Animal Cells Lu-165(RCB1184) SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
DNA material Genome Network Project Human cDNA Clone IRAL004L19 (HGY081883) JMJD2A sensitizes gastric cancer to chemotherapy by cooperating with CCDC8.
C.elegans jmjd-1.2(tm3713) JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress.
C.elegans tm3525 SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network.
Human and Animal Cells The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Human and Animal Cells COLO205(RCB2127) , COLO-320(RCB1193) , LoVo(RCB1639) The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer.
C.elegans tm3136 and tm3118 The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.
Zebrafish rw0130a(Tg (Huc:Kaede)) KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.