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  • Search Condition : Filter (MeSH = Jumonji Domain-Containing Histone Demethylases / metabolism*)
Species Resource Title
Human and Animal Cells MCF7(RCB1904) , 293T(RCB2202) SCF(Fbxo22)-KDM4A targets methylated p53 for degradation and regulates senescence.
DNA material Genome Network Project Human cDNA Clone IRAL004L19 (HGY081883) JMJD2A sensitizes gastric cancer to chemotherapy by cooperating with CCDC8.
C.elegans jmjd-1.2(tm3713) JMJD-1.2 controls multiple histone post-translational modifications in germ cells and protects the genome from replication stress.
C.elegans tm3713 JMJD-1.2/PHF8 controls axon guidance by regulating Hedgehog-like signaling.
C.elegans tm3525 SLR-2 and JMJC-1 regulate an evolutionarily conserved stress-response network.
C.elegans tm2966 , tm1624 , tm853 , tm1489 Conserved antagonism between JMJD2A/KDM4A and HP1γ during cell cycle progression.
Human and Animal Cells The histone demethylase JMJD2B plays an essential role in human carcinogenesis through positive regulation of cyclin-dependent kinase 6.
Human and Animal Cells COLO205(RCB2127) , COLO-320(RCB1193) , LoVo(RCB1639) The Prognostic Significance of Histone Lysine Demethylase JMJD3/KDM6B in Colorectal Cancer.
Zebrafish rw0130a(Tg (Huc:Kaede)) KDM7 is a dual demethylase for histone H3 Lys 9 and Lys 27 and functions in brain development.
C.elegans tm3713 Coordinated regulation of active and repressive histone methylations by a dual-specificity histone demethylase ceKDM7A from Caenorhabditis elegans.