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  • Search Condition : Filter (MeSH = Leupeptins / pharmacology)
Species Resource Title
Human and Animal Cells ST2(RCB0224) Mechanisms involved in suppression of osteoclast supportive activity by transforming growth factor-β1 via the ubiquitin-proteasome system.
Human and Animal Cells Atg5^(-/-)MEF(RCB2711) The endoplasmic reticulum-residing chaperone BiP is short-lived and metabolized through N-terminal arginylation.
DNA material Genome Network Project Human cDNA , IRAL021H13 (HGY088581) , IRAK004A12 (HGX001612) S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.
DNA material pFLAG-CMV-5a-RPL23 (RDB17324) , pGEX6P-1-RPL23 (RDB17325) , pET-28a-RPL23 (RDB17326) , pCLH'CX-His-T7-RPL23 (RDB17327) , pCMV-GRWD1 (RDB17328) GRWD1 regulates ribosomal protein L23 levels via the ubiquitin-proteasome system.
Drosophila 4097R–1 , 4097R-2 Proteasome activity determines pupation timing through the degradation speed of timer molecule Blimp-1.
Human and Animal Cells MDA-MB-453(RCB1192) , MCF7(RCB1904) Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.
DNA material pMXs-Puro-Flag-mouse CNOT3 full length (RDB14289) , pMXs-Puro-Flag-mouseCNOT3 (1-606) (RDB14290) , pMXs-Puro-Flag-mouse CNOT3 (245-end) (RDB14291). CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins.
Human and Animal Cells F-36P(RCB0775) Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
Human and Animal Cells MCF7(RCB1904) Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells.
Human and Animal Cells NB1RGB(RCB0222) , HGC-27(RCB0500) Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells.
Human and Animal Cells Differential regulation of eotaxin-1/CCL11 and eotaxin-3/CCL26 production by the TNF-alpha and IL-4 stimulated human lung fibroblast.
Human and Animal Cells Involvement of calpain in melanogenesis of mouse B16 melanoma cells.
Human and Animal Cells TGF-beta1 enhances degradation of IFN-gamma-induced iNOS protein via proteasomes in RAW 264.7 cells.
Human and Animal Cells EoL-1 cell(RCB0641) Tumour necrosis factor-alpha-induced expression of intercellular adhesion molecule-1 on human eosinophilic leukaemia EoL-1 cells is mediated by the activation of nuclear factor-kappaB pathway.
Human and Animal Cells HSP90 is crucial for regulation of LAT expression in activated T cells.
General Microbes JCM 1612 Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells.
Arabidopsis / Cultured plant cells, genes rpc00001 Environmental stresses induce misfolded protein aggregation in plant cells in a microtubule-dependent manner.
Human and Animal Cells RAW 264(RCB0535) Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.
Yeast NA The Ubiquitin ligase Ubr11 is essential for oligopeptide utilization in the fission yeast Schizosaccharomyces pombe.
Xenopus tropicalis Tbx6, Thylacine1, and E47 synergistically activate bowline expression in Xenopus somitogenesis.