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  • Search Condition : Filter (MeSH = Leupeptins / pharmacology)
Species Resource
Yeast BY22828 The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.
Xenopus tropicalis Tbx6, Thylacine1, and E47 synergistically activate bowline expression in Xenopus somitogenesis.
Arabidopsis / Cultured plant cells, genes rpc00001 Environmental stresses induce misfolded protein aggregation in plant cells in a microtubule-dependent manner.
General Microbes JCM 1612 Candida albicans and Candida parapsilosis rapidly up-regulate galectin-3 secretion by human gingival epithelial cells.
Drosophila 4097R–1 , 4097R-2 Proteasome activity determines pupation timing through the degradation speed of timer molecule Blimp-1.
DNA material pMXs-Puro-Flag-mouse CNOT3 full length (RDB14289) , pMXs-Puro-Flag-mouseCNOT3 (1-606) (RDB14290) , pMXs-Puro-Flag-mouse CNOT3 (245-end) (RDB14291). CNOT3 suppression promotes necroptosis by stabilizing mRNAs for cell death-inducing proteins.
Rats Involvement of Ca2+-dependent proteasome in the degradation of both cyclin B1 and Mos during spontaneous activation of matured rat oocytes.
Arabidopsis / Cultured plant cells, genes rpc00008 The 26S proteasome function and Hsp90 activity involved in the regulation of HsfA2 expression in response to oxidative stress.
Yeast NA The Ubiquitin ligase Ubr11 is essential for oligopeptide utilization in the fission yeast Schizosaccharomyces pombe.
Human and Animal Cells Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells.
Human and Animal Cells Cbl negatively regulates erythropoietin-induced growth and survival signaling through the proteasomal degradation of Src kinase.
Human and Animal Cells HepG2(RCB1886) , ATDC5(RCB0565) Molecular hydrogen suppresses activated Wnt/β-catenin signaling.
Human and Animal Cells MDA-MB-453(RCB1192) , MCF7(RCB1904) Down-Regulation of Ca2+-Activated K⁺ Channel KCa1.1 in Human Breast Cancer MDA-MB-453 Cells Treated with Vitamin D Receptor Agonists.
Human and Animal Cells HSP90 is crucial for regulation of LAT expression in activated T cells.
Human and Animal Cells RAW 264 (RCB0535) Thalidomide inhibits lipopolysaccharide-induced tumor necrosis factor-alpha production via down-regulation of MyD88 expression.
Human and Animal Cells Proteasome inhibitors remarkably prevent translesion replication in cancer cells but not normal cells.
Human and Animal Cells C2C12 , MC3T3-E1 SOCS-2 interferes with myotube formation and potentiates osteoblast differentiation through upregulation of JunB in C2C12 cells.
Human and Animal Cells Tumour necrosis factor-alpha-induced expression of intercellular adhesion molecule-1 on human eosinophilic leukaemia EoL-1 cells is mediated by the activation of nuclear factor-kappaB pathway.
Human and Animal Cells TGF-beta1 enhances degradation of IFN-gamma-induced iNOS protein via proteasomes in RAW 264.7 cells.
Human and Animal Cells Involvement of calpain in melanogenesis of mouse B16 melanoma cells.