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  • Search Condition : Filter (MeSH = Liver X Receptors)
Species Resource
Human and Animal Cells CACO-2 Dominant expression of ATP-binding cassette transporter-1 on basolateral surface of Caco-2 cells stimulated by LXR/RXR ligands.
Human and Animal Cells RAW 264 Verapamil increases the apolipoprotein-mediated release of cellular cholesterol by induction of ABCA1 expression via Liver X receptor-independent mechanism.
Human and Animal Cells RAW 264 , BALB/3T3 clone A31 Fenofibric acid, an active form of fenofibrate, increases apolipoprotein A-I-mediated high-density lipoprotein biogenesis by enhancing transcription of ATP-binding cassette transporter A1 gene in a liver X receptor-dependent manner.
Human and Animal Cells Hep G2 A possible mechanism for atherosclerosis induced by polycyclic aromatic hydrocarbons.
Human and Animal Cells Dual roles of nuclear receptor liver X receptor α (LXRα) in the CYP3A4 expression in human hepatocytes as a positive and negative regulator.
Human and Animal Cells 7-Dehydrocholesterol metabolites produced by sterol 27-hydroxylase (CYP27A1) modulate liver X receptor activity.
Human and Animal Cells The RXR agonists PA024 and HX630 have different abilities to activate LXR/RXR and to induce ABCA1 expression in macrophage cell lines.
Human and Animal Cells A naturally occurring rexinoid, honokiol, can serve as a regulator of various retinoid x receptor heterodimers.
Human and Animal Cells Retinoic acid receptor agonists regulate expression of ATP-binding cassette transporter G1 in macrophages.
Human and Animal Cells Differential expression and function of alternative splicing variants of human liver X receptor α.
Human and Animal Cells Astaxanthin enhances ATP-binding cassette transporter A1/G1 expressions and cholesterol efflux from macrophages.
Human and Animal Cells Identification of endocrine disrupting chemicals activating SXR-mediated transactivation of CYP3A and CYP7A1.
Human and Animal Cells Liver X receptor α bidirectionally transactivates human CYP1A1 and CYP1A2 through two cis-elements common to both genes.
DNA material CS-CDF-CG-PRE (RDB04379) , CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). Characterization of actions of octanoate on porcine preadipocytes and adipocytes differentiated in vitro.
Human and Animal Cells THP-1 (RCB1189) Pioglitazone enhances cholesterol efflux from macrophages by increasing ABCA1/ABCG1 expressions via PPARγ/LXRα pathway: findings from in vitro and ex vivo studies.
Human and Animal Cells FGF-1 induces expression of LXRalpha and production of 25-hydroxycholesterol to upregulate the apoE gene in rat astrocytes.
Mice Nrf2 knockout mouse/C57BL6J Nrf2 inhibits LXRα-dependent hepatic lipogenesis by competing with FXR for acetylase binding.
Human and Animal Cells HepG2 Human cytochrome P450 1A1 is a novel target gene of liver X receptor α.
Human and Animal Cells Transport-metabolism interplay: LXRalpha-mediated induction of human ABC transporter ABCC2 (cMOAT/MRP2) in HepG2 cells.
DNA material pGL4-phSESN2 (RDB07413) Resveratrol inhibits LXRα-dependent hepatic lipogenesis through novel antioxidant Sestrin2 gene induction.