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  • Search Condition : Filter (MeSH = MAP Kinase Signaling System / genetics)
Species Resource Title
Mice RBRC00999 Expression of kinase-deficient MEK2 ameliorates Pelizaeus-Merzbacher disease phenotypes in mice.
Human and Animal Cells Human dermal fibroblasts Promotion of squamous cell carcinoma tumorigenesis by oncogene-mediated THG-1/TSC22D4 phosphorylation.
Human and Animal Cells 293(RCB1637) , G-361(RCB0991) , A549(RCB3677) , T24(RCB2536) , A431(RCB0202) , PANC-1(RCB2095) , HCT116(RCB2979) , 293gp(RCB2354) Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.
Human and Animal Cells HuH-7 , Hep G2(RCB1648) Identification of interleukin-16 production on tumor aggravation in hepatocellular carcinoma by a proteomics approach.
Drosophila DGRC#111740 Distinct roles of Bendless in regulating FSC niche competition and daughter cell differentiation.
Human and Animal Cells PC-12(RCB0009) Erinacine C Activates Transcription from a Consensus ETS DNA Binding Site in Astrocytic Cells in Addition to NGF Induction.
Human and Animal Cells MMAc·SF(RCB1200) Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells.
Human and Animal Cells MKN7(RCB0999) , MKN45(RCB1001) , MKN74(RCB1002) , Kato III(RCB2088) Enhanced expression of the M2 isoform of pyruvate kinase is involved in gastric cancer development by regulating cancer-specific metabolism.
Human and Animal Cells HFL-I(RCB0521) Exosome-Derived microRNA-22 Ameliorates Pulmonary Fibrosis by Regulating Fibroblast-to-Myofibroblast Differentiation in Vitro and in Vivo.
C.elegans tm797 N-Glycosylation of the Discoidin Domain Receptor Is Required for Axon Regeneration in Caenorhabditis elegans.
Drosophila DGRC#104055 EGFR Signaling Stimulates Autophagy to Regulate Stem Cell Maintenance and Lipid Homeostasis in the Drosophila Testis.
Drosophila 5183R-1 , 5183R-2 , 4322R-1 , 4780R-3 , 4780R-1 , 9668R-2 , 31640R-3 , 7000R-2 , 9668R-1 , 7227R-1 , ... An in vivo RNAi screen uncovers the role of AdoR signaling and adenosine deaminase in controlling intestinal stem cell activity.
Human and Animal Cells A172(RCB2530) The cystine/glutamate antiporter xCT is a key regulator of EphA2 S897 phosphorylation under glucose-limited conditions.
Drosophila 7788R-1 , 7788R-2 , 5370R-2 Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression.
Drosophila DGRC#111872 JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress.
Drosophila 2275R-1 , 2262R-1 JNK signaling coordinates with ecdysone signaling to promote pruning of Drosophila sensory neuron dendrites.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) EphA2 phosphorylation at Ser897 by the Cdk1/MEK/ERK/RSK pathway regulates M-phase progression via maintenance of cortical rigidity.
Human and Animal Cells HCE-T(RCB2280) Mechanistic role of transglutaminase-2 in focal adhesions.
Drosophila 12217R-2 PpV, acting via the JNK pathway, represses apoptosis during normal development of Drosophila wing.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) Composite regulation of ERK activity dynamics underlying tumour-specific traits in the intestine.