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  • Search Condition : Filter (MeSH = Microtubule-Associated Proteins / genetics)
Species Resource
Drosophila Ku70 alleviates neurodegeneration in Drosophila models of Huntington's disease.
Drosophila A homeostatic clock sets daughter centriole size in flies.
C.elegans tm5597 , tm1447 PTRN-1/CAMSAP promotes CYK-1/formin-dependent actin polymerization during endocytic recycling.
Human and Animal Cells HTC/C3(RCB0452) Mitosis perturbation by MASTL depletion impairs the viability of thyroid tumor cells.
C.elegans tm6474 , tm2508 , tm3425 Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
Arabidopsis / Cultured plant cells, genes pda08293 , pda13397 Cell cycle-regulated PLEIADE/AtMAP65-3 links membrane and microtubule dynamics during plant cytokinesis.
DNA material Xpa (RDB15264) , Xpa H62Q (RDB15265). A diffraction-quality protein crystal processed as an autophagic cargo.
DNA material mKeima (h)/pCS2 (RDB15236) , dKeima (h)/pCS2 (RDB15237) , mt-mKeima (h)/pIND(SP1) (RDB15238) , mt-mKeima/pcDNA3 (RDB15456). A sensitive and quantitative technique for detecting autophagic events based on lysosomal delivery.
DNA material pcDNA3/hArf1(WT)-mCherry (RDB15345) , pcDNA3/hArf3-mCherry (RDB15346) , pcDNA3/hArf5(WT)-mCherry (RDB15347) , pEGFP-N3/hArf5(WT)-EGFP (RDB15348) , pcDNA3/hArf6(WT)-HA (RDB15349) , pcDNA3/hArf6(Q67L)-HA (RDB15350) , pcDNA3/hArf6(T27N)-HA (RDB15351) , pcDNA3/hArf6(WT)-mCherry (RDB15352) , pEGFP-N3/hArf6(WT)-EGFP (RDB15353). Structural basis for Arf6-MKLP1 complex formation on the Flemming body responsible for cytokinesis.
Mice C57BL/6N-Sqstm1/Rbrc(RBRC03941) Sqstm1-GFP knock-in mice reveal dynamic actions of Sqstm1 during autophagy and under stress conditions in living cells.
DNA material pEGFP-C1-Mreg (RDB15182) Melanoregulin regulates retrograde melanosome transport through interaction with the RILP-p150Glued complex in melanocytes.
Mice GFP-LC3#53(RBRC00806) ATG4B inhibitors with a benzotropolone core structure block autophagy and augment efficiency of chemotherapy in mice.
DNA material pMRX-IP-GFP-LC3-RFP-LC3 delta G (RDB14600) , pMRX-IP-GFP-LC3-RFP (RDB14601). An Autophagic Flux Probe that Releases an Internal Control.
Mice GFP-LC3#53(RBRC00806) AMBRA1, a novel α-synuclein-binding protein, is implicated in the pathogenesis of multiple system atrophy.
C.elegans tm3489 The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans.
C.elegans tm3425 , tm3077 Autophagy activity contributes to programmed cell death in Caenorhabditis elegans.
C.elegans tm5597 PTRN-1, a microtubule minus end-binding CAMSAP homolog, promotes microtubule function in Caenorhabditis elegans neurons.
C.elegans tm5597 The Caenorhabditis elegans microtubule minus-end binding homolog PTRN-1 stabilizes synapses and neurites.
C.elegans tm3489 , tm5755 , tm2253 The C. elegans LC3 acts downstream of GABARAP to degrade autophagosomes by interacting with the HOPS subunit VPS39.
C.elegans tm1900 Phosphorylation of LC3 by the Hippo kinases STK3/STK4 is essential for autophagy.