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  • Search Condition : Filter (MeSH = Neoplasms / genetics)
Species Resource
DNA material pSTAT RE-TK hRluc(F) (RDB05616) , pISRE-TK hRluc(F) (RDB05610) , pGAS RE-TK hRluc(F) (RDB05624). Chondromodulin-1 directly suppresses growth of human cancer cells.
DNA material hTRAIL/pMKITneo human TRAIL cDNA (RDB02934) Human CD34+ cells engineered to express membrane-bound tumor necrosis factor-related apoptosis-inducing ligand target both tumor cells and tumor vasculature.
DNA material pCAG-HIVgp (RDB04394) pCMV-VSV-G-RSV-Rev (RDB04393) The RNA silencing technology applied by lentiviral vectors in oncology.
Drosophila 3722R-1 , 3722R-2 E-cadherin prolongs the moment for interaction between intestinal stem cell and its progenitor cell to ensure Notch signaling in adult Drosophila midgut.
Drosophila 10161R-2 , 10289R-1 , 10289R-1 , 10289R-1 , 10289R-2 , 10415R-3 , 10415R-3 , 10444R-1 , 10444R-2 , 10444R-2 , ... A combined ex vivo and in vivo RNAi screen for notch regulators in Drosophila reveals an extensive notch interaction network.
Drosophila Disruption of lysosome function promotes tumor growth and metastasis in Drosophila.
DNA material pMX-puro-hJHDM1D-AS1 (RDB15920). Long Noncoding RNA JHDM1D-AS1 Promotes Tumor Growth by Regulating Angiogenesis in Response to Nutrient Starvation.
Prokaryotes E. coli Holliday junction trap shows how cells use recombination and a junction-guardian role of RecQ helicase.
DNA material pFLAG-CMV-5a-RPL5 (RDB17329) , pFLAG-CMV-5a-RPL11 (RDB17330) GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
C.elegans tm4376 C. elegans FOG-3/Tob can either promote or inhibit germline proliferation, depending on gene dosage and genetic context.
C.elegans tm2697 METT-10, a putative methyltransferase, inhibits germ cell proliferative fate in Caenorhabditis elegans.
DNA material CSII-EF-MCS (RDB04378) Cell cycle-dependent Rho GTPase activity dynamically regulates cancer cell motility and invasion in vivo.
Drosophila 1081R-2 , 5092R-2 Loss of PI3K blocks cell-cycle progression in a Drosophila tumor model.
DNA material pFLAG-CMV-2-WT-human Akt1 (RDB06614) , pFLAG-CMV-2-WT-human Akt2 (RDB06615) , pFLAG-CMV-2-WT-human Akt3 (RDB06616) Casein kinase 2-interacting protein-1, a novel Akt pleckstrin homology domain-interacting protein, down-regulates PI3K/Akt signaling and suppresses tumor growth in vivo.
Drosophila Genetic models of apoptosis-induced proliferation decipher activation of JNK and identify a requirement of EGFR signaling for tissue regenerative responses in Drosophila.
Drosophila Minibrain and Wings apart control organ growth and tissue patterning through down-regulation of Capicua.
DNA material pCAcc-Luc+ (RDB02443) Polyplex micelle installing intracellular self-processing functionalities without free catiomers for safe and efficient systemic gene therapy through tumor vasculature targeting.
Human and Animal Cells HeLa/Fucci(HeLa.S-Fucci)(RCB2812) Comparative cell cycle transcriptomics reveals synchronization of developmental transcription factor networks in cancer cells.
Human and Animal Cells Suppression of metastasis by mirtazapine via restoration of the Lin-7C/β-catenin pathway in human cancer cells.
Human and Animal Cells Reprogramming suppresses premature senescence phenotypes of Werner syndrome cells and maintains chromosomal stability over long-term culture.