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  • Search Condition : Filter (MeSH = Oxidation-Reduction / drug effects)
Species Resource Title
Human and Animal Cells HCT116(RCB2979) Dual pharmacological inhibition of glutathione and thioredoxin systems synergizes to kill colorectal carcinoma stem cells.
Human and Animal Cells PC-12(RCB0009) Contribution of DHA diols (19,20-DHDP) produced by cytochrome P450s and soluble epoxide hydrolase to the beneficial effects of DHA supplementation in the brains of rotenone-induced rat models of Parkinson's disease.
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , HSC-4(RCB1902) Vasodilator oxyfedrine inhibits aldehyde metabolism and thereby sensitizes cancer cells to xCT-targeted therapy.
Human and Animal Cells B16F10(RCB2630) Citric acid promoted melanin synthesis in B16F10 mouse melanoma cells, but inhibited it in human epidermal melanocytes and HMV-II melanoma cells via the GSK3β/β-catenin signaling pathway.
Human and Animal Cells StromaNKtert(RCB2350) Serine-70 phosphorylated Bcl-2 prevents oxidative stress-induced DNA damage by modulating the mitochondrial redox metabolism.
Human and Animal Cells PC-12(RCB0009) Bisphenol A and rotenone induce S-nitrosylation of protein disulfide isomerase (PDI) and inhibit neurite outgrowth of primary cultured cells of the rat hippocampus and PC12 cells.
Human and Animal Cells 143B/TK^(-)neo^(R)(RCB0701) Ascorbate sensitizes human osteosarcoma cells to the cytostatic effects of cisplatin.
DNA material Genome Network Project Human cDNA , IRAL021H13 (HGY088581) , IRAK004A12 (HGX001612) S-Nitrosylation at the active site decreases the ubiquitin-conjugating activity of ubiquitin-conjugating enzyme E2 D1 (UBE2D1), an ERAD-associated protein.
Arabidopsis / Cultured plant cells, genes pst15755 Activation of Mitochondrial Protein Phosphatase SLP2 by MIA40 Regulates Seed Germination.
C.elegans tm3574 The glutathione reductase GSR-1 determines stress tolerance and longevity in Caenorhabditis elegans.
C.elegans tm2034 Toxic role of K+ channel oxidation in mammalian brain.
C.elegans tm351 , tm1037 Dopamine signaling regulates fat content through β-oxidation in Caenorhabditis elegans.
Human and Animal Cells Macrophage recognition of thiol-group oxidized cells: recognition of carbohydrate chains by macrophage surface nucleolin as apoptotic cells.
Human and Animal Cells Flavangenol (pine bark extract) and its major component procyanidin B1 enhance fatty acid oxidation in fat-loaded models.
Human and Animal Cells B16 murine melanoma The bystander effect is a novel mechanism of UVA-induced melanogenesis.
Human and Animal Cells A redox-silent analogue of tocotrienol inhibits hypoxic adaptation of lung cancer cells.
Human and Animal Cells RAW 264(RCB0535) Beta-carotene modulates the immunological function of RAW264, a murine macrophage cell line, by enhancing the level of intracellular glutathione.
Human and Animal Cells Effects of a novel gaseous antioxidative system containing a rosemary extract on the oxidation induced by nitrogen dioxide and ultraviolet radiation.
Human and Animal Cells Dihydro-alpha-lipoic acid has more potent cytotoxicity than alpha-lipoic acid.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394). A mitochondrial thioredoxin-sensitive mechanism regulates TGF-β-mediated gene expression associated with epithelial-mesenchymal transition.