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  • Search Condition : Filter (MeSH = Peptides, Cyclic / pharmacology*)
Species Resource Title
Human and Animal Cells HL60(RCB0041) Apicidin, a histone deacetylase inhibitor, induces differentiation of HL-60 cells.
Human and Animal Cells Hep G2(RCB0459) Stimulation of apolipoprotein E secretion in human hepatoma Hep G2 cells by a cyclic acylpeptide, N-4909.
Silkworms Serum apolipoprotein A-I potentiates the therapeutic efficacy of lysocin E against Staphylococcus aureus.
Pathogenic eukaryotic microorganisms Trichophyton mentagrophytes IFM 40996 Nicrophorusamides A and B, Antibacterial Chlorinated Cyclic Peptides from a Gut Bacterium of the Carrion Beetle Nicrophorus concolor.
Human and Animal Cells BALL-1(RCB0256) Stevastelins, a novel group of immunosuppressants, inhibit dual-specificity protein phosphatases.
Silkworms Silkworm fungal infection model for identification of virulence genes in pathogenic fungus and screening of novel antifungal drugs.
Silkworms Discovery of a new antifungal agent ASP2397 using a silkworm model of Aspergillus fumigatus infection.
Silkworms Advantage and issue of silkworm model for development of anti-infective agents.
Human and Animal Cells A431(RCB0202) Inhibition of EGFR Activation by Bivalent Ligands Based on a Cyclic Peptide Mimicking the Dimerization Arm Structure of EGFR.
Human and Animal Cells Mechanism for the decrease in the FIP1L1-PDGFRalpha protein level in EoL-1 cells by histone deacetylase inhibitors.
Human and Animal Cells Mechanism for the differentiation of EoL-1 cells into eosinophils by histone deacetylase inhibitors.
Human and Animal Cells THP-1(RCB1189) Candin family antifungal agent micafungin (FK463) modulates the inflammatory cytokine production stimulated by lipopolysaccharide in THP-1 cells.
Human and Animal Cells OST(RCB0454) FR901228 induces tumor regression associated with induction of Fas ligand and activation of Fas signaling in human osteosarcoma cells.
Human and Animal Cells SP2/0-Ag14(RCB0209) Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.
Silkworms Identification of lysocin E using a silkworm model of bacterial infection.
Silkworms Lysocin E is a new antibiotic that targets menaquinone in the bacterial membrane.
DNA material , General Microbes Genomic DNA of Pyrococcus furiosus JCM 8422T (JGD07704) , JCM 8422 A macrocyclic peptide that serves as a cocrystallization ligand and inhibits the function of a MATE family transporter.
General Microbes JCM 3347 The hydrophobicity in a chemically modified side-chain of cysteine residues of thanatin is related to antimicrobial activity against Micrococcus luteus.
DNA material , Yeast pDUAL-FFH1c (RDB06142) , S. pombe ORFeome Clones. Marine antifungal theonellamides target 3beta-hydroxysterol to activate Rho1 signaling.
Pathogenic microorganisms IFM 48313 , IFM 49832 , IFM 51757 , IFM 52112 The efficiency of the benzothiazole APB, the echinocandin micafungin, and amphotericin B in fluconazole-resistant Candida albicans and Candida dubliniensis.