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  • Search Condition : Filter (MeSH = Protein Phosphatase 1 / genetics)
Species Resource
Arabidopsis / Cultured plant cells, genes pda02740 Identification and characterization of AtI-2, an Arabidopsis homologue of an ancient protein phosphatase 1 (PP1) regulatory subunit.
Drosophila PNUTS/PP1 regulates RNAPII-mediated gene expression and is necessary for developmental growth.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
C.elegans tm1857 , tm3655 , tm1791 LAB-1 targets PP1 and restricts Aurora B kinase upon entrance into meiosis to promote sister chromatid cohesion.
C.elegans tm1647 Sperm development and motility are regulated by PP1 phosphatases in Caenorhabditis elegans.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) Transgene integration into the human AAVS1 locus enhances myosin II-dependent contractile force by reducing expression of myosin binding subunit 85.
Human and Animal Cells Regulated interaction of protein phosphatase 1 and protein phosphatase 2A with phospholipase C-related but catalytically inactive protein.