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  • 検索条件 : 絞込み (MeSH = Protein Tyrosine Phosphatases / genetics)
生物種 リソース名 タイトル
ヒト・動物細胞 SHP1^(-) DT40(RCB1466) , SHP1^(-)/SHP2^(-) DT40(RCB1501) , SHP2^(-) DT40(RCB1502) , SHIP^(-) DT40(RCB1465) Src homology 2 domain-containing protein-tyrosine phosphatases, SHP-1 and SHP-2, are required for platelet endothelial cell adhesion molecule-1/CD31-mediated inhibitory signaling.
ショウジョウバエ DGRC#142132 , DGRC#112951 Phosphatase of Regenerating Liver-1 Selectively Times Circadian Behavior in Darkness via Function in PDF Neurons and Dephosphorylation of TIMELESS.
ショウジョウバエ DGRC#202239 Condition-dependent functional shift of two Drosophila Mtmr lipid phosphatases in autophagy control.
ヒト・動物細胞 GCIY(RCB0555) , Kato III(RCB2088) , MKN74(RCB1002) , NUGC-4(RCB1939) Therapeutic potential of PRL-3 targeting and clinical significance of PRL-3 genomic amplification in gastric cancer.
ヒト・動物細胞 RAW 264(RCB0535) , COS-7(RCB0539) A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
カイコ A mitochondrial phosphatase PTPMT1 is essential for the early development of silkworm, Bombyx mori.
酵母 Clp1p and Mid1p form links between cell cycle progression and gene expression at cytokinesis in fission yeast.
ヒト・動物細胞 Sawano(RCB1152) Growth-suppressive effects of BPOZ and EGR2, two genes involved in the PTEN signaling pathway.
線虫 tm6122 Endogenous siRNAs promote proteostasis and longevity in germline-less Caenorhabditis elegans.
線虫 tm1734 Lineage context switches the function of a C. elegans Pax6 homolog in determining a neuronal fate.
ショウジョウバエ DGRC#102398 WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
線虫 tm1523 Wnt signalling requires MTM-6 and MTM-9 myotubularin lipid-phosphatase function in Wnt-producing cells.
線虫 tm591 Six and Eya promote apoptosis through direct transcriptional activation of the proapoptotic BH3-only gene egl-1 in Caenorhabditis elegans.
線虫 tm853 Regulation of Caenorhabditis elegans p53/CEP-1-dependent germ cell apoptosis by Ras/MAPK signaling.
ヒト・動物細胞 Glucose enhances protein tyrosine phosphatase 1B gene transcription in hepatocytes.
ヒト・動物細胞 BHK-21(RCB1423) Essential domain of receptor tyrosine phosphatase beta (RPTPbeta) for interaction with Helicobacter pylori vacuolating cytotoxin.
ヒト・動物細胞 Hep G2(RCB0459) Negative regulation of Fas-mediated apoptosis by FAP-1 in human cancer cells.
ショウジョウバエ The role of Bro1- domain-containing protein Myopic in endosomal trafficking of Wnt/Wingless.
酵母 NA The protein phosphatase Siw14 controls caffeine-induced nuclear localization and phosphorylation of Gln3 via the type 2A protein phosphatases Pph21 and Pph22 in Saccharomyces cerevisiae.
酵母 NA Functionally redundant protein phosphatase genes PTP2 and MSG5 co-regulate the calcium signaling pathway in Saccharomyces cerevisiae upon exposure to high extracellular calcium concentration.