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  • 検索条件 : 絞込み (MeSH = Protein-Tyrosine Kinases / genetics)
生物種 リソース名 タイトル
酵母 Fission yeast Wee1 is required for stable kinetochore-microtubule attachment.
線虫 TOP-2 is differentially required for the proper maintenance of the cohesin subunit REC-8 on meiotic chromosomes in Caenorhabditis elegans spermatogenesis and oogenesis.
線虫 tm1848 Neuropeptidergic regulation of compulsive ethanol seeking in C. elegans.
ヒト・動物細胞 Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
ヒト・動物細胞 PC-9(RCB4455) MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements.
遺伝子材料 pMXs-IP-EGFP-hFIP200 (RDB19623) , pMXs-IP-EGFP-mAtg5 (RDB19634) , p3xFLAG-CMV10-hFIP200 (RDB19762) , pMXs-IP-EGFP-ULK1(K46N) (RDB19780) , pMXs-IP-EGFP-LC3 (RDB19798) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
ヒト・動物細胞 KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
ヒト・動物細胞 ATDC5(RCB0565) CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1.
ヒト・動物細胞 Ba/F3(RCB0805) TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
ゼブラフィッシュ RIKEN WT Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord.
ヒト・動物細胞 HuCCT1(RCB1960) , TFK-1(RCB2537) Inhibition of ATR Increases the Sensitivity to WEE1 Inhibitor in Biliary Tract Cancer.
ヒト・動物細胞 HuH-7 Forced expression of DYRK2 exerts anti-tumor effects via apoptotic induction in liver cancer.
線虫 tm3084 A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in C. elegans.
ヒト・動物細胞 Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
ショウジョウバエ Screening and Analysis of Janelia FlyLight Project Enhancer-Gal4 Strains Identifies Multiple Gene Enhancers Active During Hematopoiesis in Normal and Wasp-Challenged Drosophila Larvae.
ショウジョウバエ DGRC#102398 WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
線虫 tm290 Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42-SID-3/ACK1 pathway.
ヒト・動物細胞 293T(RCB2202) Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Heat shock-induced mitotic arrest requires heat shock protein 105 for the activation of spindle assembly checkpoint.
ショウジョウバエ breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.