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  • 検索条件 : 絞込み (MeSH = Protein-Tyrosine Kinases / genetics)
生物種 リソース名 タイトル
酵母 Fission yeast Wee1 is required for stable kinetochore-microtubule attachment.
線虫 TOP-2 is differentially required for the proper maintenance of the cohesin subunit REC-8 on meiotic chromosomes in Caenorhabditis elegans spermatogenesis and oogenesis.
線虫 tm1848 Neuropeptidergic regulation of compulsive ethanol seeking in C. elegans.
ヒト・動物細胞 Ba/F3 NVL-520 Is a Selective, TRK-Sparing, and Brain-Penetrant Inhibitor of ROS1 Fusions and Secondary Resistance Mutations.
ヒト・動物細胞 PC-9(RCB4455) , MRC-5 MET kinase inhibitor reverses resistance to entrectinib induced by hepatocyte growth factor in tumors with NTRK1 or ROS1 rearrangements.
遺伝子材料 pMXs-IP-EGFP-hFIP200 (RDB19623) , pMXs-IP-EGFP-mAtg5 (RDB19634) , p3xFLAG-CMV10-hFIP200 (RDB19762) , pMXs-IP-EGFP-ULK1(K46N) (RDB19780) , pMXs-IP-EGFP-LC3 (RDB20244) FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells.
ヒト・動物細胞 KU-YS(RCB1318) , SK-N-SH(RCB0426) , TNB1(RCB0481) , KP-N-NS(RCB0687) Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.
ヒト・動物細胞 ATDC5(RCB0565) CDC5L promotes early chondrocyte differentiation and proliferation by modulating pre-mRNA splicing of SOX9, COL2A1, and WEE1.
ヒト・動物細胞 Ba/F3(RCB0805) TKI-addicted ROS1-rearranged cells are destined to survival or death by the intensity of ROS1 kinase activity.
ゼブラフィッシュ RIKEN WT , SAIGFF213A Phosphorylation of Dpsyl2 (CRMP2) and Dpsyl3 (CRMP4) is required for positioning of caudal primary motor neurons in the zebrafish spinal cord.
ヒト・動物細胞 HuCCT1(RCB1960) , TFK-1(RCB2537) Inhibition of ATR Increases the Sensitivity to WEE1 Inhibitor in Biliary Tract Cancer.
ヒト・動物細胞 HuH-7 Forced expression of DYRK2 exerts anti-tumor effects via apoptotic induction in liver cancer.
線虫 tm3084 A Receptor Tyrosine Kinase Plays Separate Roles in Sensory Integration and Associative Learning in C. elegans.
ヒト・動物細胞 Ba/F3 The new-generation selective ROS1/NTRK inhibitor DS-6051b overcomes crizotinib resistant ROS1-G2032R mutation in preclinical models.
ショウジョウバエ Screening and Analysis of Janelia FlyLight Project Enhancer-Gal4 Strains Identifies Multiple Gene Enhancers Active During Hematopoiesis in Normal and Wasp-Challenged Drosophila Larvae.
ショウジョウバエ DGRC#102398 WASH phosphorylation balances endosomal versus cortical actin network integrities during epithelial morphogenesis.
線虫 tm290 Actin organization and endocytic trafficking are controlled by a network linking NIMA-related kinases to the CDC-42-SID-3/ACK1 pathway.
ヒト・動物細胞 293T(RCB2202) Combined effect of cabozantinib and gefitinib in crizotinib-resistant lung tumors harboring ROS1 fusions.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Heat shock-induced mitotic arrest requires heat shock protein 105 for the activation of spindle assembly checkpoint.
ショウジョウバエ breathless, a Drosophila FGF receptor homolog, is essential for migration of tracheal and specific midline glial cells.