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  • 26 Hits
  • Search Condition : Filter (MeSH = Pyrroles / pharmacology*)
Species Resource Title
Pathogenic eukaryotic microorganisms Trichophyton mentagrophytes IFM 40997 Bromopyrrole Alkaloids from the Sponge Agelas kosrae.
Human and Animal Cells HMV-II(RCB0777) Combined inhibition of NF-κB and Bcl-2 triggers synergistic reduction of viability and induces apoptosis in melanoma cells.
Human and Animal Cells PC-12(RCB0009) , SK-N-SH(RCB0426) Sunitinib inhibits catecholamine synthesis and secretion in pheochromocytoma tumor cells by blocking VEGF receptor 2 via PLC-γ-related pathways.
Human and Animal Cells Hep G2(RCB1648) , HuH-7(RCB1942) Effects of Pyrrole-Imidazole Polyamides Targeting Human TGF-β1 on the Malignant Phenotypes of Liver Cancer Cells.
Human and Animal Cells LAG(RCB2758) , LM8(RCB1450) , NFSa Y83(RCB0282) , KUM5(RCB2322) CSF1/CSF1R Signaling Inhibitor Pexidartinib (PLX3397) Reprograms Tumor-Associated Macrophages and Stimulates T-cell Infiltration in the Sarcoma Microenvironment.
Human and Animal Cells PC-9(RCB4455) Discovery of 1-{(3R,4R)-3-[({5-Chloro-2-[(1-methyl-1H-pyrazol-4-yl)amino]-7H-pyrrolo[2,3-d]pyrimidin-4-yl}oxy)methyl]-4-methoxypyrrolidin-1-yl}prop-2-en-1-one (PF-06459988), a Potent, WT Sparing, Irreversible Inhibitor of T790M-Containing EGFR Mutants.
Human and Animal Cells TE-6(RCB1950) , TE-9(RCB1988) , TE-11(RCB2100) , TE-14(RCB2101) PI3Kα inhibitors sensitize esophageal squamous cell carcinoma to radiation by abrogating survival signals in tumor cells and tumor microenvironment.
Prokaryotes E. coli JW5503, JD17464 New N-phenylpyrrolamide DNA gyrase B inhibitors: Optimization of efficacy and antibacterial activity.
Human and Animal Cells Ca9-22(RCB1976) CAY10591, a SIRT1 activator, suppresses cell growth, invasion, and migration in gingival epithelial carcinoma cells.
Human and Animal Cells 201B7(HPS0063) A synthetic DNA-binding inhibitor of SOX2 guides human induced pluripotent stem cells to differentiate into mesoderm.
Pathogenic microorganisms NA Nagelamides K and L, dimeric bromopyrrole alkaloids from sponge Agelas species.
Pathogenic microorganisms NA Nagelamides X-Z, dimeric bromopyrrole alkaloids from a marine sponge Agelas sp.
Pathogenic microorganisms ? Bromopyrrole alkaloids from a marine sponge Agelas sp.
Human and Animal Cells Lu99(RCB1900) ZFC3H1, a zinc finger protein, modulates IL-8 transcription by binding with celastramycin A, a potential immune suppressor.
Human and Animal Cells B16 melanoma 4A5(RCB0557) Dimeric pyrrolidinoindoline-type alkaloids with melanogenesis inhibitory activity in flower buds of Chimonanthus praecox.
Human and Animal Cells PC-12(RCB0009) Inhibition of autophagy enhances sunitinib-induced cytotoxicity in rat pheochromocytoma PC12 cells.
Human and Animal Cells Coenzyme Q10 reverses mitochondrial dysfunction in atorvastatin-treated mice and increases exercise endurance.
Human and Animal Cells MRC-5 , NHSF46(RCB0162) Sequence-specific alkylation of double-strand human telomere repeat sequence by pyrrole-imidazole polyamides with indole linkers.
Human and Animal Cells PC-12(RCB0009) BE-18591 as a new H(+)/Cl(-) symport ionophore that inhibits immunoproliferation and gastritis.
Human and Animal Cells HL60(RCB0041) Cycloprodigiosin hydrochloride, H(+)/CL(-) symporter, induces apoptosis and differentiation in HL-60 cells.