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  • 45 Hits
  • Search Condition : Filter (MeSH = STAT3 Transcription Factor / metabolism)
Species Resource Title
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , Ca9-22(RCB1976) PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
Human and Animal Cells XTC-YF(RCB0771) Xenopus laevis il11ra.L is an experimentally proven interleukin-11 receptor component that is required for tadpole tail regeneration.
Human and Animal Cells PC-9(RCB4455) Lack of AKT activation in lung cancer cells with EGFR mutation is a novel marker of cetuximab sensitivity.
Human and Animal Cells MKN45(RCB1001) , MKN74(RCB1002) Interleukin-6 mediates epithelial-stromal interactions and promotes gastric tumorigenesis.
Human and Animal Cells HSC-2(RCB1945) ERK-dependent IL-6 autocrine signaling mediates adaptive resistance to pan-PI3K inhibitor BKM120 in head and neck squamous cell carcinoma.
Human and Animal Cells HeLa(RCB0007) , HSC-3(RCB1975) , OS-RC-2(RCB0735) miRNA-1246 in extracellular vesicles secreted from metastatic tumor induces drug resistance in tumor endothelial cells.
Human and Animal Cells B16 , SK-MEL-28(RCB1930) WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
Human and Animal Cells MKN45(RCB1001) Curcumin induces the differentiation of myeloid-derived suppressor cells and inhibits their interaction with cancer cells and related tumor growth.
Human and Animal Cells ATDC5(RCB0565) A dual role for NOTCH signaling in joint cartilage maintenance and osteoarthritis.
Human and Animal Cells ST2(RCB0224) Activation of Shc1 Allows Oncostatin M to Induce RANKL and Osteoclast Formation More Effectively Than Leukemia Inhibitory Factor.
Human and Animal Cells Hep G2, HuH-7 Hepatic Stellate Cells Contribute to the Tumor Malignancy of Hepatocellular Carcinoma Through the IL-6 Pathway.
Human and Animal Cells Ba/F3-CL1(RCB4474) Essential thrombocytosis attributed to JAK2-T875N germline mutation.
Human and Animal Cells HeLa Discovery of a New STAT3 Inhibitor Acting on the Linker Domain.
Human and Animal Cells THP-1(RCB1189) Clinical and functional significance of STEAP4-splice variant in CD14+ monocytes in patients with rheumatoid arthritis.
Cord blood stem cells for research The use of leukemia inhibitory factor immobilized on virus-derived polyhedra to support the proliferation of mouse embryonic and induced pluripotent stem cells.
Human and Animal Cells C2C12(RCB0987) Caffeine-stimulated muscle IL-6 mediates alleviation of non-alcoholic fatty liver disease.
DNA material pMY-FLAG-mouse IkB-zeta(D)-IRES-GFP (RDB16741) , pcDNA3-FLAG-mouse IkB-zeta(D) (RDB16742) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
Human and Animal Cells MCF7(RCB1904) The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity.
Human and Animal Cells LM8(RCB1450) Onionin A, a sulfur-containing compound isolated from onions, impairs tumor development and lung metastasis by inhibiting the protumoral and immunosuppressive functions of myeloid cells.
DNA material pCAmGCSF (RDB01522) , pCAZ 2 (RDB01870). PM01183 inhibits myeloid-derived suppressor cells in vitro and in vivo.