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  • Search Condition : Filter (MeSH = Signal Transduction / immunology)
Species Resource
Pathogenic microorganisms ? Interaction of CagA with Crk plays an important role in Helicobacter pylori-induced loss of gastric epithelial cell adhesion.
DNA material pIL-2R gamma 2 (RDB01201) Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera.
Mice Endoplasmic reticulum stress regulator XBP-1 contributes to effector CD8+ T cell differentiation during acute infection.
C.elegans tm1907 , tm1053 Pseudomonas aeruginosa suppresses host immunity by activating the DAF-2 insulin-like signaling pathway in Caenorhabditis elegans.
C.elegans tm331 Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity.
Mice IRF-3 Knockout mice , C57BL/6J Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process.
Mice EpoR(-/-) ::HG1-EpoR mouse Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-κB-inducible immune pathways.
Mice IRF-3遺伝子欠損マウス Multiple preconditioning paradigms converge on interferon regulatory factor-dependent signaling to promote tolerance to ischemic brain injury.
General Microbes JCM 2012 Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages.
Drosophila 7717R-1 , 7717R-2 The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila.
Drosophila 8293R-1 , 8293R-2 Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway.
General Microbes JCM 7041 A TLR2 ligand suppresses allergic inflammatory reactions by acting directly on mast cells.
Drosophila The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila.
Drosophila PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan.
General Microbes JCM 1542 Efficient capture of Candida albicans and zymosan by SIGNR1 augments TLR2-dependent TNF-α production.
Drosophila An immune-responsive Serpin regulates the melanization cascade in Drosophila.
Drosophila Drosophila immunity: analysis of PGRP-SB1 expression, enzymatic activity and function.
Drosophila DGRC#109029 Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.
DNA material pMY-FLAG-mouse IkB-zeta(D)-IRES-GFP (RDB16741) , pcDNA3-FLAG-mouse IkB-zeta(D) (RDB16742) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
DNA material pGL4-IL-9 promoter reporter (positions -464 to +284) (RDB16735) The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.