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  • Search Condition : Filter (MeSH = Signal Transduction / immunology)
Species Resource Title
Human and Animal Cells 40LB(RCB5304) PI3Kγ in B cells promotes antibody responses and generation of antibody-secreting cells.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) NFκB and TGFβ contribute to the expression of PTPN3 in activated human lymphocytes.
Human and Animal Cells Meth-A(RCB0464) Overexpression of CD82 on human T cells enhances LFA-1 / ICAM-1-mediated cell-cell adhesion: functional association between CD82 and LFA-1 in T cell activation.
Human and Animal Cells OP9(RCB1124) A dual role for talin in NK cell cytotoxicity: activation of LFA-1-mediated cell adhesion and polarization of NK cells.
C.elegans tm1406 , tm1165 GABAergic synapses suppress intestinal innate immunity via insulin signaling in Caenorhabditis elegans.
C.elegans tm4919 Activation of mitochondrial unfolded protein response protects against multiple exogenous stressors.
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , Ca9-22(RCB1976) PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
Human and Animal Cells JHOS-2(RCB1521) Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells.
DNA material , Human and Animal Cells CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393) , HeLa , A549(RCB0098) , HCT116(RCB2979) , MKN45(RCB1001) , PC-3(RCB2145) , K562(RCB1897) , B16F1(RCB2649) , B16F10(RCB2630) , ... Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.
Human and Animal Cells RAW 264(RCB0535) Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species.
Human and Animal Cells Jurkat(RCB0806) Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A.
Human and Animal Cells OV2944-HM-1(RCB1483) Tumour-associated neutrophils orchestrate intratumoural IL-8-driven immune evasion through Jagged2 activation in ovarian cancer.
Human and Animal Cells LM8(RCB1450) Activation of TLR4 signaling inhibits progression of osteosarcoma by stimulating CD8-positive cytotoxic lymphocytes.
Mice RBRC04395 Breast cancer cells promote CD169+ macrophage-associated immunosuppression through JAK2-mediated PD-L1 upregulation on macrophages.
Drosophila 11992R-1 , 11992R-2 , 6084R-1 , 6084R-3 Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila.
Drosophila DGRC#109029 Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.
DNA material pGL4-IL-9 promoter reporter (positions -464 to +284) (RDB16735) The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
DNA material pMY-FLAG-mouse IkB-zeta(D)-IRES-GFP (RDB16741) , pcDNA3-FLAG-mouse IkB-zeta(D) (RDB16742) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.