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  • Search Condition : Filter (MeSH = Signal Transduction / immunology)
Species Resource
Drosophila 7717R-1 , 7717R-2 The MAPKKK Mekk1 regulates the expression of Turandot stress genes in response to septic injury in Drosophila.
Drosophila 8293R-1 , 8293R-2 Inhibitor of apoptosis 2 and TAK1-binding protein are components of the Drosophila Imd pathway.
General Microbes JCM 7041 A TLR2 ligand suppresses allergic inflammatory reactions by acting directly on mast cells.
Drosophila The RING-finger scaffold protein Plenty of SH3s targets TAK1 to control immunity signalling in Drosophila.
Drosophila PGRP-LC and PGRP-LE have essential yet distinct functions in the drosophila immune response to monomeric DAP-type peptidoglycan.
Mice IRF-3 Knockout mice , C57BL/6J Critical role of the IFN-stimulated gene factor 3 complex in TLR-mediated IL-27p28 gene expression revealing a two-step activation process.
Mice EpoR(-/-) ::HG1-EpoR mouse Erythropoietin contrastingly affects bacterial infection and experimental colitis by inhibiting nuclear factor-κB-inducible immune pathways.
Human and Animal Cells 293T(RCB2202) Endoplasmic Protein Nogo-B (RTN4-B) Interacts with GRAMD4 and Regulates TLR9-Mediated Innate Immune Responses.
Human and Animal Cells PD-1/PD-L blockade prevents anergy induction and enhances the anti-tumor activities of glycolipid-activated invariant NKT cells.
Mice B6-Tg(CAG-FLPe)36(RBRC01834) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
Human and Animal Cells MRC-5(RCB0211) , known PDL(RCB0218) ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses.
DNA material pMY-FLAG-mouse IkB-zeta(D)-IRES-GFP (RDB16741) , pcDNA3-FLAG-mouse IkB-zeta(D) (RDB16742) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
DNA material pGL4-IL-9 promoter reporter (positions -464 to +284) (RDB16735) The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
Human and Animal Cells Salmonella administration induces a reduction of wheel-running activity via a TLR5-, but not a TLR4, dependent pathway in mice.
Human and Animal Cells Possible Involvement of Sphingosine-1-Phosphate/G(i)/RhoA pathways in adherence of eosinophils to pulmonary endothelium.
Human and Animal Cells Decreased mitochondrial apoptotic priming underlies stroma-mediated treatment resistance in chronic lymphocytic leukemia.
General Microbes JCM 2012 Bacterial teichoic acids reverse predominant IL-12 production induced by certain lactobacillus strains into predominant IL-10 production via TLR2-dependent ERK activation in macrophages.
Human and Animal Cells SKN (RCB0513) The mutation in the ATP-binding region of JAK1, identified in human uterine leiomyosarcomas, results in defective interferon-gamma inducibility of TAP1 and LMP2.
Human and Animal Cells MH7A (RCB1512) A pro-inflammatory role for A20 and ABIN family proteins in human fibroblast-like synoviocytes in rheumatoid arthritis.
Human and Animal Cells RAW 264 (RCB0535) Retinoblastoma protein-interacting zinc finger 1 (RIZ1) participates in RANKL-induced osteoclast formation via regulation of NFATc1 expression.