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  • 61 Hits
  • Search Condition : Filter (MeSH = Signal Transduction / immunology)
Species Resource Title
Human and Animal Cells HSC-2(RCB1945) , HSC-3(RCB1975) , Ca9-22(RCB1976) PLOD2-driven IL-6/STAT3 signaling promotes the invasion and metastasis of oral squamous cell carcinoma via activation of integrin β1.
Human and Animal Cells JHOS-2(RCB1521) Immunosuppression through constitutively activated NF-κB signalling in human ovarian cancer and its reversal by an NF-κB inhibitor.
Human and Animal Cells Atg5^(+/+)MEF(RCB2710) , Atg5^(-/-)MEF(RCB2711) Viral mediated redirection of NEMO/IKKγ to autophagosomes curtails the inflammatory cascade.
DNA material CSII-CMV-MCS-IRES2-Bsd (RDB04385) RIG-I triggers a signaling-abortive anti-SARS-CoV-2 defense in human lung cells.
DNA material , Human and Animal Cells CSII-EF-MCS-IRES2-Venus (RDB04384) , pCMV-VSV-G-RSV-Rev (RDB04393) , HeLa , A549 , HCT116 , MKN45 , PC-3 , K562 Recognition of tumor cells by Dectin-1 orchestrates innate immune cells for anti-tumor responses.
Human and Animal Cells RAW 264(RCB0535) Urolithin A attenuates pro-inflammatory mediator production by suppressing PI3-K/Akt/NF-κB and JNK/AP-1 signaling pathways in lipopolysaccharide-stimulated RAW264 macrophages: Possible involvement of NADPH oxidase-derived reactive oxygen species.
Human and Animal Cells Jurkat(RCB0806) Raft-dependent endocytic movement and intracellular cluster formation during T cell activation triggered by concanavalin A.
Human and Animal Cells OV2944-HM-1(RCB1483) Tumour-associated neutrophils orchestrate intratumoural IL-8-driven immune evasion through Jagged2 activation in ovarian cancer.
Human and Animal Cells LM8(RCB1450) Activation of TLR4 signaling inhibits progression of osteosarcoma by stimulating CD8-positive cytotoxic lymphocytes.
Mice RBRC04395 Breast cancer cells promote CD169+ macrophage-associated immunosuppression through JAK2-mediated PD-L1 upregulation on macrophages.
Drosophila 11992R-1 , 11992R-2 , 6084R-1 , 6084R-3 Sugar Alcohols of Polyol Pathway Serve as Alarmins to Mediate Local-Systemic Innate Immune Communication in Drosophila.
Drosophila DGRC#109029 Cell-Specific Imd-NF-κB Responses Enable Simultaneous Antibacterial Immunity and Intestinal Epithelial Cell Shedding upon Bacterial Infection.
DNA material pGL4-IL-9 promoter reporter (positions -464 to +284) (RDB16735) The DNA-binding inhibitor Id3 regulates IL-9 production in CD4(+) T cells.
DNA material pMY-FLAG-mouse IkB-zeta(D)-IRES-GFP (RDB16741) , pcDNA3-FLAG-mouse IkB-zeta(D) (RDB16742) Enhanced apoptosis by disruption of the STAT3-IκB-ζ signaling pathway in epithelial cells induces Sjögren's syndrome-like autoimmune disease.
Human and Animal Cells MRC-5(RCB0211) , known PDL(RCB0218) ZAPS is a potent stimulator of signaling mediated by the RNA helicase RIG-I during antiviral responses.
Drosophila 5680R-1 , 5680R-2 JNK/FOXO mediated PeroxiredoxinV expression regulates redox homeostasis during Drosophila melanogaster gut infection.
Mice RBRC00850 TLR7 mediated viral recognition results in focal type I interferon secretion by dendritic cells.
General Microbes JCM 8714 , JCM 8727 , JCM 1132 , JCM 1134 , JCM 5344 , JCM 1149 Nucleic acids of Enterococcus faecalis strain EC-12 are potent Toll-like receptor 7 and 9 ligands inducing interleukin-12 production from murine splenocytes and murine macrophage cell line J774.1.
Pathogenic microorganisms ? Dectin-1 and Dectin-2 in innate immunity against fungi.
C.elegans tm5176 , tm1968 An evolutionarily conserved innate immunity protein interaction network.