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論文 - 一覧

  • 14 Hits
  • 検索条件 : 絞込み (MeSH = Small Molecule Libraries / pharmacology)
生物種 リソース名 タイトル
線虫 tm985 Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
ヒト・動物細胞 MIA Paca2(RCB2094) , LU65(RCB1967) Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models.
ヒト・動物細胞 HeLa(RCB0007) Small molecule targeting r(UGGAA)n disrupts RNA foci and alleviates disease phenotype in Drosophila model.
ヒト・動物細胞 EBC-1(RCB1965) PARP7 negatively regulates the type I interferon response in cancer cells and its inhibition triggers antitumor immunity.
ヒト・動物細胞 A549 , MKN74(RCB1002) , PANC-1(RCB2095) , MIA Paca2(RCB2094) Identification of a Small Molecule That Enhances Ferroptosis via Inhibition of Ferroptosis Suppressor Protein 1 (FSP1).
ヒト・動物細胞 OS-RC-2(RCB0735) , TUHR10TKB(RCB1275) , TUHR14TKB(RCB1383) Oncogenic roles of TOPK and MELK, and effective growth suppression by small molecular inhibitors in kidney cancer cells.
線虫 tm611 Proteinase K is an activator for the male-dependent spermiogenesis pathway in Caenorhabditis elegans: Its application to pharmacological dissection of spermiogenesis.
ヒト・動物細胞 TE-4(RCB2097) Small molecule inhibitors and CRISPR/Cas9 mutagenesis demonstrate that SMYD2 and SMYD3 activity are dispensable for autonomous cancer cell proliferation.
線虫 tm1325 Chemical activation of a food deprivation signal extends lifespan.
ヒト・動物細胞 HCT116(RCB2979) H3B-8800, an orally available small-molecule splicing modulator, induces lethality in spliceosome-mutant cancers.
線虫 tm1689 Rescue of ATXN3 neuronal toxicity in Caenorhabditiselegans by chemical modification of endoplasmic reticulum stress.
線虫 tm4067 Stimulation of host immune defenses by a small molecule protects C. elegans from bacterial infection.
シロイヌナズナ / 植物培養細胞・遺伝子 rpc00008 Novel Abscisic Acid Antagonists Identified with Chemical Array Screening.
遺伝子材料 pCAG-HIVgp (RDB04394) , pCMV-VSV-G (RDB04392). Rapid, efficient, and simple motor neuron differentiation from human pluripotent stem cells.