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  • 検索条件 : 絞込み (MeSH = Sphingolipids / metabolism)
生物種 リソース名 タイトル
遺伝子材料 pCDNA3-DEGS1 (RDB20900) , pCDNA3-DEGS2 (RDB20901) , pCDNA3-HygR (RDB20899) Loss of function and reduced levels of sphingolipid desaturase DEGS1 variants are both relevant in disease mechanism.
ヒト・動物細胞 CHO-K1(RCB0285) , LY-B(RCB1698) , LY-B/cLCB1(RCB1699) Specialized contact sites regulate the fusion of chlamydial inclusion membranes.
線虫 tm1547 Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans.
線虫 tm985 Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
ヒト・動物細胞 293T(RCB2202) Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
酵母 Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.
線虫 RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic acid-based metabolites such as lipids.
ショウジョウバエ CAS‐0003 Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo.
ショウジョウバエ A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing.
線虫 tm1011 Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships.
ヒト・動物細胞 MRC-5 Development of a new inhibitor of glucosylceramide synthase.
ヒト・動物細胞 Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.
遺伝子材料 pDEST/mCherry-D4 (RDB18944) , pET28/His6-EGFP-D4 (RDB13961) , pDEST/mCherry-PLCD1-PH (RDB16764) , pDEST/mCherry-PIP5KB (RDB16765) , pDEST/mCherry-Tubby C (RDB16766) , pDEST/mCherry-CeRhoA (RDB16767) , pDEST/mCherry-NT-Lys (RDB18943) A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4,5-bisphosphate to the cleavage furrow during cytokinesis.
実験動物マウス RBRC00398 Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway.
遺伝子材料 , ヒト・動物細胞 pGCDNsam-Fam57b_var1-IRES-EGFP(IG) (RDB12135) , pGCDNsam-Fam57b_var1FLAG-IG (RDB12136) , pGCDNsam-Fam57b_var2-IG (RDB12137) , pGCDNsam-Fam57b_var2FLAG-IG (RDB12138) , pGCDNsam-Fam57b_var3-IG (RDB12139) , pGCDNsam-Fam57b_var3FLAG-IG (RDB12140) , ST2(RCB0224) Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis.
細胞性粘菌 Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs.
ショウジョウバエ 30502R-1 , 30502R-4 Survival strategies of a sterol auxotroph.
シロイヌナズナ / 植物培養細胞・遺伝子 pda09352 , pda09604 , pda04689 , pda04178 , pda02078 Degradation of long-chain base 1-phosphate (LCBP) in Arabidopsis: functional characterization of LCBP phosphatase involved in the dehydration stress response.