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  • Search Condition : Filter (MeSH = Sphingolipids / metabolism)
Species Resource Title
Human and Animal Cells CHO-K1(RCB0285) , LY-B(RCB1698) , LY-B/cLCB1(RCB1699) Specialized contact sites regulate the fusion of chlamydial inclusion membranes.
C.elegans tm1547 Transcriptional suppression of sphingolipid catabolism controls pathogen resistance in C. elegans.
C.elegans tm985 Chemical and genetic rescue of in vivo progranulin-deficient lysosomal and autophagic defects.
Human and Animal Cells 293T(RCB2202) Impact of Gba2 on neuronopathic Gaucher's disease and α-synuclein accumulation in medaka (Oryzias latipes).
Yeast Sphingolipid/Pkh1/2-TORC1/Sch9 Signaling Regulates Ribosome Biogenesis in Tunicamycin-Induced Stress Response in Yeast.
C.elegans RNAi-based biosynthetic pathway screens to identify in vivo functions of non-nucleic acid-based metabolites such as lipids.
Drosophila CAS‐0003 Lipophagy prevents activity-dependent neurodegeneration due to dihydroceramide accumulation in vivo.
Drosophila A Drosophila Genome-Wide Screen Identifies Regulators of Steroid Hormone Production and Developmental Timing.
C.elegans tm1011 Coordinate regulation of lipid metabolism by novel nuclear receptor partnerships.
Human and Animal Cells Development of a new inhibitor of glucosylceramide synthase.
Human and Animal Cells Cell polarity factor Par3 binds SPTLC1 and modulates monocyte serine palmitoyltransferase activity and chemotaxis.
DNA material pET28/His6-EGFP-D4 (RDB13961) , pDEST/mCherry-PLCD1-PH (RDB16764) , pDEST/mCherry-PIP5KB (RDB16765) , pDEST/mCherry-Tubby C (RDB16766) , pDEST/mCherry-CeRhoA (RDB16767) , pDEST/mCherry-NT-Lys (RDB18943) , pDEST/mCherry-D4 (RDB18944) A role for sphingomyelin-rich lipid domains in the accumulation of phosphatidylinositol-4,5-bisphosphate to the cleavage furrow during cytokinesis.
Mice RBRC00398 Annexin II-dependent actin remodelling evoked by hydrogen peroxide requires the metalloproteinase/sphingolipid pathway.
DNA material , Human and Animal Cells pGCDNsam-Fam57b_var1-IRES-EGFP(IG) (RDB12135) , pGCDNsam-Fam57b_var1FLAG-IG (RDB12136) , pGCDNsam-Fam57b_var2-IG (RDB12137) , pGCDNsam-Fam57b_var2FLAG-IG (RDB12138) , pGCDNsam-Fam57b_var3-IG (RDB12139) , pGCDNsam-Fam57b_var3FLAG-IG (RDB12140) , ST2(RCB0224) Fam57b (family with sequence similarity 57, member B), a novel peroxisome proliferator-activated receptor γ target gene that regulates adipogenesis through ceramide synthesis.
Cellular slime molds Overexpression of sphingosine-1-phosphate lyase or inhibition of sphingosine kinase in Dictyostelium discoideum results in a selective increase in sensitivity to platinum-based chemotherapy drugs.
Drosophila 30502R-1 , 30502R-4 Survival strategies of a sterol auxotroph.
Arabidopsis / Cultured plant cells, genes pda09352 , pda09604 , pda04689 , pda04178 , pda02078 Degradation of long-chain base 1-phosphate (LCBP) in Arabidopsis: functional characterization of LCBP phosphatase involved in the dehydration stress response.