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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / genetics*)
Species Resource
DNA material pCALwL (RDB01679) , AxCALNLNZ (RDB01750). Targeting the replication of adenovirus to p53-defective thyroid carcinoma with a p53-regulated Cre/loxP system.
C.elegans tm853 C. elegans SIR-2.1 translocation is linked to a proapoptotic pathway parallel to cep-1/p53 during DNA damage-induced apoptosis.
Medaka MT893 , MT894 p53 Mutation suppresses adult neurogenesis in medaka fish (Oryzias latipes).
C.elegans The tumour suppressor CYLD regulates the p53 DNA damage response.
DNA material pFLAG-CMV-5a-RPL5 (RDB17329) , pFLAG-CMV-5a-RPL11 (RDB17330) GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
Drosophila p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.
Drosophila 11859R-2 , 3608R-1 , 1954R-1 , 2829R-1 , 32134R-2 p53- and ERK7-dependent ribosome surveillance response regulates Drosophila insulin-like peptide secretion.
DNA material AxCANCre (RDB01748) , AxCALNLNZ (RDB01750). An in vitro system to characterize prostate cancer progression identified signaling required for self-renewal.
Mice C57BL-p53+/-(RBRC01361) N-Methyl, N-propynyl-2-phenylethylamine (MPPE), a Selegiline Analog, Attenuates MPTP-induced Dopaminergic Toxicity with Guaranteed Behavioral Safety: Involvement of Inhibitions of Mitochondrial Oxidative Burdens and p53 Gene-elicited Pro-apoptotic Change.
Mice B6.Cg-Trp53<tm1Sia>/Rbrc(RBRC01361) The Transcriptional Landscape of p53 Signalling Pathway.
Mice B6.129S-Atg5<tm1Myok>(RBRC02975) p53 status determines the role of autophagy in pancreatic tumour development.
Human and Animal Cells 293T(RCB2202) Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.
Human and Animal Cells Nuclear factor-kappaB sensitizes to benzyl isothiocyanate-induced antiproliferation in p53-deficient colorectal cancer cells.
Human and Animal Cells Exclusive Association of p53 Mutation with Super-High Methylation of Tumor Suppressor Genes in the p53 Pathway in a Unique Gastric Cancer Phenotype.
Human and Animal Cells HHUA(RCB0658) Lipocalin 2 Enhances Migration and Resistance against Cisplatin in Endometrial Carcinoma Cells.
Human and Animal Cells Induction of nuclear translocation of mutant cytoplasmic p53 by geranylgeranoic acid in a human hepatoma cell line.
Human and Animal Cells 293 (RCB1637) A single recombinant adenovirus expressing p53 and p21-targeting artificial microRNAs efficiently induces apoptosis in human cancer cells.
DNA material , Human and Animal Cells pGL4-phTP53AIP1 (RDB07410) , MH7A (RCB1512) Anti-apoptotic roles for the mutant p53R248Q through suppression of p53-regulated apoptosis-inducing protein 1 in the RA-derived fibroblast-like synoviocyte cell line MH7A.
Human and Animal Cells 293(RCB1637) DNA damage-responsive transgene expression mediated by the p53 promoter with transcriptional amplification.
Human and Animal Cells Mutant p53 gain-of-function induces epithelial-mesenchymal transition through modulation of the miR-130b-ZEB1 axis.