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  • Search Condition : Filter (MeSH = Tumor Suppressor Protein p53 / genetics*)
Species Resource Title
Human and Animal Cells 293(RCB1637) A DDX31/Mutant-p53/EGFR Axis Promotes Multistep Progression of Muscle-Invasive Bladder Cancer.
Human and Animal Cells NB9(RCB0447) , NB16(RCB0478) , NB69(RCB0480) p21 (WAF1/Cip1/Sdi1/Pic1) mRNA is expressed in neuroblastoma cell lines but not in Ewing's sarcoma and primitive neuroectodermal tumor cell lines.
Human and Animal Cells A549 Characterization of miR-34a-Induced Epithelial-Mesenchymal Transition in Non-Small Lung Cancer Cells Focusing on p53.
Human and Animal Cells KGN(RCB1154) FOXL2 and FOXA1 cooperatively assemble on the TP53 promoter in alternative dimer configurations.
Drosophila DGRC#204829 Chk2-p53 and JNK in irradiation-induced cell death of hematopoietic progenitors and differentiated cells in Drosophila larval lymph gland.
Zebrafish Tg(krt4p:gal4; UAS:EGFP) Zebrafish imaging reveals TP53 mutation switching oncogene-induced senescence from suppressor to driver in primary tumorigenesis.
Human and Animal Cells TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) APR-246 induces apoptosis and enhances chemo-sensitivity via activation of ROS and TAp73-Noxa signal in oesophageal squamous cell cancer with TP53 missense mutation.
Human and Animal Cells HuH-6(RCB1367) A MYC-aurora kinase A protein complex represents an actionable drug target in p53-altered liver cancer.
Human and Animal Cells HHUA(RCB0658) An upstream estrogen response element linked to exogenous p53 tumor suppressor gene expression differentiates effects of the codon 72 polymorphism.
Human and Animal Cells JHOC-5(RCB1520) , JHOC-9(RCB2226) High Expression of p21 as a Potential Therapeutic Target in Ovarian Clear-cell Carcinoma.
Human and Animal Cells Saos-2(RCB0428) Inhibition of mutant p53 phosphorylation at serine 15 or serine 315 partially restores the function of wild-type p53.
Human and Animal Cells JHOC-7(RCB1688) , JHOC-9(RCB2226) MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
Human and Animal Cells EEB(RCB2345) TP53 deficiency permits chromosome abnormalities and karyotype heterogeneity in acute myeloid leukemia.
Drosophila p53-dependent programmed necrosis controls germ cell homeostasis during spermatogenesis.
DNA material pFLAG-CMV-5a-RPL5 (RDB17329) , pFLAG-CMV-5a-RPL11 (RDB17330) GRWD1 negatively regulates p53 via the RPL11-MDM2 pathway and promotes tumorigenesis.
Mice RBRC01361 Opposing effects of acute versus chronic inhibition of p53 on decitabine's efficacy in myeloid neoplasms.
Human and Animal Cells HuCCT1(RCB1960) , RBE(RCB1292) Genomic perturbations reveal distinct regulatory networks in intrahepatic cholangiocarcinoma.
Human and Animal Cells TE-1(RCB1894) , TE-4(RCB2097) , TE-5(RCB1949) , TE-6(RCB1950) , TE-8(RCB2098) , TE-9(RCB1988) , TE-10(RCB2099) , TE-11(RCB2100) , TE-14(RCB2101) PRIMA-1 induces p53-mediated apoptosis by upregulating Noxa in esophageal squamous cell carcinoma with TP53 missense mutation.
C.elegans tm3768 The tumour suppressor CYLD regulates the p53 DNA damage response.
Human and Animal Cells 293T(RCB2202) Regulation of tubular recycling endosome biogenesis by the p53-MICALL1 pathway.