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  • Search Condition : Filter (MeSH = Anaphase-Promoting Complex-Cyclosome)
Species Resource
C.elegans tm1664 The C. elegans anaphase promoting complex and MBK-2/DYRK kinase act redundantly with CUL-3/MEL-26 ubiquitin ligase to degrade MEI-1 microtubule-severing activity after meiosis.
Yeast FY13046 , FY9987(GT260) Spindle checkpoint activation at meiosis I advances anaphase II onset via meiosis-specific APC/C regulation.
Yeast BY22828 The ubiquitin-conjugating enzymes, Ubc4 and Cdc34, mediate cadmium resistance in budding yeast through different mechanisms.
Yeast cDNA library The transcription factor Atf1 binds and activates the APC/C ubiquitin ligase in fission yeast.
Yeast genomic DNA library A brute force postgenome approach to identify temperature-sensitive mutations that negatively interact with separase and securin plasmids.
Yeast cDNA library The APC/C subunit Cdc16/Cut9 is a contiguous tetratricopeptide repeat superhelix with a homo-dimer interface similar to Cdc27.
Yeast cDNA library (pTN-TH7) Structure of the mitotic checkpoint complex.
C.elegans tm936 , tm1021 emb-1 encodes the APC16 subunit of the Caenorhabditis elegans anaphase-promoting complex.
Zebrafish RIKEN WT , SAGFF(LF)168A The ubiquitin proteasome system is required for cell proliferation of the lens epithelium and for differentiation of lens fiber cells in zebrafish.
Arabidopsis / Cultured plant cells, genes pst15307 GIGAS CELL1, a novel negative regulator of the anaphase-promoting complex/cyclosome, is required for proper mitotic progression and cell fate determination in Arabidopsis.
Drosophila 6759R-3 , 10800R-1 , 10800R-2 The anaphase-promoting complex/cyclosome (APC/C) is required for rereplication control in endoreplication cycles.
Human and Animal Cells 293T (RCB2202) The anaphase-promoting complex/cyclosome activator Cdh1 modulates Rho GTPase by targeting p190 RhoGAP for degradation.