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  • Search Condition : Filter (MeSH = Cell Cycle Checkpoints / genetics)
Species Resource Title
Yeast FY13012 , FY9954 A point mutation in the FAT domain constitutively increases the kinase activity of Rad3ATR and bypasses the requirement for 9-1-1 phosphorylation to activate the DNA replication checkpoint.
Mice RBRC01361 , RBRC00213 p53 suppresses tetraploid development in mice.
Drosophila DGRC#108356 Cell Cycle Regulation by NF-YC in Drosophila Eye Imaginal Disc: Implications for Synchronization in the Non-Proliferative Region.
Human and Animal Cells HSC-4(RCB1902) , HO-1-u-1(RCB2102) , SAS(RCB1974) , Sa3(RCB0980) , Ca9-22(RCB1976) , HSC-3(RCB1975) , HSC-2(RCB1945) Critical role of deoxynucleotidyl transferase terminal interacting protein 1 in oral cancer.
Mice RBRC01151 , RBRC02707 Cell cycle arrest determines adult neural stem cell ontogeny by an embryonic Notch-nonoscillatory Hey1 module.
Human and Animal Cells RAW 264(RCB0535) , THP-1(RCB1189) Downregulation of rRNA transcription triggers cell differentiation.
Human and Animal Cells GCIY(RCB0555) , OVK18(RCB1903) WRN helicase is a synthetic lethal target in microsatellite unstable cancers.
Human and Animal Cells HL60 , KG-1a(RCB1928) , NALM-6(RCB1933) , MOLT-4(RCB0206) , SKW-3(RCB1168) High expression of PSF1 promotes drug resistance and cell cycle transit in leukemia cells.
Human and Animal Cells 293T(RCB2202) GPRC5A facilitates cell proliferation through cell cycle regulation and correlates with bone metastasis in prostate cancer.
Human and Animal Cells Huh-7 Rpn10 promotes tumor progression by regulating hypoxia-inducible factor 1 alpha through the PTEN/Akt signaling pathway in hepatocellular carcinoma.
Human and Animal Cells ATDC5(RCB0565) FOXO1 transcription factor regulates chondrogenic differentiation through transforming growth factor β1 signaling.
Human and Animal Cells G-415(RCB2640) Overexpression of SNORA21 suppresses tumorgenesis of gallbladder cancer in vitro and in vivo.
Drosophila Drosophila Histone Demethylase KDM4A Has Enzymatic and Non-enzymatic Roles in Controlling Heterochromatin Integrity.
Drosophila DGRC#111872 JNK-dependent cell cycle stalling in G2 promotes survival and senescence-like phenotypes in tissue stress.
Yeast FY20405 , FY20348 , FY21303 , FY21304 , FY20867 , FY8496 , FY8495 , FY8734 , FY8450 , FY20045 , ... Regulation of transcriptional silencing and chromodomain protein localization at centromeric heterochromatin by histone H3 tyrosine 41 phosphorylation in fission yeast.
DNA material pKM2L-phP21 (RDB05893) ASPL-TFE3 Oncoprotein Regulates Cell Cycle Progression and Induces Cellular Senescence by Up-Regulating p21.
Pathogenic microorganisms IFM 49144 The CRZ1/SP1-like gene links survival under limited aeration, cell integrity and biofilm formation in the pathogenic yeast Cryptococcus neoformans.
C.elegans tm4374 , tm1842 , tm853 Base excision repair AP endonucleases and mismatch repair act together to induce checkpoint-mediated autophagy.
C.elegans tm1145 The 53BP1 homolog in C. elegans influences DNA repair and promotes apoptosis in response to ionizing radiation.
Human and Animal Cells HO-1-u-1(RCB2102) , HSC-4(RCB1902) , HSC-2(RCB1945) , HSC-3(RCB1975) , Sa3(RCB0980) , Ca9-22(RCB1976) , SAS(RCB1974) Semaphorin7A Promotion of Tumoral Growth and Metastasis in Human Oral Cancer by Regulation of G1 Cell Cycle and Matrix Metalloproteases: Possible Contribution to Tumoral Angiogenesis.