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  • Search Condition : Filter (MeSH = DNA Breaks, Double-Stranded*)
Species Resource
C.elegans tm750 Targeted engineering of the Caenorhabditis elegans genome following Mos1-triggered chromosomal breaks.
C.elegans tm1145 BRC-1 acts in the inter-sister pathway of meiotic double-strand break repair.
C.elegans tm1086 HTP-3 links DSB formation with homolog pairing and crossing over during C. elegans meiosis.
C.elegans tm2334 Loading of meiotic cohesin by SCC-2 is required for early processing of DSBs and for the DNA damage checkpoint.
C.elegans tm2940 , tm1579 , tm853 , tm1670 , tm899 The Caenorhabditis elegans homolog of Gen1/Yen1 resolvases links DNA damage signaling to DNA double-strand break repair.
DNA material CSII-EF-MCS-IRES-hrGFP (RDB04382) , CSII-CMV-MCS (RDB04377) DNA double strand break repair enzymes function at multiple steps in retroviral infection.
DNA material S. pombe YFP-FLAG-His , SpYFH06D01 (SPW082473) , SpYFH25C07 (SPW090055). A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks.
C.elegans E4 ligase-specific ubiquitination hubs coordinate DNA double-strand-break repair and apoptosis.
C.elegans Interdependent and separable functions of Caenorhabditis elegans MRN-C complex members couple formation and repair of meiotic DSBs.
Drosophila The balancer chromosomes were CyO and TM3 (Kyoto Stock Center). The double-stranded break-forming activity of plant SPO11s and a novel rice SPO11 revealed by a Drosophila bioassay.
C.elegans tm1842 The Caenorhabditis elegans WRN helicase promotes double-strand DNA break repair by mediating end resection and checkpoint activation.
C.elegans tm2176 New Insights into the Post-Translational Regulation of DNA Damage Response and Double-Strand Break Repair in Caenorhabditis elegans.
C.elegans tm2572 , tm2606 , tm2026 , tm1145 A Polymerase Theta-dependent repair pathway suppresses extensive genomic instability at endogenous G4 DNA sites.
C.elegans tm2026 Polymerase theta-mediated end joining of replication-associated DNA breaks in C. elegans.
C.elegans tm3298 The C. elegans DSB-2 protein reveals a regulatory network that controls competence for meiotic DSB formation and promotes crossover assurance.
DNA material AxCANCre (RDB01748) The CDKN1B-RB1-E2F1 pathway protects mouse spermatogonial stem cells from genomic damage.
C.elegans tm1458 Meiotic double-strand breaks uncover and protect against mitotic errors in the C. elegans germline.
C.elegans tm574 , tm1813 , tm583 Meiotic errors activate checkpoints that improve gamete quality without triggering apoptosis in male germ cells.
C.elegans tm2134 , tm1866 , tm1086 , tm1268 Overlapping mechanisms promote postsynaptic RAD-51 filament disassembly during meiotic double-strand break repair.
Arabidopsis / Cultured plant cells, genes rpc00008 Arabidopsis replication protein A 70a is required for DNA damage response and telomere length homeostasis.