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  • Search Condition : Filter (MeSH = DNA Breaks, Double-Stranded*)
Species Resource Title
Human and Animal Cells HeLa/Fucci(RCB2812) The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells.
Mice RBRC00886 Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis.
Human and Animal Cells HCT116(RCB2979) Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
Human and Animal Cells HeLa.S3 Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4.
Human and Animal Cells V79(RCB0008) DNA-double strand breaks enhance the expression of major histocompatibility complex class II through the ATM-NF-κΒ-IRF1-CIITA pathway.
Human and Animal Cells HFL-III(RCB0523) The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function.
C.elegans Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1-BARD1 in Caenorhabditis elegans.
Human and Animal Cells A549 Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair.
Human and Animal Cells A549(RCB0098) RNF8 promotes high linear energy transfer carbon-ion-induced DNA double-stranded break repair in serum-starved human cells.
Human and Animal Cells A549(RCB0098) Multi-walled carbon nanotube induces nitrative DNA damage in human lung epithelial cells via HMGB1-RAGE interaction and Toll-like receptor 9 activation.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) Mitotic cells can repair DNA double-strand breaks via a homology-directed pathway.
Human and Animal Cells KGN(RCB1154) FOXL2 directs DNA double-strand break repair pathways by differentially interacting with Ku.
Human and Animal Cells NB1RGB(RCB0222) , 201B7(HPS0063) DNA Damage Response After Ionizing Radiation Exposure in Skin Keratinocytes Derived from Human-Induced Pluripotent Stem Cells.
C.elegans tm1298 , tm1145 , tm3081 In vivo analysis of FANCD2 recruitment at meiotic DNA breaks in Caenorhabditis elegans.
C.elegans tm1842 , tm2572 Hypersensitivity to DNA double-strand breaks associated with PARG deficiency is suppressed by exo-1 and polq-1 mutations in Caenorhabditis elegans.
C.elegans tm1524 , tm2026 , tm2027 , tm1842 , tm1086 , tm2134 Meiotic Double-Strand Break Proteins Influence Repair Pathway Utilization.
Human and Animal Cells B16/BL6(RCB2638) DNA Strand Break Properties of Protoporphyrin IX by X-Ray Irradiation against Melanoma.
Human and Animal Cells 409B2(HPS0076) Simultaneous precise editing of multiple genes in human cells.
C.elegans tm1842 , tm1524 Interdependent and separable functions of Caenorhabditis elegans MRN-C complex members couple formation and repair of meiotic DSBs.
Human and Animal Cells L5178Y(RCB0135) , M10(RCB0136) In cellulo phosphorylation of DNA double-strand break repair protein XRCC4 on Ser260 by DNA-PK.