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  • Search Condition : Filter (MeSH = DNA Breaks, Double-Stranded*)
Species Resource Title
DNA material tFucci(CA)2/pCSII-EF (RDB15446) Homologous recombination promotes non-immunogenic mitotic cell death upon DNA damage.
Mice RBRC02975 Increased DNA damage in full-grown oocytes is correlated with diminished autophagy activation.
Human and Animal Cells A549(RCB0098) , HeLa Discovery of novel DNA-damaging agents through phenotypic screening for DNA double-strand break.
C.elegans ATM/ATR kinases link the synaptonemal complex and DNA double-strand break repair pathway choice.
C.elegans tm1670 , tm2842 , tm1524 , tm2026 R-loop-induced irreparable DNA damage evades checkpoint detection in the C. elegans germline.
C.elegans tm2134 , tm2026 Helicase Q promotes homology-driven DNA double-strand break repair and prevents tandem duplications.
C.elegans tm1524 Recruitment of MRE-11 to complex DNA damage is modulated by meiosis-specific chromosome organization.
C.elegans tm1298 Disabling the Fanconi Anemia Pathway in Stem Cells Leads to Radioresistance and Genomic Instability.
Human and Animal Cells HeLa(RCB0007) A Cell System-Assisted Strategy for Evaluating the Natural Antioxidant-Induced Double-Stranded DNA Break (DSB) Style.
Yeast Dual roles of yeast Rad51 N-terminal domain in repairing DNA double-strand breaks.
Yeast Maintenance of meiotic crossover against reduced double-strand break formation in fission yeast lacking histone H2A.Z.
Human and Animal Cells HeLa/Fucci(RCB2812) The Ubiquitin Ligase RNF138 Cooperates with CtIP to Stimulate Resection of Complex DNA Double-Strand Breaks in Human G1-Phase Cells.
Mice RBRC10583 BRCA2-DSS1 interaction is dispensable for RAD51 recruitment at replication-induced and meiotic DNA double strand breaks
Mice RBRC00886 Temperature sensitivity of DNA double-strand break repair underpins heat-induced meiotic failure in mouse spermatogenesis.
Human and Animal Cells HCT116(RCB2979) , CHO-K1(RCB0285) , HCT116-XRCC4(-/-)(RCB2981) , NIH3T3 Feline XRCC4 undergoes rapid Ku-dependent recruitment to DNA damage sites.
Human and Animal Cells HeLa.S3 Canonical non-homologous end joining in mitosis induces genome instability and is suppressed by M-phase-specific phosphorylation of XRCC4.
Human and Animal Cells V79(RCB0008) DNA-double strand breaks enhance the expression of major histocompatibility complex class II through the ATM-NF-κΒ-IRF1-CIITA pathway.
Human and Animal Cells HFL-III(RCB0523) The complexity of DNA double strand break is a crucial factor for activating ATR signaling pathway for G2/M checkpoint regulation regardless of ATM function.
C.elegans Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1-BARD1 in Caenorhabditis elegans.
Human and Animal Cells A549 Nontoxic concentration of DNA-PK inhibitor NU7441 radio-sensitizes lung tumor cells with little effect on double strand break repair.