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Species Resource Title
Human and Animal Cells COS-1(RCB0143) p300 collaborates with Sp1 and Sp3 in p21(waf1/cip1) promoter activation induced by histone deacetylase inhibitor.
Human and Animal Cells BeWo(RCB1644) Histone deacetylase inhibitors induce growth inhibition, cell cycle arrest and apoptosis in human choriocarcinoma cells.
Human and Animal Cells KP4(RCB1005) MAT2A Inhibition Blocks the Growth of MTAP-Deleted Cancer Cells by Reducing PRMT5-Dependent mRNA Splicing and Inducing DNA Damage.
General Microbes JCM 5827 , JCM 1658 , JCM 1238 , JCM 1672 , JCM 1673 (+)-Sesamin, a sesame lignan, is a potent inhibitor of gut bacterial tryptophan indole-lyase that is a key enzyme in chronic kidney disease pathogenesis.
Human and Animal Cells PC-12(RCB0009) Thapsigargin-induced apoptosis was prevented by glycogen synthase kinase-3 inhibitors in PC12 cells.
Human and Animal Cells HL60(RCB0041) Apicidin, a histone deacetylase inhibitor, induces differentiation of HL-60 cells.
Human and Animal Cells THP-1(RCB1189) Inhibition of tumor cell invasion and matrix degradation by aminopeptidase inhibitors.
Human and Animal Cells MH7A(RCB1512) Enhancement of anti-inflammatory tendency by SB203580, p38alpha specific inhibitor, in human fibroblast-like synoviocyte cell line, MH7A.
Human and Animal Cells K562 Aldo-keto reductase inhibitors increase the anticancer effects of tyrosine kinase inhibitors in chronic myelogenous leukemia.
Human and Animal Cells CAC0-2(RCB0988) , Hep G2(RCB0459) Structure-activity relationships of N-(3,5-dimethoxy-4-n-octyloxycinnamoyl)-N'-(3,4-dimethylphenyl)piperazine and analogues as inhibitors of acyl-CoA: cholesterol O-acyltransferase.
Prokaryotes B. subtilis Armeniaspirols inhibit the AAA+ proteases ClpXP and ClpYQ leading to cell division arrest in Gram-positive bacteria.
Human and Animal Cells MCF7(RCB1904) Identification of U83836E as a γ-glutamylcyclotransferase inhibitor that suppresses MCF7 breast cancer xenograft growth.
Human and Animal Cells HCE-T(RCB2280) Identification of sulfonic acids as efficient ecto-5'-nucleotidase inhibitors.
Human and Animal Cells K562(RCB0027) Effect of a novel antibiotic, heliquinomycin, on DNA helicase and cell growth.
Human and Animal Cells KUSA-H1(RCB1990) , 9-15C(RCB2323) , UV♀2(RCB1994) , StromaNKtert(RCB2350) The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
DNA material pHLUX20 (RDB18951) A bioluminescence assay using Nitrosomonas europaea for rapid and sensitive detection of nitrification inhibitors.
Human and Animal Cells MIA Paca2(RCB2094) Ribonucleotide reductase is an effective target to overcome gemcitabine resistance in gemcitabine-resistant pancreatic cancer cells with dual resistant factors.
Human and Animal Cells B16 , SK-MEL-28(RCB1930) WP1066, a small molecule inhibitor of the JAK/STAT3 pathway, inhibits ceramide glucosyltransferase activity.
Human and Animal Cells HF19(RCB0210) Synthesis, docking, cytotoxicity, and LTA4H inhibitory activity of new gingerol derivatives as potential colorectal cancer therapy.
Human and Animal Cells TGBC11TKB(RCB1148) Human SHMT inhibitors reveal defective glycine import as a targetable metabolic vulnerability of diffuse large B-cell lymphoma.