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  • Search Condition : Filter (MeSH = Extracellular Signal-Regulated MAP Kinases / metabolism)
Species Resource
DNA material pIL-2R gamma 2 (RDB01201) Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera.
C.intestinalis / (O.japonicus) Wild C. int Functional diversity of signaling pathways through G protein-coupled receptor heterodimerization with a species-specific orphan receptor subtype.
DNA material Human MDR1 cDNA (RDB01372) YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway.
DNA material MSM Mouse BAC (RDB04214) MSMg01-392H15 Novel regulatory mechanism and functional implication of plasminogen activator inhibitor-1 (PAI-1) expression in CpG-ODN-stimulated macrophages.
DNA material Human MDR1 cDNA (RDB01372) Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.
Cord blood stem cells for research UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.
Silkworms Identification of a new Sprouty protein responsible for the inhibition of the Bombyx mori nucleopolyhedrovirus reproduction.
DNA material pSCRG1-FLAG (RDB12800) Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells.
Drosophila A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility for Epithelial Invagination.
C.elegans tm3775 Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.
Mice B6.Cg-Tg(Drd2-YFP)364-5(RBRC02332) , C57BL/6J-Tg(mDrd1-YFP)680-1Koba (RBRC03111) , B6;129S-Rap1a<tm1Morz> Rap1b<tm1Morz>(RBRC04720) Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Mice B6;129-Ace3<tm1Osb>(RBRC04138) Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.
Yeast S. pombe strains Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells.
Mice B6.129S-Drd2<tm1Mok>(RBRC01081) Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.
DNA material p3AP1 (PMA) RE-TK hRluc(F) (RDB03452) p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor.
DNA material CS-CDF-CG-PRE (RDB04379) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis.
DNA material pCAG-Flag-Etv1 (RDB13214) , pCAG-Flag-Etv1act (RDB13215). Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells.
Drosophila Proteomic and functional genomic landscape of receptor tyrosine kinase and ras to extracellular signal-regulated kinase signaling.