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  • Search Condition : Filter (MeSH = Extracellular Signal-Regulated MAP Kinases / metabolism)
Species Resource
DNA material pIL-2R gamma 2 (RDB01201) Selective expansion of genetically modified T cells using an antibody/interleukin-2 receptor chimera.
C.intestinalis / (O.japonicus) Wild C. int Functional diversity of signaling pathways through G protein-coupled receptor heterodimerization with a species-specific orphan receptor subtype.
DNA material Human MDR1 cDNA (RDB01372) YC-1, a novel potential anticancer agent, inhibit multidrug-resistant protein via cGMP-dependent pathway.
DNA material MSM Mouse BAC (RDB04214) MSMg01-392H15 Novel regulatory mechanism and functional implication of plasminogen activator inhibitor-1 (PAI-1) expression in CpG-ODN-stimulated macrophages.
DNA material Human MDR1 cDNA (RDB01372) Cabozantinib reverses multidrug resistance of human hepatoma HepG2/adr cells by modulating the function of P-glycoprotein.
Cord blood stem cells for research UBASH3B/Sts-1-CBL axis regulates myeloid proliferation in human preleukemia induced by AML1-ETO.
Silkworms Identification of a new Sprouty protein responsible for the inhibition of the Bombyx mori nucleopolyhedrovirus reproduction.
C.elegans The AFF-1 exoplasmic fusogen is required for endocytic scission and seamless tube elongation.
DNA material pSCRG1-FLAG (RDB12800) Novel SCRG1/BST1 axis regulates self-renewal, migration, and osteogenic differentiation potential in mesenchymal stem cells.
Drosophila A Switch-like Activation Relay of EGFR-ERK Signaling Regulates a Wave of Cellular Contractility for Epithelial Invagination.
C.elegans tm3775 Expression pattern and first functional characterization of riok-1 in Caenorhabditis elegans.
DNA material pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393). ERK7 regulates ciliogenesis by phosphorylating the actin regulator CapZIP in cooperation with Dishevelled.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.
Mice B6.Cg-Tg(Drd2-YFP)364-5(RBRC02332) , C57BL/6J-Tg(mDrd1-YFP)680-1Koba (RBRC03111) , B6;129S-Rap1a<tm1Morz> Rap1b<tm1Morz>(RBRC04720) Phosphoproteomics of the Dopamine Pathway Enables Discovery of Rap1 Activation as a Reward Signal In Vivo.
Mice B6;129-Ace3<tm1Osb>(RBRC04138) Angiotensin-Converting Enzyme 3 (ACE3) Protects Against Pressure Overload-Induced Cardiac Hypertrophy.
Yeast S. pombe strains Identification of ACA-28, a 1'-acetoxychavicol acetate analogue compound, as a novel modulator of ERK MAPK signaling, which preferentially kills human melanoma cells.
Mice B6.129S-Drd2<tm1Mok>(RBRC01081) Endocytosis following dopamine D2 receptor activation is critical for neuronal activity and dendritic spine formation via Rabex-5/PDGFRβ signaling in striatopallidal medium spiny neurons.
DNA material p3AP1 (PMA) RE-TK hRluc(F) (RDB03452) p63/p51-induced onset of keratinocyte differentiation via the c-Jun N-terminal kinase pathway is counteracted by keratinocyte growth factor.
DNA material CS-CDF-CG-PRE (RDB04379) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) Pten deficiency in melanocytes results in resistance to hair graying and susceptibility to carcinogen-induced melanomagenesis.
DNA material pCAG-Flag-Etv1 (RDB13214) , pCAG-Flag-Etv1act (RDB13215). Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells.