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Species Resource Title
Human and Animal Cells CHO-K1(RCB0285) T75M-KCNJ2 mutation causing Andersen-Tawil syndrome enhances inward rectification by changing Mg2+ sensitivity.
Zebrafish HGj4A Rare Variants in BNC2 Are Implicated in Autosomal-Dominant Congenital Lower Urinary-Tract Obstruction.
C.elegans tm819 De novo mutations in KIF1A-associated neuronal disorder (KAND) dominant-negatively inhibit motor activity and axonal transport of synaptic vesicle precursors.
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Drosophila DGRC#118733 , DGRC#118734 Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
Human and Animal Cells RAW 264(RCB0535) , COS-7(RCB0539) A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
Human and Animal Cells RAW 264(RCB0535) Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand.
Human and Animal Cells ATDC5(RCB0565) , MC3T3-E1(RCB1126) , 10T1/2(RCB0247) , C2C12(RCB0987) New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.
Human and Animal Cells RAW 264(RCB0535) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
Drosophila CAS-0004 The Classic Lobe Eye Phenotype of Drosophila Is Caused by Transposon Insertion-Induced Misexpression of a Zinc-Finger Transcription Factor.
Arabidopsis / Cultured plant cells, genes pst17092 JAZ2 controls stomata dynamics during bacterial invasion.
Drosophila 4889R-4 , 3758R-1 , 3758R-5 Snail modulates JNK-mediated cell death in Drosophila.
DNA material , Human and Animal Cells human TICAM-2 expression vector (RDB16924) , human TICAM-2 C Flag expression vector (RDB16926) , human TICAM-2 C HA expression vector (RDB16928) , 293(RCB1637) TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.
Arabidopsis / Cultured plant cells, genes pst05666 MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-Mediated Rab7 Activation Regulates Tapetal Programmed Cell Death and Pollen Development.
C.elegans tm1595 , tm2241 , tm1320 , tm847 , tm1963 , tm1910 Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.
Human and Animal Cells MKN7(RCB0999) A dominant-negative N-terminal fragment of HER2 frequently expressed in breast cancers.
Human and Animal Cells Terminally differentiated neutrophils predominantly express Survivin-2 alpha, a dominant-negative isoform of survivin.
Human and Animal Cells 293(RCB1637) C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) , MRC-5(RCB0211) Two regions of the tail are necessary for the isoform-specific functions of nonmuscle myosin IIB.
Human and Animal Cells Cell type-specific regulation of RhoA activity during cytokinesis.