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Species Resource Title
Human and Animal Cells L929 Rac is activated by tumor necrosis factor alpha and is involved in activation of Erk.
Drosophila DGRC#118733 , DGRC#118734 Phosphorylation of 4E-BP by LRRK2 affects the maintenance of dopaminergic neurons in Drosophila.
Human and Animal Cells RAW 264(RCB0535) , COS-7(RCB0539) A novel mitogen-activated protein kinase phosphatase is an important negative regulator of lipopolysaccharide-mediated c-Jun N-terminal kinase activation in mouse macrophage cell lines.
Human and Animal Cells RAW 264(RCB0535) Possible involvement of IkappaB kinase 2 and MKK7 in osteoclastogenesis induced by receptor activator of nuclear factor kappaB ligand.
Human and Animal Cells ATDC5(RCB0565) , MC3T3-E1(RCB1126) , 10T1/2(RCB0247) , C2C12(RCB0987) New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells. Checkpoint of modulation by cyclic AMP.
Human and Animal Cells RAW 264(RCB0535) Involvement of p38 mitogen-activated protein kinase signaling pathway in osteoclastogenesis mediated by receptor activator of NF-kappa B ligand (RANKL).
Drosophila CAS-0004 The Classic Lobe Eye Phenotype of Drosophila Is Caused by Transposon Insertion-Induced Misexpression of a Zinc-Finger Transcription Factor.
Arabidopsis / Cultured plant cells, genes pst17092 JAZ2 controls stomata dynamics during bacterial invasion.
Drosophila 4889R-4 , 3758R-1 , 3758R-5 Snail modulates JNK-mediated cell death in Drosophila.
DNA material , Human and Animal Cells human TICAM-2 expression vector (RDB16924) , human TICAM-2 C Flag expression vector (RDB16926) , human TICAM-2 C HA expression vector (RDB16928) , 293(RCB1637) TIR-containing adapter molecule (TICAM)-2, a bridging adapter recruiting to toll-like receptor 4 TICAM-1 that induces interferon-beta.
Arabidopsis / Cultured plant cells, genes pst05666 MONENSIN SENSITIVITY1 (MON1)/CALCIUM CAFFEINE ZINC SENSITIVITY1 (CCZ1)-Mediated Rab7 Activation Regulates Tapetal Programmed Cell Death and Pollen Development.
C.elegans tm1595 , tm2241 , tm1320 , tm847 , tm1963 , tm1910 Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants.
Human and Animal Cells MKN7(RCB0999) A dominant-negative N-terminal fragment of HER2 frequently expressed in breast cancers.
Human and Animal Cells Terminally differentiated neutrophils predominantly express Survivin-2 alpha, a dominant-negative isoform of survivin.
Human and Animal Cells C-terminal LRRs of human Toll-like receptor 3 control receptor dimerization and signal transmission.
Human and Animal Cells MRC-5 SV1 TG1(RCB0207) , MRC-5(RCB0211) Two regions of the tail are necessary for the isoform-specific functions of nonmuscle myosin IIB.
Human and Animal Cells Cell type-specific regulation of RhoA activity during cytokinesis.
Human and Animal Cells MC3T3-E1(RCB1126) , C2C12(RCB0987) Continuous inhibition of MAPK signaling promotes the early osteoblastic differentiation and mineralization of the extracellular matrix.
Human and Animal Cells Functional cooperation among Ras, STAT5, and phosphatidylinositol 3-kinase is required for full oncogenic activities of BCR/ABL in K562 cells.
Human and Animal Cells MC3T3-E1(RCB1126) Macrophage migration inhibitory factor up-regulates matrix metalloproteinase-9 and -13 in rat osteoblasts. Relevance to intracellular signaling pathways.