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  • 検索条件 : 絞込み (MeSH = Histone Demethylases / genetics)
生物種 リソース名 タイトル
実験動物マウス RBRC05199 Maternal epigenetic factors in embryonic and postnatal development.
線虫 tmC27 Ectopic transcription due to inherited histone methylation may interfere with the ongoing function of differentiated neurons.
ヒト・動物細胞 , 遺伝子材料 C2C12(RCB0987) , pENTR4-H1 (RDB04395) , CS-RfA-EVBsd (RDB06090) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (REB04394) LSD1 defines the fiber type-selective responsiveness to environmental stress in skeletal muscle.
実験動物マウス RBRC05065 UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.
ヒト・動物細胞 Lu-165(RCB1184) SMARCA4 deficient tumours are vulnerable to KDM6A/UTX and KDM6B/JMJD3 blockade.
遺伝子材料 , ヒト・動物細胞 pENTR4-H1tetOx1 (RDB07916) , HL-60(RCB3683) LSD1 defines erythroleukemia metabolism by controlling the lineage-specific transcription factors GATA1 and C/EBPα.
ショウジョウバエ DGRC#104754 A KDM5-Prospero transcriptional axis functions during early neurodevelopment to regulate mushroom body formation.
実験動物マウス RBRC01834 UTX maintains the functional integrity of the murine hematopoietic system by globally regulating aging-associated genes.
ヒト・動物細胞 ATDC5(RCB0565) , 10T1/2(RCB0247) Arid5b facilitates chondrogenesis by recruiting the histone demethylase Phf2 to Sox9-regulated genes.
遺伝子材料 , ヒト・動物細胞 CS-RfA-EVBsd (RDB06090) , pENTR4-H1 (RDB04395) , pCAG-HIVgp (RDB04394) , pCMV-VSV-G-RSV-Rev (RDB04393) , ATN-1(RCB1440) Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas.
線虫 tm1231 Members of the H3K4 trimethylation complex regulate lifespan in a germline-dependent manner in C. elegans.
線虫 tm2469 HTZ-1/H2A.z and MYS-1/MYST HAT act redundantly to maintain cell fates in somatic gonadal cells through repression of ceh-22 in C. elegans.
線虫 tm3118 The H3K27 demethylase UTX-1 regulates C. elegans lifespan in a germline-independent, insulin-dependent manner.
線虫 tm3118 Histone demethylase UTX-1 regulates C. elegans life span by targeting the insulin/IGF-1 signaling pathway.
線虫 tm1231 Transgenerational epigenetic inheritance of longevity in Caenorhabditis elegans.
線虫 tm1905 Transdifferentiation. Sequential histone-modifying activities determine the robustness of transdifferentiation.
ヒト・動物細胞 A549 , RERF-LC-AI(RCB0444) The histone demethylase PHF8 is an oncogenic protein in human non-small cell lung cancer.
ヒト・動物細胞 293(RCB1637) Regulation of tissue factor pathway inhibitor-2 (TFPI-2) expression by lysine-specific demethylase 1 and 2 (LSD1 and LSD2).
実験動物マウス RBRC01828 New BRAF knockin mice provide a pathogenetic mechanism of developmental defects and a therapeutic approach in cardio-facio-cutaneous syndrome.
線虫 tm3136 and tm3118 The C. elegans H3K27 demethylase UTX-1 is essential for normal development, independent of its enzymatic activity.