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  • Search Condition : Filter (MeSH = Melanosomes / metabolism)
Species Resource Title
DNA material pEF-Rab10 (RDB20711) , pEF-Rab10(delta K) (RDB20712) Rab10 function in tubular endosome formation requires the N-terminal K3 residue and is disrupted by N-terminal tagging.
Human and Animal Cells B16F10(RCB2630) The CNC-family transcription factor Nrf3 coordinates the melanogenesis cascade through macropinocytosis and autophagy regulation.
DNA material , Human and Animal Cells CSII-CMV-MCS-IRES2-Bsd(RDB04385) , MMAc(RCB0808) , SK-MEL-28(RCB1930) , 293T(RCB2202) Biogenesis of fibrils requires C-mannosylation of PMEL.
Human and Animal Cells B16 mouse melanoma Disruption of melanosome transport in melanocytes treated with theophylline causes their degradation by autophagy.
DNA material pMRX-bsr-Myc-M-INK (RDB17955) , pMRX-bsr-mCherry-M-INK (RDB17956) , pEGFP-C1-Rab44 (RDB17957) , pEGFP-C1-Rab45 (RDB17958) Rab7B/42 Is Functionally Involved in Protein Degradation on Melanosomes in Keratinocytes.
DNA material pEF-T7-HPS4 (RDB17366) , pEF-T7-GST-RBD32/38 (RDB17371) RUTBC1 Functions as a GTPase-activating Protein for Rab32/38 and Regulates Melanogenic Enzyme Trafficking in Melanocytes.
Human and Animal Cells B16 melanoma 4A5(RCB0557) 3-O-Glyceryl-2-O-hexyl ascorbate suppresses melanogenesis by interfering with intracellular melanosome transport and suppressing tyrosinase protein synthesis.
DNA material pEF-mouse T7-Munc13-4 (RDB15181) Functional characterization of two RAB27A missense mutations found in Griscelli syndrome type 2.
DNA material pEGFP-C1-human TBC1D1 (RDB14982) , pEGFP-C1-human TBC1D2A (RDB14983) , pEGFP-C1-human TBC1D３ (RDB14985) , pEGFP-C1-human TBC1D4 (RDB14986) , pEGFP-C1-human TBC1D5 (RDB14987) , pEGFP-C1-human TBC1D6 (RDB14988) , pEGFP-C1-human TBC1D8A (RDB14990) , pEGFP-C1-human TBC1D8B (RDB14991) , pEGFP-C1-human TBC1D9A (RDB14992) , pEGFP-C1-human TBC1D9B (RDB14993) , ... Identification of EPI64 as a GTPase-activating protein specific for Rab27A.
DNA material pEF-FLAG-Varp (RDB14333) , pEF-T7-Varp (RDB14334) , pEF-HA-RACK1 (RDB14335) , pEF-T7-RACK1 (RDB14336) , pmStr-C1-RACK1 (RDB14337). A Varp-Binding Protein, RACK1, Regulates Dendrite Outgrowth through Stabilization of Varp Protein in Mouse Melanocytes.
Human and Animal Cells B16 melanoma 4A5(RCB0557) , HMV-II(RCB0777) Ectopic expression of syntaxin3 affects behaviors of B16 melanoma by controlling actin dynamics.
Human and Animal Cells B16 melanoma 4A5(RCB0557) Skin-lightening effect of a polyphenol extract from Acerola (Malpighia emarginata DC.) fruit on UV-induced pigmentation.
Human and Animal Cells GM95(RCB1026) , MEB4(RCB1027) Glycolipid-dependent sorting of melanosomal from lysosomal membrane proteins by lumenal determinants.
Human and Animal Cells HMV-II(RCB0777) Melanophilin directly links Rab27a and myosin Va through its distinct coiled-coil regions.
DNA material Slac2-a (RDB03422) , pEF-FLAG-mouse myosin Va (Brain type) (RDB15283) , pEF-FLAG-mouse Rab34 (RDB15394) , pEF-T7-GST (RDB19882) Slac2-a/melanophilin, the missing link between Rab27 and myosin Va: implications of a tripartite protein complex for melanosome transport.
Human and Animal Cells GM95(RCB1026) , MEB4(RCB1027) Hyperacidification of trans-Golgi network and endo/lysosomes in melanocytes by glucosylceramide-dependent V-ATPase activity.
C.elegans tm920 , tm1320 , tm584 , tm847 , tm935 , tm933 , tm920 , tm246 Genetic analysis of lysosomal trafficking in Caenorhabditis elegans.