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Species Resource Title
Mice RBRC05143 The volume-regulated anion channel LRRC8C suppresses T cell function by regulating cyclic dinucleotide transport and STING-p53 signaling.
Mice RBRC00806 TMBIM6 (transmembrane BAX inhibitor motif containing 6) enhances autophagy through regulation of lysosomal calcium.
Mice RBRC09485 The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake.
DNA material , Human and Animal Cells mTmc1ex1 pcDNA3.1(+) (RDB20272) , 293T(RCB2202) A Mechanosensitive Channel, Mouse Transmembrane Channel-Like Protein 1 (Mtmc1) Is Translated from a Splice Variant mTmc1ex1 but Not from the Other Variant mTmc1ex2.
DNA material pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) The novel ZEB1-upregulated protein PRTG induced by Helicobacter pylori infection promotes gastric carcinogenesis through the cGMP/PKG signaling pathway.
DNA material CSII-CMV-MCS-IRES2-Venus (RDB04383) , pCMV-VSV-G-RSV-Rev (RDB04393) , pCAG-HIVgp (RDB04394) Insulin-induced genes INSIG1 and INSIG2 mediate oxysterol-dependent activation of the PERK-eIF2α-ATF4 axis.
Mice RBRC00858 The cGas-Sting Signaling Pathway Is Required for the Innate Immune Response Against Ectromelia Virus.
DNA material pcDNA3-HA-hArfaptin1 (RDB20097) , pcDNA3-HA-hArfaptin2 (RDB20098) , EGFP-hArfaptin1 (RDB20099) , EGFP-hArfaptin2 (RDB20100) , hARL1(WT)-EGFP (RDB20101) , hARL1(Q71L)-EGFP (RDB20102) , hARL1(T31N)-EGFP (RDB20103) Arfaptins are localized to the trans-Golgi by interaction with Arl1, but not Arfs.
Yeast BY23849 (BY4741) The very-long-chain fatty acid elongase Elo2 rescues lethal defects associated with loss of the nuclear barrier function in fission yeast cells.
Human and Animal Cells PANC-1(RCB2095) Stomatin‑like protein 2 induces metastasis by regulating the expression of a rate‑limiting enzyme of the hexosamine biosynthetic pathway in pancreatic cancer.
C.elegans tm390 , tm14710 , tm3568 , FX30203 INPP5K and Atlastin-1 maintain the nonuniform distribution of ER-plasma membrane contacts in neurons.
C.elegans tm10626 PDZD-8 and TEX-2 regulate endosomal PI(4,5)P2 homeostasis via lipid transport to promote embryogenesis in C. elegans.
DNA material pMRXIP-GFP-hATG2A (RDB19782) Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets.
DNA material pMXs-IP-HA-Parkin (RDB19764) , pMXs-IP-GFP-Omp25 (RDB19786) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
DNA material p3xFLAG-CMV10-mApg16L (RDB20243) Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate.
Yeast BYP9642 A nuclear membrane-derived structure associated with Atg8 is involved in the sequestration of selective cargo, the Cvt complex, during autophagosome formation in yeast.
Human and Animal Cells CHO-K1(RCB0285) Hepatocyte growth factor activator inhibitor type 1 is a specific cell surface binding protein of hepatocyte growth factor activator (HGFA) and regulates HGFA activity in the pericellular microenvironment.
Yeast pAL-KS , pAU-KS The fission yeast gmn2+ gene encodes an ERD1 homologue of Saccharomyces cerevisiae required for protein glycosylation and retention of luminal endoplasmic reticulum proteins.
DNA material pMXs-puro-RFP-ATG9A (RDB19627) , pMRX-IP-SECFP-hATG16L1 (RDB19635) Temporal analysis of recruitment of mammalian ATG proteins to the autophagosome formation site.
DNA material pEGFP-C1-hATG2A (RDB19631) Mammalian Atg2 proteins are essential for autophagosome formation and important for regulation of size and distribution of lipid droplets.