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  • Search Condition : Filter (MeSH = Mitogen-Activated Protein Kinase 1 / metabolism)
Species Resource
DNA material APP cDNA (AZ-10) Amyloid beta protein precursor is involved in the growth of human colon carcinoma cell in vitro and in vivo.
Mice M100174 Phenotypic characterization of a new Grin1 mutant mouse generated by ENU mutagenesis.
DNA material pZRmERK2 (RDB01796) alpha-Synuclein forms a complex with transcription factor Elk-1.
Rats SHRSP/Izm(strainID=409) , WKY/Izm(strainID=412) Caffeic acid inhibits vascular smooth muscle cell proliferation induced by angiotensin II in stroke-prone spontaneously hypertensive rats.
Cellular slime molds G24686 MAP kinases have different functions in Dictyostelium G protein-mediated signaling.
C.elegans tm3886 , tm853 DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance.
C.elegans tm1746 MAPK signaling couples SCF-mediated degradation of translational regulators to oocyte meiotic progression.
C.elegans tm1944 DAF-18/PTEN signals through AAK-1/AMPK to inhibit MPK-1/MAPK in feedback control of germline stem cell proliferation.
Silkworms Cell proliferation by silk gut incorporating FGF-2 protein microcrystals.
DNA material pGEX-GFP-ERK2-His (RDB14152) , pCMV-GFP-ERK2 (RDB14156) , pACYC184-Venus-MEK1 (S218/222E , delta32-51) (RDB14154). Conversion of graded phosphorylation into switch-like nuclear translocation via autoregulatory mechanisms in ERK signalling.
C.elegans tm1580 , tm659 , tm544 , tm574 , tm1743 Multiple ERK substrates execute single biological processes in Caenorhabditis elegans germ-line development.
Cellular slime molds S00342 RasC is required for optimal activation of adenylyl cyclase and Akt/PKB during aggregation.
Human and Animal Cells NB1RGB(RCB0222) The plant alkaloid conophylline inhibits matrix formation of fibroblasts.
Human and Animal Cells PC-12(RCB0009) Cholinesterase inhibitor rivastigmine enhances nerve growth factor-induced neurite outgrowth in PC12 cells via sigma-1 and sigma-2 receptors.
Human and Animal Cells E14tg2a(AES0135) Activin A in combination with ERK1/2 MAPK pathway inhibition sustains propagation of mouse embryonic stem cells.
Human and Animal Cells RGM1(RCB0876) Gastrin stimulates MMP-1 expression in gastric epithelial cells: putative role in gastric epithelial cell migration.
Human and Animal Cells 293(RCB1637) Sensitization of H2O2-induced TRPM2 activation and subsequent interleukin-8 (CXCL8) production by intracellular Fe(2+) in human monocytic U937 cells.
Human and Animal Cells Membrane sialidase NEU3 is highly expressed in human melanoma cells promoting cell growth with minimal changes in the composition of gangliosides.
Human and Animal Cells Zfat-deficiency results in a loss of CD3ζ phosphorylation with dysregulation of ERK and Egr activities leading to impaired positive selection.
Human and Animal Cells Inhibition of nerve growth factor-induced neurite outgrowth from PC12 cells by dexamethasone: signaling pathways through the glucocorticoid receptor and phosphorylated Akt and ERK1/2.