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  • Search Condition : Filter (MeSH = Protein Phosphatase 2 / genetics)
Species Resource Title
Human and Animal Cells SH-10-TC(RCB1940) Selective Inhibition of STRN3-Containing PP2A Phosphatase Restores Hippo Tumor-Suppressor Activity in Gastric Cancer.
Analysis of the potential role of fission yeast PP2A in spindle assembly checkpoint inactivation.
Human and Animal Cells K562 TOPK is regulated by PP2A and BCR/ABL in leukemia and enhances cell proliferation.
Algae NIES-4344 , NIES-4345 First Report of Microcystis Strains Producing MC-FR and -WR Toxins in Japan.
Drosophila Protein phosphatase PP2A regulates microtubule orientation and dendrite pruning in Drosophila.
Yeast FY9908 , FY9910 , FY21019 Maf1-dependent transcriptional regulation of tRNAs prevents genomic instability and is associated with extended lifespan.
Yeast The fission yeast Greatwall-Endosulfine pathway is required for proper quiescence/G0 phase entry and maintenance.
C.elegans tm655 Protein phosphatase 2A cooperates with the autophagy-related kinase UNC-51 to regulate axon guidance in Caenorhabditis elegans.
C.elegans tm395 , tm655 Protein phosphatase 2A-SUR-6/B55 regulates centriole duplication in C. elegans by controlling the levels of centriole assembly factors.
Human and Animal Cells RAW 264(RCB0535) Protein phosphatase 2A Cα is involved in osteoclastogenesis by regulating RANKL and OPG expression in osteoblasts.
Human and Animal Cells Regulated interaction of protein phosphatase 1 and protein phosphatase 2A with phospholipase C-related but catalytically inactive protein.
Yeast ZDS1 , IGO2 plasmids Comparative genetic analysis of PP2A-Cdc55 regulators in budding yeast.
DNA material pLL3.7 K122 FH-TAZ-ires-GFP-TEAD-responsive-H2B mCherry (RDB13967) , pFLAG-human yes-associated protein (YAP)1 (RDB13968) , pClneoMyc-LATS1 (RDB13969) , pClneoMyc-LATS2 (RDB13970) , pClneoLuc-PP1A (RDB13971) , pClneoLuc-PP2A (RDB13972). A cell-based screening for TAZ activators identifies ethacridine, a widely used antiseptic and abortifacient, as a compound that promotes dephosphorylation of TAZ and inhibits adipogenesis in C3H10T1/2 cells.
Yeast NA The protein phosphatase Siw14 controls caffeine-induced nuclear localization and phosphorylation of Gln3 via the type 2A protein phosphatases Pph21 and Pph22 in Saccharomyces cerevisiae.
Yeast BYP1613(ZDS1) Nuclear PP2A-Cdc55 prevents APC-Cdc20 activation during the spindle assembly checkpoint.
Human and Animal Cells MC3T3-E1(RCB1126) Reduction of protein phosphatase 2A Cα enhances bone formation and osteoblast differentiation through the expression of bone-specific transcription factor Osterix.
Arabidopsis / Cultured plant cells, genes pda08867 Specificity of RCN1-mediated protein phosphatase 2A regulation in meristem organization and stress response in roots.