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論文 - 一覧

  • 103 Hits
  • 検索条件 : 絞込み (MeSH = Ubiquitin-Protein Ligases / metabolism*)
生物種 リソース名 タイトル
遺伝子材料 CSII-CMV-MCS-IRES2-Bsd (RDB04385) RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair.
ヒト・動物細胞 293T(RCB2202) E3 ligase Nedd4l promotes antiviral innate immunity by catalyzing K29-linked cysteine ubiquitination of TRAF3.
遺伝子材料 CS-RfA-ETBsd (RDB07917) UV-induced activation of ATR is mediated by UHRF2.
ヒト・動物細胞 HUDEP-2(RCB4557) The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells.
線虫 tm1046 , tm1515 O-GlcNAc transferase OGT-1 and the ubiquitin ligase EEL-1 modulate seizure susceptibility in C. elegans.
遺伝子材料 pMXs-IP-HA-Parkin (RDB19764) , pMXs-IP-GFP-Omp25 (RDB19786) Parkin mediates proteasome-dependent protein degradation and rupture of the outer mitochondrial membrane.
遺伝子材料 pClgn1.1-Trim41-PA-1D4 (RDB19656) Trim41 is required to regulate chromosome axis protein dynamics and meiosis in male mice.
ショウジョウバエ DGRC#125656 The tumor suppressor archipelago E3 ligase is required for spermatid differentiation in Drosophila testis.
ゼブラフィッシュ , ヒト・動物細胞 Tg(6xTcf/LefBS-miniP:d2EGFP) , Cle-H3(RCB0549) A phospho-switch controls RNF43-mediated degradation of Wnt receptors to suppress tumorigenesis.
ショウジョウバエ 11861R-2 The E3 ubiquitin ligase adaptor Tango10 links the core circadian clock to neuropeptide and behavioral rhythms.
ヒト・動物細胞 OP9(RCB1124) Ablation of Fbxw7 eliminates leukemia-initiating cells by preventing quiescence.
ヒト・動物細胞 C2C12(RCB0987) ZSWIM8 is a myogenic protein that partly prevents C2C12 differentiation.
ヒト・動物細胞 K562(RCB0027) Fbw7 promotes ubiquitin-dependent degradation of c-Myb: involvement of GSK3-mediated phosphorylation of Thr-572 in mouse c-Myb.
ヒト・動物細胞 HuH-7(RCB1366) Overexpression of WWP1 promotes tumorigenesis and predicts unfavorable prognosis in patients with hepatocellular carcinoma.
遺伝子材料 PINK1_WT-IRES-GFP-NLS (RDB18946) , PINK1_KD-IRES-GFP-NLS (RDB18947) , MUL1_WT-IRES-GFP-NLS (RDB18948) , MUL1_LD-IRES-GFP-NLS (RDB18949) Gemcitabine induces Parkin-independent mitophagy through mitochondrial-resident E3 ligase MUL1-mediated stabilization of PINK1.
ゼブラフィッシュ hspGFF15A  , Tg(UAS:GFP) Mib1 contributes to persistent directional cell migration by regulating the Ctnnd1-Rac1 pathway.
ショウジョウバエ pBFv-U6.2 Hakai is required for stabilization of core components of the m6A mRNA methylation machinery.
遺伝子材料 pCAGGS (RDB08938) Thalidomide and its metabolite 5-hydroxythalidomide induce teratogenicity via the cereblon neosubstrate PLZF.
線虫 tm1145 BRCA1-BARD1 Regulates Axon Regeneration in Concert with the Gqα-DAG Signaling Network.
線虫 Meiotic Double-Strand Break Processing and Crossover Patterning Are Regulated in a Sex-Specific Manner by BRCA1-BARD1 in Caenorhabditis elegans.