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  • Search Condition : Filter (MeSH = Vesicular Transport Proteins / metabolism)
Species Resource Title
Drosophila Retromer promotes the lysosomal turnover of mtDNA.
Human and Animal Cells 201B7(HPS0063) The impact of VPS35 D620N mutation on alternative autophagy and its reversal by estrogen in Parkinson's disease.
C.elegans tm1595 , tm5356 , tm847 , tm2423 , tm2404 , tm3643 , tm1320 SNX-3 mediates retromer-independent tubular endosomal recycling by opposing EEA-1-facilitated trafficking.
DNA material pEGFP-C1-hRUTBC3-R165A (RDB19704) , pEGFP-C1-hTBC1D18-R584K  (RDB19705) , pGEX-4T-3-APPL1-N (RDB19706) TBC1D18 is a Rab5-GAP that coordinates endosome maturation together with Mon1.
DNA material pMRXIP-GFP-hATG2A (RDB19782) Differential requirement for ATG2A domains for localization to autophagic membranes and lipid droplets.
Arabidopsis / Cultured plant cells, genes pst18264 A unique plant ESCRT component, FREE1, regulates multivesicular body protein sorting and plant growth.
DNA material pGEXM (VAT1, Full-length) (RDB19564) , pGEXM (VAT1, 37-393) (RDB19565) , pGEXM (VAT1, 43-393) (RDB19566) Structural insights into vesicle amine transport-1 (VAT-1) as a member of the NADPH-dependent quinone oxidoreductase family.
Drosophila Caspar, an adapter for VAPB and TER94, modulates the progression of ALS8 by regulating IMD/NFκB-mediated glial inflammation in a Drosophila model of human disease.
DNA material T7-NLS hCas9-pA (RDB13130) , pT7-3xFLAG-NLS-Flpe-polyA plasmid (RDB16011) EXOC1 plays an integral role in spermatogonia pseudopod elongation and spermatocyte stable syncytium formation in mice.
Yeast FY31941 Regulation of inorganic polyphosphate is required for proper vacuolar proteolysis in fission yeast.
Arabidopsis / Cultured plant cells, genes pda12787 TRIPP Is a Plant-Specific Component of the Arabidopsis TRAPPII Membrane Trafficking Complex with Important Roles in Plant Development.
Yeast FY23684, FY23692 Analysis of the SNARE Stx8 recycling reveals that the retromer-sorting motif has undergone evolutionary divergence.
Human and Animal Cells ST2(RCB0224) Rab27a and Rab27b are involved in stimulation-dependent RANKL release from secretory lysosomes in osteoblastic cells.
C.elegans tm6119 Broadly conserved roles of TMEM131 family proteins in intracellular collagen assembly and secretory cargo trafficking.
C.elegans tm3425 , tm2508 The RBG-1-RBG-2 complex modulates autophagy activity by regulating lysosomal biogenesis and function in C. elegans.
C.elegans tm4790 EIPR1 controls dense-core vesicle cargo retention and EARP complex localization in insulin-secreting cells.
C.elegans tm4536 The exocyst complex and Rab5 are required for abscission by localizing ESCRT III subunits to the cytokinetic bridge.
C.elegans tm920 , tm1892 , tm1125 , tm592 , tm2241 Function and regulation of the Caenorhabditis elegans Rab32 family member GLO-1 in lysosome-related organelle biogenesis.
C.elegans tm5267 In vivo induction of membrane damage by β-amyloid peptide oligomers.
Yeast FYP4600 Sec16 function in ER export and autophagy is independent of its phosphorylation in Saccharomyces cerevisiae.