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  • 181 Hits
  • Search Condition : Filter (MeSH = Apoptosis / genetics)
Species Resource Title
Human and Animal Cells Saos-2(RCB0428) Inhibition of mutant p53 phosphorylation at serine 15 or serine 315 partially restores the function of wild-type p53.
Human and Animal Cells Ba/F3(RCB0805) Murine leukemia retrovirus integration induces the formation of transcription factor complexes on palindromic sequences in the signal transducer and activator of transcription factor 5a gene during the development of pre-B lymphomagenesis.
Human and Animal Cells JHOC-7(RCB1688) , JHOC-9(RCB2226) MDM2 is a potential therapeutic target and prognostic factor for ovarian clear cell carcinomas with wild type TP53.
Human and Animal Cells ATDC5(RCB0565) FGF-2 inhibits TNF-α mediated apoptosis through upregulation of Bcl2-A1 and Bcl-xL in ATDC5 cells.
Human and Animal Cells MFH-ino(RCB0749) , H-EMC-SS(RCB0508) , NRS-1(RCB1188) Expression of minichromosome maintenance-2 in human malignant fibrous histiocytomas: Correlations with Ki-67 and P53 expression, and apoptosis.
Human and Animal Cells DU145(RCB2143) , PC-3(RCB2145) Basic helix-loop-helix transcription factor DEC2 functions as an anti-apoptotic factor during paclitaxel-induced apoptosis in human prostate cancer cells.
Human and Animal Cells KGN(RCB1154) MiR-222 promotes the progression of polycystic ovary syndrome by targeting p27 Kip1.
Zebrafish Tg(6xTcf/LefBS-miniP:d2EGFP) , Tg(6xTcf/LefBS-miniP:Eluc-CP) Cell competition corrects noisy Wnt morphogen gradients to achieve robust patterning in the zebrafish embryo.
Human and Animal Cells IEC 6(RCB0993) Autophagy deficiency exacerbates colitis through excessive oxidative stress and MAPK signaling pathway activation.
Human and Animal Cells RCC10RGB(RCB1151) A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis.
C.elegans tm5211 , tm2679 The stress-responsive gene GDPGP1/mcp-1 regulates neuronal glycogen metabolism and survival.
C.elegans tm3948 , tm3425 , tm1226 , tm10601 , tm6801 Autophagy of germ-granule components, PGL-1 and PGL-3, contributes to DNA damage-induced germ cell apoptosis in C. elegans.
Drosophila DGRC#101079 , DGRC#109551 A ribosomal protein S5 isoform is essential for oogenesis and interacts with distinct RNAs in Drosophila melanogaster.
Human and Animal Cells ST2(RCB0224) Osteoadherin serves roles in the regulation of apoptosis and growth in MC3T3‑E1 osteoblast cells.
Human and Animal Cells G-415(RCB2640) Overexpression of SNORA21 suppresses tumorgenesis of gallbladder cancer in vitro and in vivo.
Drosophila 7788R-1 , 7788R-2 , 5370R-2 Characterization of TNF-induced cell death in Drosophila reveals caspase- and JNK-dependent necrosis and its role in tumor suppression.
Mice B6.Cg-Trp53/Rbrc(RBRC01361) Translationally controlled tumor protein (TCTP) plays a pivotal role in cardiomyocyte survival through a Bnip3-dependent mechanism.
Drosophila DGRC#206863 Sec71 functions as a GEF for the small GTPase Arf1 to govern dendrite pruning of Drosophila sensory neurons.
Drosophila DGRC#111645 Developmentally regulated autophagy is required for eye formation in Drosophila.
DNA material , Human and Animal Cells p3XFLAG-CDCA7 WT (RDB17374) , p3XFLAG-CDCA7 R274C (RDB17375) , p3XFLAG-HELLS WT (RDB17376) , p3XFLAG-HELLS Q699R (RDB17377) , DNMT3B px330 (RDB17378) , ZBTB24 px330 (RDB17379) , CDCA7 px330 (RDB17380) , HELLS px330 (RDB17381) , Ku80 px330 (RDB17382) , HEV0190(HEV0190) CDCA7 and HELLS mutations undermine nonhomologous end joining in centromeric instability syndrome.